Are PALB2 mutations associated with increased risk of male breast cancer?

Breast Cancer Research and Treatment

Volumn 121, Issue 1, 2010, Pages 253-255

  Sauty De Chalon, A ^a,b   Teo, Z ^a   Park, D J ^a   Odefrey, F A ^a   KConFab, ^c   Hopper, J L ^a   Southey, M C ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITÉ CATHOLIQUE DE LYON   (France)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PALB2 PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ADULT; AGED; AMINO ACID SUBSTITUTION; BREAST CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CLINICAL ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; GERMLINE MUTATION; HUMAN; LETTER; MALE; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PEDIGREE ANALYSIS; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; BREAST NEOPLASMS, MALE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PEDIGREE; RISK FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 77951297062     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0673-x     Document Type: Letter

References (10)

1. Ottini L, Palli D, Rizzo S, Federico M, Bazan V, Russo A (2009) Male breast cancer. Crit Rev Oncol Hematol. doi: 10.1016/j.critrevonc.2009.04.003
2. AM Woodward TA Davis AG Silva JA Kirk JA Leary kConFab Investigators 2005 kConFab Investigators. Large genomic rearrangements of both BRCA2 and BRCA1 are a feature of the inherited breast/ovarian cancer phenotype in selected families J Med Genet 42 5 e31 10.1136/jmg.2004.027961 1:STN:280:DC%2BD2M3ivFSrug%3D%3D 15863663
3. GJ Mann H Thorne RL Balleine PN Butow CL Clarke E Edkins GM Evans S Fereday E Haan M Gattas GG Giles J Goldblatt JL Hopper J Kirk JA Leary G Lindeman E Niedermayr KA Phillips S Picken GM Pupo C Saunders CL Scott AB Spurdle G Suthers K Tucker G Chenevix-Trench 2006 Kathleen Cunningham Consortium for Research in Familial Breast Cancer. Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource Breast Cancer Res 8 1 R12 10.1186/bcr1377 16507150 Epub 2006 Feb 13 (Pubitemid 44644827)
4. N Rahman S Seal D Thompson P Kelly A Renwick A Elliott S Reid K Spanova R Barfoot T Chagtai H Jayatilake L McGuffog S Hanks DG Evans D Eccles 2007 Breast Cancer Susceptibility Collaboration (UK), Easton DF, Stratton MR.PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene Nat Genet 39 2 165 167 10.1038/ng1959 1:CAS:528:DC%2BD2sXpvFeqsw%3D%3D 17200668 Epub 2006 Dec 31 (Pubitemid 46184346)
5. MJ García V Fernández A Osorio A Barroso G Llort C Lázaro I Blanco T Caldés M de la Hoya Y Ramón T Cajal C Alonso MI Tejada C San Román L Robles-Díaz M Urioste J Benítez 2009 Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families Breast Cancer Res Treat 113 3 545 551 10.1007/s10549-008-9945-0 18302019 Epub 2008 Feb 27
6. H Erkko B Xia J Nikkilä J Schleutker K Syrjäkoski A Mannermaa A Kallioniemi K Pylkäs SM Karppinen K Rapakko A Miron Q Sheng G Li H Mattila DW Bell DA Haber M Grip M Reiman A Jukkola-Vuorinen A Mustonen J Kere LA Aaltonen VM Kosma V Kataja Y Soini RI Drapkin DM Livingston R Winqvist 2007 A recurrent mutation in PALB2 in Finnish cancer families Nature 446 7133 316 319 10.1038/nature05609 1:CAS:528:DC%2BD2sXivVSns78%3D 17287723 Epub 2007 Feb 7 (Pubitemid 46426155)
7. WD Foulkes P Ghadirian MR Akbari N Hamel S Giroux N Sabbaghian A Darnel R Royer A Poll E Fafard A Robidoux G Martin TA Bismar M Tischkowitz F Rousseau SA Narod 2007 Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women Breast Cancer Res 9 6 R83 10.1186/bcr1828 18053174
8. AC Antoniou PD Pharoah S Narod HA Risch JE Eyfjord JL Hopper H Olsson O Johannsson A Borg B Pasini P Radice S Manoukian DM Eccles N Tang E Olah H Anton-Culver E Warner J Lubinski J Gronwald B Gorski H Tulinius S Thorlacius H Eerola H Nevanlinna K Syrjäkoski OP Kallioniemi D Thompson C Evans J Peto F Lalloo DG Evans DF Easton 2005 Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies J Med Genet 42 7 602 603 10.1136/jmg.2004.024133 1:CAS:528:DC%2BD2MXnsVehsbs%3D 15994883 (Pubitemid 40993838)
9. GB Byrnes MC Southey JL Hopper 2008 Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories? Breast Cancer Res 10 3 208 10.1186/bcr2099 18557994 Epub 2008 Jun 5. Review
10. RH Vossen E Aten A Roos JT den Dunnen 2009 High-resolution melting analysis (HRMA): more than just sequence variant screening Hum Mutat 30 6 860 866 10.1002/humu.21019 1:CAS:528:DC%2BD1MXpt1Sht74%3D 19418555 Review