Evaluation of the antifungal and plasma membrane H+-ATPase inhibitory action of ebselen and two ebselen analogs in S. cerevisiae cultures

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 3, 2010, Pages 312-317

  Billack, Blase ^a   Pietka Ottlik, Magdalena ^b   Santoro, Michelle ^a   Nicholson, Stacia ^a   Młochowski, Jacek ^b   Lau Cam, Cesar ^a  

^a ST JOHN'S UNIVERSITY   (United States)

^b WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Antifungal activity; Benzisoselenazol 3(2H) ones; Ebselen; Pma1p; Saccharomyces cerevisiae

Indexed keywords

2 (3 PYRIDINYL)BENZISOSELENAZOL 3(2H) ONE; 2 PHENYLBENZISOSELENAZOL 3(2H) ONE 1 OXIDE; ANTIFUNGAL AGENT; CYSTEINE; EBSELEN; FUNGAL ENZYME; MEMBRANE ENZYME; ORGANOSELENIUM DERIVATIVE; PROTON PUMP; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; ENZYME INHIBITION; FUNGUS CULTURE; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY;

ANTIFUNGAL AGENTS; AZOLES; ORGANOSELENIUM COMPOUNDS; PROTON-TRANSLOCATING ATPASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 77951471245     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360903179419     Document Type: Article

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