Biochemical study of a new inhibitor-resistant β-lactamase, SHV-84, produced by a clinical Escherichia coli strain

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 5, 2010, Pages 2271-2272

  Manageiro, Vera ^a   Ferreira, Eugénia ^a   Albuquerque, Luís ^b   Bonnet, Richard ^c   Caniça, Manuela ^a  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; BETA LACTAMASE; BETA LACTAMASE SHV; BETA LACTAMASE SHV 1; BETA LACTAMASE SHV 56; BETA LACTAMASE SHV 72; BETA LACTAMASE SHV 84; CEFALOTIN; CEPHALOSPORIN DERIVATIVE; PENICILLIN G; PIPERACILLIN PLUS TAZOBACTAM; PLASMID VECTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBIOTIC SENSITIVITY; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATION; BINDING AFFINITY; BIOCHEMISTRY; CATALYSIS; ENZYME ACTIVITY; ENZYME PURIFICATION; ESCHERICHIA COLI; EXTRACTION; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; HUMAN; IC 50; ISOELECTRIC POINT; LETTER; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL;

BETA-LACTAM RESISTANCE; BETA-LACTAMASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MOLECULAR SEQUENCE DATA;

EID: 77951228467     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01442-09     Document Type: Letter

References (9)

1. Caniça, M. M., M. Barthelemy, L. Gilly, R. Labia, R. Krishnamoorthy, and G. Paul. 1997. Properties of IRT-14 (TEM-45), a newly characterized mutant of TEM-type β-lactamases. Antimicrob. Agents Chemother. 41:374-378.
2. Cavallo, J. D., H. Chardon, C. Chidiac, P. Courvalin, H. Dabernat, H. Drugeon, L. Dubreuil, B. Guery, V. Jarlier, T. Lambert, R. Leclercq, M. H. Nicolas-Chanoine, C. Quentin, B. Rouveix, C. J. Soussy, and E. Varon. 2009. Recommandations 2009. Comité de l'antibiogramme de la Societé Française de Microbiologie, Paris, France.
3. Chang, F.-Y., L. K. Siu, C.-P. Fung, M.-H. Huang, and M. Ho. 2001. Diversity of SHV and TEM β-lactamase in Klebsiella pneumoniae: gene evolution in northern Taiwan and two novel β-lactamases, SHV-25 and SHV-26. Antimicrob. Agents Chemother. 45:2407-2413.
4. Dubois, V., L. Poirel, C. Arpin, L. Coulange, C. Bebear, P. Nordmann, and C. Quentin. 2004. SHV-49, a novel inhibitor-resistant β-lactamase in a clinical isolate of Klebsiella pneumoniae. Antimicrob. Agents Chemother. 48:4466-4469.
5. Dubois, V., L. Poirel, F. Demarthe, C. Arpin, L. Coulange, L. A. R. Minarini, M. Bezian, P. Nordmann, and C. Quentin. 2008. Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant β-lactamase from Klebsiella pneumoniae. Antimicrob. Agents Chemother. 52:3792-3794.
6. Labia, R., J. Andrillon, and F. Le Goffic. 1973. Computerized microacidimetric determination of β-lactamase Michaelis-Menten constants. FEBS Lett. 33:42-44.
7. Mendonça, N., J. Leitão, V. Manageiro, E. Ferreira, the Antimicrobial Resistance Surveillance Program in Portugal, and M. Caniça. 2007. Spread of extended-spectrum beta-lactamase CTX-M-producing Escherichia coli clinical isolates in community and nosocomial environments in Portugal. Antimicrob. Agents Chemother. 51:1946-1955.
8. Mendonça, N., V. Manageiro, F. Robin, M. J. Salgado, E. Ferreira, M. Caniça, and R. Bonnet. 2008. The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. Antimicrob. Agents Chemother. 52:1806-1811.
9. Prinarakis, E. E., V. Miriagou, E. Tzelepi, M. Gazouli, and L. S. Tzouvelekis. 1997. Emergence of an inhibitor-resistant β-lactamase (SHV-10) derived from an SHV-5 variant. Antimicrob. Agents Chemother. 41:838-840.