Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice

Development

Volumn 137, Issue 8, 2010, Pages 1285-1295

  Qu, Xianghu ^a   Tompkins, Kevin ^a   Batts, Lorene E ^a   Puri, Mira ^b   Baldwin, Scott ^a,c  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Hypomorphic; Lymphatic development; Mouse; Proliferation; Tie1

Indexed keywords

TIE 1 RECEPTOR; PRIMER DNA; PROTEIN TYROSINE KINASE; TIE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; GENE FREQUENCY; LYMPHANGIOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; ANIMAL; BLOOD VESSEL; DNA PROBE; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; LYMPHATIC SYSTEM; MOUSE MUTANT; PHENOTYPE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PRENATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MUS;

ANIMALS; APOPTOSIS; BLOOD VESSELS; DNA PRIMERS; DNA PROBES; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; LYMPHANGIOGENESIS; LYMPHATIC SYSTEM; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; PHENOTYPE; POLYMERASE CHAIN REACTION; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, TIE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77951231374     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.043380     Document Type: Article

References (50)

1. Ayadi, A., Zheng, H., Sobieszczuk, P., Buchwalter, G., Moerman, P., Alitalo, K. and Wasylyk, B. (2001). Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 20, 5139-5152. (Pubitemid 32910909)
2. Buttler, K., Kreysing, A., von Kaisenberg, C. S., Schweigerer, L., Gale, N., Papoutsi, M. and Wilting, J. (2006). Mesenchymal cells with leukocyte and lymphendothelial characteristics in murine embryos. Dev. Dyn. 235, 1554-1562. (Pubitemid 43787957)
3. Buttler, K., Ezaki, T. and Wilting, J. (2008). Proliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristics. BMC Dev. Biol. 8, 43. (Pubitemid 351678107)
4. Dellinger, M., Hunter, R., Bernas, M., Gale, N., Yancopoulos, G., Erickson, R. and Witte, M. (2008). Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice. Dev. Biol. 319, 309-320.
5. Dumont, D. J., Fong, G. H., Puri, M. C., Gradwohl, G, Alitalo, K. and Breitman, M. L. (1995). Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev. Dyn. 203, 80-92.
6. Eklund, L. and Olsen, B. R. (2006). Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp. Cell Res. 312, 630-641. (Pubitemid 43290339)
7. François, M., Caprini, A., Hosking, B., Orsenigo, F., Wilhelm, D., Browne, C., Paavonen, K., Karnezis, T., Shayan, R., Downes, M. et al. (2008). Sox18 induces development of the lymphatic vasculature in mice. Nature 456, 643-647.
8. Fritz-Six, K. L., Dunworth, W. P., Li, M. and Caron, K. M. (2008). Adrenomedullin signaling is necessary for murine lymphatic vascular development. J. Clin. Invest. 118, 40-50.
9. Gale, N. W., Thurston, G., Hackett, S. F., Renard, R., Wang, Q., McClain, J., Martin, C., Witte, C., Witte, M. H., Jackson, D. et al. (2002). Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. Dev. Cell 3, 411-423.
10. Gittenberger-De Groot, A. C., Van Den Akker, N. M., Bartelings, M. M., Webb, S., Van Vugt, J. M. and Haak, M. C. (2004). Abnormal lymphatic development in trisomy 16 mouse embryos precedes nuchal edema. Dev. Dyn. 230, 378-384. (Pubitemid 38669599)
11. Hashiyama, M., Iwama, A., Ohshiro, K., Kurozumi, K., Yasunaga, K., Shimizu, Y., Masuho, Y., Matsuda, I., Yamaguchi, N. and Suda, T. (1996). Predominant expression of a receptor tyrosine kinase, TIE, in hematopoietic stem cells and B cells. Blood 87, 93-101. (Pubitemid 26011823)
12. Hirashima, M., Sano, K., Morisada, T., Murakami, K., Rossant, J. and Suda, T. (2008). Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev. Biol. 316, 149-159.
13. Hosking, B., François, M., Wilhelm, D., Orsenigo, F., Caprini, A., Svingen, T., Tutt, D., Davidson, T., Browne, C., Dejana, E. et al. (2009). Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice. Development 136, 2385-2391.
14. Huang, X. Z., Wu, J. F., Ferrando, R., Lee, J. H., Wang, Y. L. et al. (2000). Fatal bilateral chylothorax in mice lacking the integrin a9b1. Mol. Cell. Biol. 20, 5208-5215. (Pubitemid 30431573)
15. Iljin, K., Petrova, T. V., Veikkola, T., Kumar, V., Poutanen, M. and Alitalo, K. (2002). A fluorescent Tie1 reporter allows monitoring of vascular development and endothelial cell isolation from transgenic mouse embryos. FASEB J. 16, 1764-1774. (Pubitemid 35340357)
16. Kaipainen, A., Korhonen, J., Mustonen, T., van Hinsbergh, V. W., Fang, G. H., Dumont, D., Breitman, M. and Alitalo, K. (1995). Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc. Natl. Acad. Sci. USA 92, 3566-3570.
17. Kim, K. L., Shin, I. S., Kim, J. M., Choi, J. H., Byun, J., Jeon, E. S., Suh, W. and Kim, D. K. (2006). Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells. Cardiovasc. Res. 72, 394-402. (Pubitemid 44665844)
18. Kontos, C. D., Cha, E. H., York, J. D. and Peters, K. G. (2002). The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis. Mol. Cell. Biol. 22, 1704-1713.
19. Korhonen, J., Polvi, A., Partanen, J. and Alitalo, K. (1994). The mouse tie receptor tyrosine kinase gene: expression during embryonic angiogenesis. Oncogene 9, 395-403. (Pubitemid 24041518)
20. Korhonen, J., Lahtinen, I., Halmekyto, M., Alhonen, L., Janne, J., Dumont, D. and Alitalo, K. (1995). Endothelial-specific gene expression directed by the tie gene promoter in vivo. Blood 86, 1828-1835.
21. Kuhnert, F., Campagnolo, L., Xiong, J. W., Lemons, D., Fitch, M. J., Zou, Z., Kiosses, W. B., Gardner, H. and Stuhlmann, H. (2005). Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev. Biol. 283, 140-156. (Pubitemid 40828847)
22. Lakso, M., Pichel, J. G., Gorman, J. R., Sauer, B., Okamoto, Y., Lee, E., Alt, F. W. and Westphal, H. (1996). Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl. Acad. Sci. USA 93, 5860-5865. (Pubitemid 26190768)
23. Makinen, T., Adams, R. H., Bailey, J., Lu, Q., Ziemiecki, A., Alitalo, K., Klein, R. and Wilkinson, G. A. (2005). PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev. 19, 397-410. (Pubitemid 40189302)
24. Marron, M. B., Hughes, D. P., Edge, M. D., Forder, C. L. and Brindle, N. P. (2000). Evidence for heterotypic interaction between the receptor tyrosine kinases Tie-1 and Tie-2. J. Biol. Chem. 275, 39741-39746.
25. McCarthy, M. J., Burrows, R., Bell, S. C., Christie, G., Bell, P. R. F. and Brindle, N. P. (1999). Potential roles of metalloprotease mediated ectodomain cleavage in signaling by the endothelial receptor tyrosine kinase Tie-1. Lab. Invest. 79, 889-895. (Pubitemid 29344501)
26. Morisada, T., Oike, Y., Yamada, Y., Urano, T., Akao, M., Kubota, Y., Maekawa, H., Kimura, Y., Ohmura, M., Miyamoto, T. et al. (2005). Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation. Blood 105, 4649-4656. (Pubitemid 40807284)
27. Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W. and Roder, J. C. (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428. (Pubitemid 23277681)
28. Oliver, G. (2004). Lymphatic vasculature development. Nat. Rev. Immunol. 4, 35-45.
29. Oliver, G. and Detmar, M. (2002). The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev. 16, 773-783. (Pubitemid 34280101)
30. Oliver, G. and Alitalo, K. (2005). The lymphatic vasculature: recent progress and paradigms. Annu. Rev. Cell Biol. 21, 457-483. (Pubitemid 41740643)
31. Oliver, G. and Srinivasan, R. S. (2008). Lymphatic vasculature development: current concepts. Ann. New York Acad. Sci. 1131, 75-81. (Pubitemid 351758504)
32. Partanen, J., Armstrong, E., Makela, T. P., Korhonen, J., Sandberg, M., Renkonen, R., Knuutila, S., Huebner, K. and Alitalo, K. (1992). A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains. Mol. Cell. Biol. 12, 1698-1707.
33. Peters, K. G., Kontos, C. D., Lin, P. C., Wong, A. L., Rao, P., Huang, L., Dewhirst, M. W. and Sankar, S. (2004). Functional significance of Tie2 signaling in the adult vasculature. Recent Prog. Horm. Res. 59, 51-71.
34. Petrova, T. V., Karpanen, T., Norrmen, C., Mellor, R., Tamakoshi, T., Finegold, D., Ferrell, R., Kerjaschki, D., Mortimer, P., Yla-Herttuala, S. et al. (2004). Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. Nat. Med. 10, 974-981. (Pubitemid 39273739)
35. Puri, M. C., Rossant, J., Alitalo, K., Bernstein, A. and Partanen, J. (1995). The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J. 14, 5884-5891.
36. Puri, M. C., Partanen, J., Rossant, J. and Bernstein, A. (1999). Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development. Development 126, 4569-4580. (Pubitemid 28554863)
37. Sabin, F. R. (1909). The lymphatic system in human embryos, with a consideration of the morphology of the system as a whole. Am. J. Anat. 9, 43-91.
38. Saharinen, P., Kerkelä, K., Ekman, N., Marron, M., Brindle, N., Lee, G. M., Augustin, H., Koh, G. Y. and Alitalo, K. (2005). Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2. J. Cell Biol. 169, 239-243. (Pubitemid 40656562)
39. Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg-Buchholz, K., Fujiwara, Y., Gendron-Maguire, M., Gridley, T., Wolburg, H., Risau, W. and Qin, Y. (1995). Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376, 70-74.
40. Schacht, V., Ramirez, M. I., Hong, Y. K., Hirakawa, S., Feng, D., Harvey, N., Williams, M., Dvorak, A. M., Dvorak, H. F., Oliver, G. et al. (2003). T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J. 22, 3546-3556. (Pubitemid 36898332)
41. Singh, H., Milner, C. S., Aguilar Hernandez, M. M., Patel, N. and Brindle, N. P. (2009). Vascular endothelial growth factor activates the Tie family of receptor tyrosine kinases. Cell. Signal. 21, 1346-1350.
42. Srinivasan, R. S., Dillard, M. E., Lagutin, O. V., Lin, F. J., Tsai, S., Tsai, M. J., Samokhvalov, I. M. and Oliver, G. (2007). Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 21, 2422-2432. (Pubitemid 47529372)
43. Taichman, D. B., Schachtner, S. K., Li, Y., Puri, M. C., Bernstein, A. and Baldwin, H. S. (2003). A unique pattern of Tie1 expression in the developing murine lung. Exp. Lung Res. 29, 113-122. (Pubitemid 36269793)
44. Tammela, T., Saaristo, A., Lohela, M., Morisada, T., Tornberg, J., Norrmen, C., Oike, Y., Pajusola, K., Thurston, G., Suda, T. et al. (2005). Angiopoietin-1 promotes lymphatic sprouting and hyperplasia. Blood 105, 4642-4648. (Pubitemid 40807283)
45. Wigle, J. T. and Oliver, G. (1999). Prox1 function is required for the development of the murine lymphatic system. Cell 98, 769-778.
46. Yabkowitz, R., Meyer, S., Black, T., Elliott, G., Merewether, L. A. and Yamane, H. K. (1999). Inflammatory cytokines and vascular endothelial growth factor stimulate the release of soluble Tie receptor from human endothelial cells via metalloprotease activation. Blood 93, 1969-1979. (Pubitemid 29128499)
47. Yancopoulos, G. D., Davis, S., Gale, N. W., Rudge, J. S., Wiegand, S. J. and Holash, J. (2000). Vascular-specific growth factors and blood vessel formation. Nature 407, 242-248.
48. Yano, M., Iwama, A., Nishio, H., Suda, J., Takada, G. and Suda, T. (1997). Expression and function of murine receptor tyrosine kinases, TIE and TEK, in hematopoietic stem cells. Blood 89, 4317-4326. (Pubitemid 27260239)
49. Yuan, H. T., Venkatesha, S., Chan, B., Deutsch, U., Mammoto, T., Sukhatme, V. P., Woolf, A. S. and Karumanchi, S. A. (2007). Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival. FASEB J. 21, 3171-3183. (Pubitemid 47565536)
50. Yuan, L., Moyon, D., Pardanaud, L., Breant, C., Karkkainen, M. J., Alitalo, K. and Eichmann, A. (2002). Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development 129, 4797-4806. (Pubitemid 35282411)