Effect of multifold charge groups and imidazole-4-carboxaldehyde on physicochemical characteristics and transfection of cationic polyphosphazenes/DNA complexes

International Journal of Pharmaceutics

Volumn 390, Issue 2, 2010, Pages 191-197

  Yang, Yongxin ^a   Zhang, Zhiwen ^a   Chen, Lingli ^a   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Complexes; DNA; Gene delivery; Imidazole 4 carboxaldehyde; Poly(2 (2 aminoethyoxy)ethoxy)phosphazene

Indexed keywords

ALDEHYDE; AMINE; IMIDAZOLE 4 CARBOXALDEHYDE; PLASMID DNA; POLY[2 (2 AMINOETHYOXY)ETHOXY IMIDAZOLE 4 CARBOXALDEHYDE]PHOSPHAZENE; POLY[2 (2 AMINOETHYOXY)ETHOXY]PHOSPHAZENE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOCOMPATIBILITY; CELL VIABILITY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA DRUG COMPLEX; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG FORMULATION; DRUG SYNTHESIS; DRUG UPTAKE; GENE TRANSFER; GENETIC TRANSFECTION; PERIODIC ACID SCHIFF STAIN; PH MEASUREMENT; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURAL GENE;

ALDEHYDES; CELL LINE, TRANSFORMED; CELL SURVIVAL; DNA; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; HUMANS; IMIDAZOLES; NANOPARTICLES; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS; TRANSFECTION;

EID: 77951498391     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.01.005     Document Type: Article

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