Hydroxyethyl starches in intensive care medicine: Status quo and perspectives;Hydroxyethylstärke in der intensivmedizin: Status quo und perspektiven

Anasthesiologie und Intensivmedizin

Volumn 51, Issue 4, 2010, Pages 211-218

  Van Aken, Hugo ^a   Roewer, N ^b   Noldge Schomburg G ^c   Goetz, A E ^d   Marx, G ^e   Zacharowski, K ^f  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^c ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^f GOETHE UNIVERSITY   (Germany)

Author keywords

Albumin; Gelatine; Hydroxyethyl starch; Intensive care medicine; Volume therapy

Indexed keywords

HETASTARCH; HUMAN ALBUMIN; INFUSION FLUID;

ACUTE KIDNEY FAILURE; APACHE; COLLOID; CONTROLLED STUDY; HEART FAILURE; HUMAN; HYPERVOLEMIA; HYPOVOLEMIA; INFUSION; INTENSIVE CARE; OXYGENATION; REVIEW; SEPSIS;

EID: 77951555703     PISSN: 01705334     EISSN: 14390256     Source Type: Journal    
DOI: None     Document Type: Review

References (49)

1. Payen D, De Pont AC, Sakr Y, Spies C, Reinhart K, et al. A positive fluid balance is associated with a worse outcome in patients with acute renal failure. Crit Care 2008;12:R74. (Pubitemid 351866029)
2. Klein MB, Hayden D, Elson C, Nathens AB, Gamelli RL, et al. The association between fluid administration and outcome following major burn: a multicenter study. Ann Surg 2007;245:622-628. (Pubitemid 46555667)
3. Sakr Y, Vincent JL, Reinhart K, Groeneveld J, Michalopoulos A, et al. High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest 2005;128:3098-3108 (Pubitemid 41698628)
4. Van Aken H, Jacob M, Westphal M, Zwissler B. Infusionstherapie in der Anästhesiologie und Intensivmedizin: Gestern, heute und morgen. Anästh Intensivmed 2009;50:338-345.
5. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R; SAFE Study Investigators. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004;350:2247-2256. (Pubitemid 38669207)
6. SAFE Study Investigators. Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med 2007;357:874-884. (Pubitemid 47347321)
7. Bellomo R, Morimatsu H, Presneill J, French C, Cole L, et al. SAFE Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Effects of saline or albumin resuscitation on standard coagulation tests. Crit Care Resusc 2009;11:250-256.
8. Moran M; Kapsner C. Acute renal failure associated with elevat ed plasma oncotic pressure. N Engl J Med 1987;317:150-153. (Pubitemid 17096463)
9. Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008;358:125-139.
10. Schortgen F, Lacherade JC, Bruneel F, Cattaneo I, Hemery F, et al. Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study. Lancet 2001;357:911-916. (Pubitemid 32247279)
11. Schortgen F, Girou E, Deye N, Brochard L; CRYCO Study Group. The risk associated with hyperoncotic colloids in patients with shock. Intensive Care Med 2008;34:2157-2168.
12. Hartog C, Reinhart K. Contra: Hydroxyethyl starch solutions are unsafe in critically ill patients. Intensive Care Med 2009;35:1337-1342.
13. Hartog C, Reinhart K. Modern starches are not safer than old ones. Anesth Analg 2009;109:1346.
14. Gallandat Huet RC, Siemons AW, Baus D, van Rooyen-Butijn WT, Haagenaars JA, et al. A novel hydroxyethyl starch (Voluven) for effective perioperative plasma volume substitution in cardiac surgery. Can J Anaesth 2000;47:1207-1215. (Pubitemid 32098997)
15. Jungheinrich C, Sauermann W, Bepperling F, Vogt NH. Volume efficacy and reduced influence on measures of coagulation using hydroxyethyl starch 130/0.4 (6%) with an optimised in vivo molecular weight in orthopaedic surgery : a randomised, double-blind study. Drugs R D 2004;5:1-9.
16. Gandhi SD, Weiskopf RB, Jungheinrich C, Koorn R, Miller D, et al. Volume replacement therapy during major orthopedic surgery using Voluven (hydroxyethyl starch 130/0.4) or hetastarch. Anesthesiology 2007;106:1120-1127.
17. Westphal M, James MF, Kozek-Langenecker S, Stocker R, Guidet B, et al. Hydroxyethyl starches. Different products - different effects. Anesthesiology 2009;111:187-202.
18. Waitzinger J, Bepperling F, Pabst G, Opitz J. Hydroxyethyl starch (HES) [130/0.4], a new HES specification: pharmacokinetics and safety after multiple infusions of 10% solution in healthy volunteers. Drugs R D 2003;4:149-157.
19. Leuschner J, Opitz J, Winkler A, Scharpf R, Bepperling F. Tissue Storage of (14)C-Labelled Hydroxyethyl Starch (HES) 130/0.4 and HES 200/0.5 after Repeated Intravenous Administration to Rats. Drugs R D 2003;4:331-338.
20. Langeron O, Doelberg M, Ang ET, Bonnet F, Capdevila X, Coriat P. Voluven, a lower substituted novel Hydroxyethyl Starch (HES 130/0.4), causes fewer effects on coagulation in major orthopedic surgery than HES 200/0.5. Anesth Analg 2001;92:855-862. (Pubitemid 32239122)
21. Kozek-Langenecker SA, Jungheinrich C, Sauermann W, van der Linden P. The effects of hydroxyethyl starch 130/0.4 (6%) on blood loss and use of blood products in major surgery: A pool ed analysis of randomized clinical trials. Anesth Analg 2008;107:382-390.
22. Kumle B, Boldt J, Piper S, Schmidt C, Suttner S, Salopek S. The influence of different intravascular volume replacement regimens on renal function in the elderly. Anesth Analg. 1999;89:1124-1130. (Pubitemid 29521926)
23. Boldt J, Ducke M, Kumle B, Papsdorf M, Zurmeyer EL. Influence of different volume replacement strategies on inflammation and endothelial activation in the elderly undergoing major abdominal surgery. Intensive Care Med 2004;30:416-422. (Pubitemid 38375615)
24. Boldt J, Schöllhorn T, Mayer J, Piper S, Suttner S. The value of an albumin-based intravascular volume replacement strategy in elderly patients undergoing major abdominal surgery. Anesth Analg 2006;103:191-199. (Pubitemid 44036058)
25. Jungheinrich C, Scharpf R, Wargenau M, Bepperling F, Baron JF. The pharmacokinetics and tolerability of an intravenous infusion of the new hydroxyethyl starch 130/0.4 (6%, 500ml) in mild-to-severe renal impairment. Anesth Analg 2002;95:544-551. (Pubitemid 35006837)
26. Standl T, Lochbuehler H, Galli C, Reich A, Dietrich G, Hagemann H. HES 130/0.4 (Voluven®) or human albumin in children younger than 2 yr undergoing non-cardiac surgery. A prospective, randomized, open label, multicentre trial. Eur J Anaesthesiol 2008;25:437-445. (Pubitemid 351629970)
27. Hanart C, Khalife M, De Villé A, Otte F, De Hert S, Van der Linden P. Perioperative volume replacement in children undergoing cardiac surgery: Albumin versus hydroxyethyl starch 130/0.4. Crit Care Med 2009;37:696-701.
28. Lang K, Boldt J, Suttner S, Haisch G. Colloids versus crys - talloids and tissue oxygen tension in patients undergoing major abdominal surgery. Anesth Analg 2001;93:405-409. (Pubitemid 32701540)
29. Michard F, Teboul JL. Predicting fluid responsiveness in ICU patients: a critical analysis of the evidence. Chest 2002;121:2000-2008. (Pubitemid 34634425)
30. Michard F, Boussat S, Chemla D, Anguel N, Mercat A, et al. Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Resp Crit Care Med 2000;162:134-138. (Pubitemid 30469810)
31. Reuter DA, Goetz AE, Peter K. Einschätzung der Volumen- reagibilität beim beatmeten Patienten. Anaesthesist 2003;52:1005-1007,1010- 1013. (Pubitemid 37433534)
32. Goepfert MS, Reuter DA, Akyol D, Lamm P, Kilger E, Goetz AE. Goal-directed fluid management reduces vasopressor and catecholamine use in cardiac surgery patients. Intensive Care Med 2007;33:96-103. (Pubitemid 46115475)
33. Jacob M, Chappell D, Rehm M. Clinical update: Perioperative fluid management. Lancet 2007;369:1984-1986. (Pubitemid 46899170)
34. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-1377.
35. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, et al. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008;36:296-327.
36. Chappell D, Jacob M, Hofmann-Kiefer K, Conzen P, Rehm M. A rational approach to perioperative fluid management. Anesthesiology 2008;109:723-740.
37. Lacherade JC, Outin H, De Jonghe B. Insulin and penta starch for severe sepsis. N Engl J Med 2008;358:2071-2072. (Pubitemid 351656472)
38. Bracco D, Schricker T, Carvalho G. Insulin and pentastarch for severe sepsis. N Engl J Med 2008;358:2072.
39. Muller L, Jaber S, Lefrant JY. Insulin and pentastarch for severe sepsis. N Engl J Med 2008;358:2072-2073.
40. Van den Berghe G, Wilmer A, Bouillon R. Insulin and pentastarch for severe sepsis. N Engl J Med 2008;358:2073.
41. Ellger B, van den Heuvel I, Poelaert J. Insulin and penta starch for severe sepsis. N Engl J Med 2008;358:2073-2074. (Pubitemid 351656476)
42. Sakr Y, Payen D, Reinhart K, Sipmann FS, Zavala E, et al. Effects of hydroxyethyl starch administration on renal function in critically ill patients. Br J Anaesth 2007;98:216-224. (Pubitemid 47072001)
43. Palumbo D, Servillo G, D'Amato L, Volpe ML, Capogrosso G, et al. The effects of hydroxyethyl starch solution in critically ill patients. Minerva Anestesiol 2006;72:655-664. (Pubitemid 44251571)
44. Neff TA, Doelberg M, Jungheinrich C, Sauerland A, Spahn DR, Stocker R. Repetitive large-dose infusion of the novel hydroxyethyl starch 130/0.4 in patients with severe head injury. Anesth Analg 2003;96:1453-1459. (Pubitemid 36512891)
45. Dart AB, Mutter TC, Ruth CA, Taback SP. Hydroxyethyl starch (HES) versus other fluid therapies: Effects on kidney function. Cochrane Database Syst Rev 2010;20(1):CD007594.
46. Wiedermann CJ. Systematic review of randomized clinical trials on the use of hydroxyethyl starch for fluid management in sepsis. BMC Emerg Med 2008;8:1.
47. Zarychanski R, Turgeon AF, Fergusson DA, Cook, DJ, Hébert P, Bagshaw, SM et al. Renal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: Systematic review and meta-analysis of randomized trials. Open Medicine 2009; 3:E196-E209. http://www.openmedicine.ca/ article/ view/291/276 - Accessed 09 Feb 20130.
48. Ertmer C, Koehler G, Rehberg S, Morelli A, Lange M, et al. Renal effects of saline-based 10% pentastarch versus 6% tetrastarch infusion in ovine endotoxemic shock. Anesthesiology 2010,in press.
49. Jungheinrich C, Neff TA. Pharmacokinetics of hydroxyethyl starch. Clin Pharmacokinet 2005;44:681-699.