Efficacy of a chimeric PCV2 vaccine: A field trial

Thai Journal of Veterinary Medicine

Volumn 39, Issue 2, 2009, Pages 145-155

  Paphavasit, Termsitthi ^a   Lehrbach, Philip ^b   Navasakuljinda, Wichian ^b   Kedkovid, Roongtham ^a   Lacharoje, Sitthichok ^a   Thanawongnuwech, Roongroje ^a   Teankum, Komkrich ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b Fort Dodge Animal Health ^*  (Thailand)

Author keywords

Chimeric vaccine; Efficacy; Lesion; Porcine circovirus type 2; Viremia

Indexed keywords

ANIMALIA; CIRCOVIRUS; PORCINE CIRCOVIRUS 2; SUIDAE;

EID: 77951262675     PISSN: 01256491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Allan, G.M. and Ellis, J.A. 2000. Porcine circoviruses: a review. J. Vet. Diagn. Invest. 12: 3-14.
2. th International Pig Veterinary Congress (IPVS) June 2-5, 2002. Ames, Iowa, USA. 469.
3. Chae, C. 2005. A review of porcine circovirus 2-associated syndromes and diseases. Vet. J. 169: 326-336.
4. Connor, J. and Elsener, J. 2007. Field efficacy of Suvaxyn® PCV2 one dose in pigs. Proceeding of the annual meeting of the American Association of Swine Veterinarians, Florida, USA. 151-152.
5. Darwich, L., Segales, J. and Mateu, E. 2004. Pathogenesis of postweaning multisystemic wasting syndrome caused by porcine circovirus 2: an immune riddle. Arch. Virol. 149: 857-574.
6. Fenaux, M., Opriessnig, T., Halbur, P.G., Elvinger, F. and Meng, X.J. 2004. A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV-2) cloned into the genomic backbone of the non-pathogenic PCV1 induces protective immunity against PCV2 infection in pigs. J. Virol. 78: 6297-6303.
7. Halbur, P.G., Paul, P.S., Frey, M.L., Landgraf, J., Eernisse, K., Meng, X.J., Lum, M.A., Andrews, J.J. and Rathje, J.A. 1995. Comparison of the pathogenicity of two U.S. porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 32: 648-660.
8. Mankertz, A., Caliskan, R., Hattermann, K., Hillenbrand, B., Kurzendoerfer, P., Mueller, B., Schmitt, C., Steinfeldt, T. and Finsterbusch, T. 2004. Molecular biology of porcine circovirus: analyses of gene expression and viral replication. Vet. Microbiol. 98: 81-88.
9. McIntosh, K.A., Harding, J.C., Ellis, J.A., Appleyard, G.D. 2006. Detection of porcine circovirus type 2 viremia and seroconversion in naturally infected pigs in a farrow-to-finish barn. Can. J. Vet. Res. 70: 58-61.
10. McKeown, N.E., Opriessnig, T., Thomas, P., Guenette, D.K., Elvinger, F., Fenaux, M., Halbur, P.G., and Meng, X.J. 2005. Effects of porcine circovirus type 2 (PCV2) maternal antibodies on experimental infection of piglets with PCV2. Clin. Diagn. Lab. Immunol. 12: 1347-1351.
11. Opriessnig, T., Meng, X.J. and Halbur, P.G. 2007. Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies. J. Vet. Diagn. Invest. 19: 591-615.
12. Opriessnig, T., Patterson, A.R., Elsener, J., Meng, X.J. and Halbur, P.G. 2008. Influence of maternal antibodies on efficacy of porcine circovirus type 2 (PCV2) vaccination to protect pigs from experimental infection with PCV2. Clin. Vaccine Immunol. 15: 397-401.
13. Segales, J., Rosell, C. and Domingo, M. 2004. Pathological findings associated with naturally acquired porcine circovirus type 2 associated disease. Vet. Microbiol. 98: 137-149.
14. thed. B.E. Straw, S.D. Allaries, W.L. Mengeling, and D.J. Taylor (eds.). Ames, Iowa State University Press. 3-5.
15. Thanawongnuwech, R., Thacker, B., Halbur, P. and Thacker, E.L. 2004. Increased production of proinflammatory cytokines following infection with porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae. Clin. Diagn. Lab. Immunol. 11: 901-908.
16. th International Pig Veterinary Congress (IPVS), Copenhagen, Denmark, Vol. 2. 108.