The need for precompetitive integrative bionetwork disease model building

Clinical Pharmacology and Therapeutics

Volumn 87, Issue 5, 2010, Pages 536-539

  Friend, S H ^a  

^a SAGE BIONETWORKS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DNA; RNA;

DISEASE MODEL; DRUG TARGETING; GENE MUTATION; HUMAN; IN VITRO STUDY; NOTE; PATIENT CARE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ANIMALS; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; GENE REGULATORY NETWORKS; HUMANS; MODELS, GENETIC; SYSTEMS BIOLOGY; THERAPIES, INVESTIGATIONAL;

EID: 77951454093     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2010.40     Document Type: Note

References (4)

1. Mathieu, R.G. IT systems perspective: top-down approach to computing. IEEE Computer 35, 138-139 (2002).
2. Schadt, E.E., Friend, S.H. & Shaywitz, D.A. A network view of disease and compound screening. Nat. Rev. Drug Discov. 8, 286-295 (2009).
3. Waters, K.M., Singhal, M., Webb-Robertson, B.J.M., Stephan, E.G., & Gephart, J.M. Breaking the high-throughput bottleneck: new tools help biologists integrate complex datasets. Sci. Comput. 23, 22-26 (2006)
4. Winning through cooperation: An interview with William Spencer. Technol. Rev. 100, 22-27 http://www.technologyreview.com/computing/11501/(1997).