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Volumn 116, Issue 9, 2010, Pages 2208-2214

The cisplatin, epirubicin, 5-fluorouracil, gemcitabine (PEFG) regimen in advanced biliary tract adenocarcinoma

Author keywords

5 fluorouracil; Biliary tract cancer; Chemotherapy; Cisplatin; Epirubicin; Gemcitabine; PEFG regimen

Indexed keywords

CISPLATIN; CISPLATINO; EPIRUBICIN; ERYTHROPOIETIN; FARMARUBICINA; FLUOROURACIL; FLUOROURACILE; GEMCITABINE; GROWTH FACTOR; UNCLASSIFIED DRUG;

EID: 77951430103     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24970     Document Type: Article
Times cited : (34)

References (46)
  • 3
    • 0021195794 scopus 로고
    • Eastern Cooperative Oncology Group experience with chemotherapy for inoperable gallbladder and bile duct cancer
    • Falkson G, Macintyre JM, Moertel CG. Eastern Cooperative Oncology Group experience with chemotherapy for inoperable gallbladder and bile duct cancer. Cancer. 1984;54:965-969. (Pubitemid 14069807)
    • (1984) Cancer , vol.54 , Issue.6 , pp. 965-969
    • Falkson, G.1    MacIntyre, J.M.2    Moertel, C.G.3
  • 4
    • 0027935148 scopus 로고
    • Comparison of 5-fluorouracil, doxorubicin and mitomycin C with 5-fluorouracil alone in the treatment of pancreatic-biliary carcinomas
    • Takada T, Kato H, Matsushiro T, et al. Combination of 5-fluorouracil, doxorubicin and mitomycin C with 5-fluorouracil alone in the treatment of pancreatic-biliary carcinomas. Oncology. 1994;51:396-400. (Pubitemid 24255303)
    • (1994) Oncology , vol.51 , Issue.5 , pp. 396-400
    • Takada, T.1    Kato, H.2    Matsushiro, T.3    Nimura, Y.4    Nagakawa, T.5    Nakayama, T.6
  • 5
    • 0028214029 scopus 로고
    • Epirubicin-sequential methotrexate-5-fluorouracil-leucovorin treatment in advanced cancer of the extrahepatic biliary system: A phase II study
    • Kajanti M, Phyronen S. Epirubicin-sequential methotrexate-5-fluorouracil- leucovorin treatment in advanced cancer of the extrahepatic biliary system. A phase II study. Am J Clin Oncol. 1994;17:223-226. (Pubitemid 24160612)
    • (1994) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.17 , Issue.3 , pp. 223-226
    • Kajanti, M.1    Pyrhonen, S.2
  • 7
    • 0015994243 scopus 로고
    • Adenocarcinomas of stomach, pancreas, liver, and biliary tract. Survival of 328 patients treated with fluoropyrimidine therapy
    • Davis HL Jr, Ramirez G, Ansfield FJ. Adenocarcinomas of stomach, pancreas, liver, and biliary tract. Survival of 328 patients treated with fluoropyrimidine therapy. Cancer. 1974;33:193-197.
    • (1974) Cancer , vol.33 , pp. 193-197
    • Davis Jr., H.L.1    Ramirez, G.2    Ansfield, F.J.3
  • 9
    • 33745970752 scopus 로고    scopus 로고
    • Phase II study of erlotinib in patients with advanced biliary cancer
    • Philip PA, Mahoney MR, Allmer C, et al. Phase II study of erlotinib in patients with advanced biliary cancer. J Clin Oncol. 2006;24:3069-3073.
    • (2006) J Clin Oncol , vol.24 , pp. 3069-3073
    • Philip, P.A.1    Mahoney, M.R.2    Allmer, C.3
  • 10
    • 19944433180 scopus 로고    scopus 로고
    • A randomised phase II trial of weekly high-dose 5-fluorouracil with and without folinic acid and cisplatin in patients with advanced biliary tract carcinoma: Results of the 40955 EORTC trial
    • DOI 10.1016/j.ejca.2004.10.026, PII S0959804904009724
    • Ducreux M, Van Cutsem E, Van Laethem JL, et al. A randomised phase II trial of weekly high-dose 5-fluorouracil with and without folinic acid and cisplatin in patients with advanced biliary tract carcinoma: results of the 40955 EORTC trial. Eur J Cancer. 2005;41:398-403. (Pubitemid 40187211)
    • (2005) European Journal of Cancer , vol.41 , Issue.3 , pp. 398-403
    • Ducreux, M.1    Van Cutsem, E.2    Van Laethem, J.L.3    Gress, T.M.4    Jeziorski, K.5    Rougier, P.6    Wagener, T.7    Anak, O.8    Baron, B.9    Nordlinger, B.10
  • 12
    • 49749136654 scopus 로고    scopus 로고
    • S1 monotherapy as first-line treatment in patients with advanced biliary tract cancer: A multicenter phase II study
    • Furuse J, Okusaka T, Boku N, et al. S1 monotherapy as first-line treatment in patients with advanced biliary tract cancer: a multicenter phase II study. Cancer Chemother Pharmacol. 2008;62:849-855.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 849-855
    • Furuse, J.1    Okusaka, T.2    Boku, N.3
  • 15
    • 0037971057 scopus 로고    scopus 로고
    • CPT-11 for bileduct and gallbladder carcinoma: A phase II North Central Cancer Treatment Group (NCCTG) study
    • Alberts SR, Fishkin PA, Burgart LJ, et al. CPT-11 for bileduct and gallbladder carcinoma: a phase II North Central Cancer Treatment Group (NCCTG) study. Int J Gastrointest Cancer. 2002;32:107-114.
    • (2002) Int J Gastrointest Cancer , vol.32 , pp. 107-114
    • Alberts, S.R.1    Fishkin, P.A.2    Burgart, L.J.3
  • 16
    • 0027182199 scopus 로고
    • Phase II trial of mitomycin C (MMC) in advanced gallbladder and biliary tree carcinoma
    • An EORTC Gastrointestinal Tract Cancer Cooperative Group study
    • Taal BG, Audisio RA, Bleiberg H, et al. Phase II trial of mitomycin C (MMC) in advanced gallbladder and biliary tree carcinoma. An EORTC Gastrointestinal Tract Cancer Cooperative Group study. Ann Oncol. 1993;4:607-609.
    • (1993) Ann Oncol , vol.4 , pp. 607-609
    • Taal, B.G.1    Audisio, R.A.2    Bleiberg, H.3
  • 17
    • 33947387077 scopus 로고    scopus 로고
    • Chemotherapy in advanced biliary tract carcinoma: A pooled analysis of clinical trials
    • DOI 10.1038/sj.bjc.6603648, PII 6603648
    • Eckel F, Schmid RM. Chemotherapy in advanced biliary tract carcinoma: a pooled analysis of clinical trials. Br J Cancer. 2007;96:896-902. (Pubitemid 46452283)
    • (2007) British Journal of Cancer , vol.96 , Issue.6 , pp. 896-902
    • Eckel, F.1    Schmid, R.M.2
  • 18
    • 0000667228 scopus 로고    scopus 로고
    • Synergistic interaction of gemcitabine and 5-fluorouracil in colon cancer cells
    • abstract. Abstract 965
    • Schulz L, Schalhorn W, Wilmanns W, et al. Synergistic interaction of gemcitabine and 5-fluorouracil in colon cancer cells [abstract]. Proc Am Soc Clin Oncol. 1998;17:251a. Abstract 965.
    • Proc Am Soc Clin Oncol 1998 , vol.17 , pp. 251
    • Schulz, L.1    Schalhorn, W.2    Wilmanns, W.3
  • 19
    • 0012196868 scopus 로고    scopus 로고
    • Antitumor activity of combination therapy with capecitabine plus vinorelbine, and capecitabine plus gemcitabine in human tumor xenograft models
    • abstract. Abstract 5388
    • Sawada N, Fujimoto-Ouchi K, Ishikawa T, et al. Antitumor activity of combination therapy with capecitabine plus vinorelbine, and capecitabine plus gemcitabine in human tumor xenograft models [abstract]. Proc Am Assoc Cancer Res. 2002;43:1088. Abstract 5388.
    • Proc Am Assoc Cancer Res 2002 , vol.43 , pp. 1088
    • Sawada, N.1    Fujimoto-Ouchi, K.2    Ishikawa, T.3
  • 21
    • 0021717017 scopus 로고
    • 5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract
    • Harvey JH, Smith FP, Schein PS. 5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract. J Clin Oncol. 1984;2:1245-1248.
    • (1984) J Clin Oncol. , vol.2 , pp. 1245-1248
    • Harvey, J.H.1    Smith, F.P.2    Schein, P.S.3
  • 23
    • 0032526183 scopus 로고    scopus 로고
    • A phase II trial of 5-fluorouracil, leucovorin, and carboplatin in patients with unresectable biliary tree carcinoma
    • DOI 10.1002/(SICI)1097-0142(19980615)82:12<2321::AID-CNCR4>3.0. CO;2-V
    • Sanz-Altamira P, Ferrante K, Jenkins R, et al. A phase II trial of 5-FU leucovorin and carboplatin in patients with unresectable biliary tree carcinoma. Cancer. 1998;82:2321-2325. (Pubitemid 28283437)
    • (1998) Cancer , vol.82 , Issue.12 , pp. 2321-2325
    • Sanz-Altamira, P.M.1    Ferrante, K.2    Jenkins, R.L.3    Lewis, W.D.4    Huberman, M.S.5    Stuart, K.E.6
  • 24
    • 0035186224 scopus 로고    scopus 로고
    • Phase II trial of cisplatin, interferon a-2b, doxorubicin, and fluorouracil for biliary tract cancer
    • Patt YZ, Haasan MM, Lozano RD, et al. Phase II trial of cisplatin, interferon a-2b, doxorubicin, and fluorouracil for biliary tract cancer. Clin Cancer Res. 2001;7:3375-3380.
    • (2001) Clin Cancer Res , vol.7 , pp. 3375-3380
    • Patt, Y.Z.1    Haasan, M.M.2    Lozano, R.D.3
  • 25
    • 0028862265 scopus 로고
    • Epirubicin, cisplatin and infusional 5-fluorouracil (5-FU) (ECF) in hepatobiliary tumors
    • Ellis PA, Norman A, Hill A, et al. Epirubicin, cisplatin and infusional 5-fluorouracil (5-FU) (ECF) in hepatobiliary tumors. Eur J Cancer. 1995;31:1594-1598.
    • (1995) Eur J Cancer , vol.31 , pp. 1594-1598
    • Ellis, P.A.1    Norman, A.2    Hill, A.3
  • 26
    • 0036668659 scopus 로고    scopus 로고
    • Optimization of 5-fluorouracil (5-FU)/cisplatin combination chemotherapy with a new schedule of leucovorin, 5-FU and cisplatin (LV5FU2-P regimen) in patients with biliary tract carcinoma
    • DOI 10.1093/annonc/mdf201
    • Taieb J, Mitry E, Boige V, et al. Optimization of 5-fluorouracil (5-FU)/cisplatin combination chemotherapy with a new schedule of leucovorin, 5-FU and cisplatin (LV5FU2-P regimen) in patients with biliary tract carcinoma. Ann Oncol. 2002;13:1192-1196. (Pubitemid 34960126)
    • (2002) Annals of Oncology , vol.13 , Issue.8 , pp. 1192-1196
    • Ducreux, M.1    Taieb, J.2    Mitry, E.3    Boige, V.4    Artru, P.5    Ezenfis, J.6    Lecomte, T.7    Clavero-Fabri, M.C.8    Vaillant, J.N.9    Rougier, P.10
  • 28
    • 14644410398 scopus 로고    scopus 로고
    • Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma
    • DOI 10.1093/annonc/mdi046
    • Thongprasert S, Napapan S, Charoentum C, et al. Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma. Ann Oncol. 2005;6:279-281. (Pubitemid 40309310)
    • (2005) Annals of Oncology , vol.16 , Issue.2 , pp. 279-281
    • Thongprasert, S.1    Napapan, S.2    Charoentum, C.3    Moonprakan, S.4
  • 30
    • 2642567052 scopus 로고    scopus 로고
    • Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: A review of the Princess Margaret Hospital experience
    • DOI 10.1093/annonc/mdh172
    • Knox JJ, Hedley D, Oza A, et al. Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: a review of the Princess Margaret Hospital experience. Ann Oncol. 2004;15:770-774. (Pubitemid 38714738)
    • (2004) Annals of Oncology , vol.15 , Issue.5 , pp. 770-774
    • Knox, J.J.1    Hedley, D.2    Oza, A.3    Siu, L.L.4    Pond, G.R.5    Moore, M.J.6
  • 31
    • 10844226636 scopus 로고    scopus 로고
    • Gemcitabine, 5-fluorouracil, and leucovorin in advanced biliary tract and gallbladder carcinoma
    • Alberts SR, Al-Khatib H, Mahoney MR, et al. Gemcitabine, 5-fluorouracil, and leucovorin in advanced biliary tract and gallbladder carcinoma. Cancer. 2005;103:111-118.
    • (2005) Cancer , vol.103 , pp. 111-118
    • Alberts, S.R.1    Al-Khatib, H.2    Mahoney, M.R.3
  • 33
    • 1842555346 scopus 로고    scopus 로고
    • Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: A randomised phase II trial
    • DOI 10.1093/annonc/mdh096
    • Kornek GV, Schuell B, Laengle F, et al. Mitomycin C in combination with capecitabine or bi-weekley high-dose gemcitabine in patients with advanced biliary tract cancer: a randomised phase II trial. Ann Oncol. 2004;15:478-483. (Pubitemid 38444553)
    • (2004) Annals of Oncology , vol.15 , Issue.3 , pp. 478-483
    • Kornek, G.V.1    Schuell, B.2    Laengle, F.3    Gruenberger, T.4    Penz, M.5    Karall, K.6    Depisch, D.7    Lang, F.8    Scheithauer, W.9
  • 34
    • 30744449247 scopus 로고    scopus 로고
    • Phase II study of epirubicin, cisplatin, and capecitabine for advanced biliary tract adenocarcinoma
    • DOI 10.1002/cncr.21621
    • Park SH, Park JH, Lee JN, et al. Phase II study of epirubicin, cisplatin, and capecitabine for advanced biliary tract adenocarcinoma. Cancer. 2006;106:361-365. (Pubitemid 43100445)
    • (2006) Cancer , vol.106 , Issue.2 , pp. 361-365
    • Park, S.H.1    Park, Y.H.2    Lee, J.N.3    Bang, S.-M.4    Cho, E.K.5    Shin, D.B.6    Lee, J.H.7
  • 35
    • 0038312231 scopus 로고    scopus 로고
    • Phase II study of cisplatin, epirubicin, and continuous-infusion 5-fluorouracil for advanced biliary tract cancer
    • DOI 10.1159/000070310
    • Morizane C, Okada S, Okusaka T, et al. Phase II study of cisplatin, epirubicin, and continuous-infusion 5-fluorouracil for advanced biliary tract cancer. Oncology. 2003;64:475-476. (Pubitemid 36682965)
    • (2003) Oncology , vol.64 , Issue.4 , pp. 475-476
    • Morizane, C.1    Okada, S.2    Okusaka, T.3    Ueno, H.4    Saisho, T.5
  • 36
    • 19944380109 scopus 로고    scopus 로고
    • Phase III study of 5FU, etoposide and leucovorin (FELV) compared to epirubicin, cisplatin and 5FU (ECF) in previously untreated patients with advanced biliary cancer
    • DOI 10.1038/sj.bjc.6602576
    • Rao S, Cunningham D, Hawkins RE, et al. Phase III study of 5FU, etoposide and leucovorin (FELV) compared with epirubicin, cisplatin and 5FU (ECF) in previously untreated patients with advanced biliary cancer. Br J Cancer. 2005;92:1650-1654. (Pubitemid 40756474)
    • (2005) British Journal of Cancer , vol.92 , Issue.9 , pp. 1650-1654
    • Rao, S.1    Cunningham, D.2    Hawkins, R.E.3    Hill, M.E.4    Smith, D.5    Daniel, F.6    Ross, P.J.7    Oates, J.8    Norman, A.R.9
  • 37
    • 3042844291 scopus 로고    scopus 로고
    • Epirubicin, cisplatin, and protracted infusion of 5-FU (ECF) in advanced intrahepatic cholangiocarcinoma
    • Lee MA, Woo IS, Kang JH, et al. Epirubicin, cisplatin, and protracted infusion of 5-FU (ECF) in advanced intrahepatic cholangiocarcinoma. J Cancer Res Clin Oncol. 2004;130:346-350.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 346-350
    • Lee, M.A.1    Woo, I.S.2    Kang, J.H.3
  • 38
    • 19944409357 scopus 로고    scopus 로고
    • Gemcitabine versus cisplatin, epirubicin, 5-fluorouracil, gemcitabine in advanced pancreatic cancer: A phase III trial
    • Reni M, Cordio S, Milandri C, et al. Gemcitabine versus cisplatin, epirubicin, 5-fluorouracil, gemcitabine in advanced pancreatic cancer: a phase III trial. Lancet Oncol. 2005;6:369-376.
    • (2005) Lancet Oncol , vol.6 , pp. 369-376
    • Reni, M.1    Cordio, S.2    Milandri, C.3
  • 40
    • 0003486931 scopus 로고
    • World Health Organization (WHO). WHO Offset Publication No. 48. Geneva, Switzerland: WHO
    • World Health Organization (WHO). WHO Handbook for Reporting Results of Cancer Treatment. WHO Offset Publication No. 48. Geneva, Switzerland: WHO; 1979.
    • (1979) WHO Handbook for Reporting Results of Cancer Treatment
  • 41
    • 0025195396 scopus 로고
    • Comprehensive criteria for assessing therapy-induced toxicity
    • Ajani JA, Welch SR, Raber MN, et al. Comprehensive criteria for assessing therapy-induced toxicity. Cancer Invest. 1990;8:147-159.
    • (1990) Cancer Invest , vol.8 , pp. 147-159
    • Ajani, J.A.1    Welch, S.R.2    Raber, M.N.3
  • 42
    • 67649220204 scopus 로고    scopus 로고
    • Carbohydrate antigen 19-9 change during chemotherapy for advanced pancreatic adenocarcinoma
    • Reni M, Cereda S, Balzano G, et al. Carbohydrate antigen 19-9 change during chemotherapy for advanced pancreatic adenocarcinoma. Cancer. 2009;115:2630-2639.
    • (2009) Cancer , vol.115 , pp. 2630-2639
    • Reni, M.1    Cereda, S.2    Balzano, G.3
  • 45
    • 67649174014 scopus 로고    scopus 로고
    • A randomized phase II trial of PEXG (cisplatin, epirubicin, capecitabine, gemcitabine) or PDXG (docetaxel) regimen in advanced pancreatic adenocarcinoma
    • ASCO Annual Meeting Proceedings, Part I [abstract]. Abstract 4628
    • Reni M, Cereda S, Passoni P, et al. A randomized phase II trial of PEXG (cisplatin, epirubicin, capecitabine, gemcitabine) or PDXG (docetaxel) regimen in advanced pancreatic adenocarcinoma. ASCO Annual Meeting Proceedings, Part I [abstract]. J Clin Oncol. 2007;25(18S). Abstract 4628.
    • (2007) J Clin Oncol. , vol.25 , Issue.18 S
    • Reni, M.1    Cereda, S.2    Passoni, P.3
  • 46
    • 21244437063 scopus 로고    scopus 로고
    • Report of two protocol planned interim analyses in a randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric cancer receiving ECF
    • DOI 10.1038/sj.bjc.6602572
    • Sumpter K, Harper-Wynne C, Cunningham D, et al. Report of 2 protocol planned interim analyses in a randomised, multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophago-gastric cancer receiving ECF. Br J Cancer. 2005;92:1976-1983. (Pubitemid 40897418)
    • (2005) British Journal of Cancer , vol.92 , Issue.11 , pp. 1976-1983
    • Sumpter, K.1    Harper-Wynne, C.2    Cunningham, D.3    Rao, S.4    Tebbutt, N.5    Norman, A.R.6    Ward, C.7    Iveson, T.8    Nicolson, M.9    Hickish, T.10    Hill, M.11    Oates, J.12


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