ARTICLE;
CHEMICAL REACTION;
DEHYDROGENATION;
DRUG IDENTIFICATION;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TRANSFORMATION;
REACTION TIME;
ROOM TEMPERATURE;
TEMPERATURE SENSITIVITY;
First total synthesis of 25(R)-ruscogenin-1-yl β-d-xylopyranosyl-(1 → 3)-[β-d-glucopyranosyl-(1 → 2)]-β-d-fucopyranoside, an ophiopogonis saponin from the tuber of Liriope muscari (decne.)
Liu M., Yu B., and Hui Y. First total synthesis of 25(R)-ruscogenin-1-yl β-d-xylopyranosyl-(1 → 3)-[β-d-glucopyranosyl-(1 → 2)]-β-d-fucopyranoside, an ophiopogonis saponin from the tuber of Liriope muscari (decne.). Tetrahedron Lett 39 (1998) 415
Synthesis of (20R)- and (20S)-1α,3β-diacetoxypregna-5,7-dien-20-ol and 1α,3β-diacetoxyandrosta-5,7-dien-17β-ol
Tachibana Y. Synthesis of (20R)- and (20S)-1α,3β-diacetoxypregna-5,7-dien-20-ol and 1α,3β-diacetoxyandrosta-5,7-dien-17β-ol. Chem Pharm Bull 42 (1994) 2215
Oxidation of trialkylsilyl enol ethers via hydride abstraction: a new procedure for ketone to enone conversion
Jung M.E., Pan Y.G., Rathke M.W., Sullivan D.F., and Woodbury R.P. Oxidation of trialkylsilyl enol ethers via hydride abstraction: a new procedure for ketone to enone conversion. J Org Chem 42 (1977) 3961
A samarium(II) iodine promoted tandem radical cyclization. The total synthesis of (±)hypnophilin and the formal synthesis of (±)-coriolin
Fevig T.L., Elliott R.L., and Curran D.P. A samarium(II) iodine promoted tandem radical cyclization. The total synthesis of (±)hypnophilin and the formal synthesis of (±)-coriolin. J Am Chem Soc 110 (1988) 5064-5067
3 solution was used for the synthesis of boldenone propionate (Table 2, entry 6).
17
67949085287
1,2-Dehydrogenation of steroidal 6-methylen derivatives. Synthesis of exemestane
1-dehydrogenation procedure of 1f for the synthesis exemestane 2f by using chloranil and excess BSTFA (4.2 equiv.) in the presence of triflic acid in refluxing toluene. See Ref.
1-dehydrogenation procedure of 1f for the synthesis exemestane 2f by using chloranil and excess BSTFA (4.2 equiv.) in the presence of triflic acid in refluxing toluene. See Ref. Marcos-Escribano A., Bermejo F.A., Bonde-Larsen A.L., Retuerto A.I., and Sierra IH. 1,2-Dehydrogenation of steroidal 6-methylen derivatives. Synthesis of exemestane. Tetrahedron 65 (2009) 7587-7590
Silylation-mediated oxidation of 4-aza-3-ketosteroids with DDQ proceeds via DDQ-substrate adducts
Bhattacharya A., DiMichele L.M., Dolling U., Douglas A.W., and Grabowski E.J.J. Silylation-mediated oxidation of 4-aza-3-ketosteroids with DDQ proceeds via DDQ-substrate adducts. J Am Chem Soc 110 (1988) 3318-3319
