-
1
-
-
33644956702
-
TNFalpha- And IKKbeta-mediated TANK/I-TRAF phosphorylation: Implications for interaction with NEMO/IKKgamma and NF-kappaB activation
-
Bonif M,Meuwis MA, Close P, Benoit V, Heyninck K, Chapelle JP, Bours V, Merville MP, Piette J, Beyaert R, Chariot A. 2006. TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: Implications for interaction with NEMO/IKKgamma and NF-kappaB activation. Biochem J 394:593-603.
-
(2006)
Biochem J
, vol.394
, pp. 593-603
-
-
Bonif, M.1
Meuwis, M.A.2
Close, P.3
Benoit, V.4
Heyninck, K.5
Chapelle, J.P.6
Bours, V.7
Merville, M.P.8
Piette, J.9
Beyaert, R.10
Chariot, A.11
-
2
-
-
0035816547
-
Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma
-
Carter RS, Geyer BC, Xie M, cevedo-Suarez CA, Ballard DW. 2001. Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma. J Biol Chem 276:24445-24448.
-
(2001)
J Biol Chem
, vol.276
, pp. 24445-24448
-
-
Carter, R.S.1
Geyer, B.C.2
Xie, M.3
Cevedo-Suarez, C.A.4
Ballard, D.W.5
-
3
-
-
0037020147
-
Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases
-
Chariot A, Leonardi A, Muller J, Bonif M, Brown K, Siebenlist U. 2002. Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases. J Biol Chem 277:37029-37036.
-
(2002)
J Biol Chem
, vol.277
, pp. 37029-37036
-
-
Chariot, A.1
Leonardi, A.2
Muller, J.3
Bonif, M.4
Brown, K.5
Siebenlist, U.6
-
4
-
-
0036187476
-
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
-
DOI 10.1016/S1097-2765(02)00450-1
-
Chen G, Cao P, Goeddel DV. 2002. TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. Mol Cell 9:401-410. (Pubitemid 34195564)
-
(2002)
Molecular Cell
, vol.9
, Issue.2
, pp. 401-410
-
-
Chen, G.1
Cao, P.2
Goeddel, D.V.3
-
5
-
-
0035887525
-
Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1β-stimulated nuclear factor κB (NF-κB)pathway activation: IRAK-1 associates with the NF-κB essential modulator (NEMO) upon receptor stimulation
-
DOI 10.1042/0264-6021:3590403
-
Cooke EL, Uings IJ, Xia CL, Woo P, Ray KP. 2001. Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1 beta-stimulated nuclear factor kappa B (NF-kappa B) pathway activation: IRAK-1 associates with the NF-kappa B essential modulator (NEMO) upon receptor stimulation. Biochem J 359:403-410. (Pubitemid 32999786)
-
(2001)
Biochemical Journal
, vol.359
, Issue.2
, pp. 403-410
-
-
Cooke, E.-L.1
Uings, I.J.2
Xia, C.L.3
Woo, P.4
Ray, K.P.5
-
6
-
-
0141502126
-
KSHV vFLIP binds to IKK-γ to activate IKK
-
DOI 10.1242/jcs.00691
-
Field N, Low W, Daniels M, Howell S, Daviet L, Boshoff C, Collins M. 2003. KSHV v FLIP binds to IKK-gamma to activate IKK. J Cell Sci 116:3721-3728. (Pubitemid 37185301)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.18
, pp. 3721-3728
-
-
Field, N.1
Low, W.2
Daniels, M.3
Howell, S.4
Daviet, L.5
Boshoff, C.6
Collins, M.7
-
7
-
-
0033551607
-
IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus tax protein
-
DOI 10.1074/jbc.274.33.22911
-
Harhaj EW, Sun SC. 1999. IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. J Biol Chem 274:22911-22914. (Pubitemid 129529114) (Pubitemid 29388031)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.33
, pp. 22911-22914
-
-
Harhaj, E.W.1
Sun, S.-C.2
-
8
-
-
33847191686
-
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling
-
Henn IH, Bouman L, Schlehe JS, Schlierf A, Schramm JE, Wegener E, Nakaso K, Culmsee C, Berninger B, Krappmann D, Tatzelt J, Winklhofer KF. 2007. Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling. J Neurosci 27:1868-1878.
-
(2007)
J Neurosci
, vol.27
, pp. 1868-1878
-
-
Henn, I.H.1
Bouman, L.2
Schlehe, J.S.3
Schlierf, A.4
Schramm, J.E.5
Wegener, E.6
Nakaso, K.7
Culmsee, C.8
Berninger, B.9
Krappmann, D.10
Tatzelt, J.11
Winklhofer, K.F.12
-
9
-
-
0344305376
-
Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress
-
DOI 10.1016/S0092-8674(03)00895-X
-
Huang TT, Wuerzberger-Davis SM, Wu ZH, Miyamoto S. 2003. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 115:565-576. (Pubitemid 37506045)
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 565-576
-
-
Huang, T.T.1
Wuerzberger-Davis, S.M.2
Wu, Z.-H.3
Miyamoto, S.4
-
10
-
-
28944447430
-
PIDD Mediates NF-κB activation in response to DNA damage
-
DOI 10.1016/j.cell.2005.09.036, PII S0092867405010421
-
Janssens S, Tinel A, Lippens S, Tschopp J. 2005. PIDD mediates NF-kappaB activation in response to DNA damage. Cell 123:1079-1092. (Pubitemid 41785422)
-
(2005)
Cell
, vol.123
, Issue.6
, pp. 1079-1092
-
-
Janssens, S.1
Tinel, A.2
Lippens, S.3
Tschopp, J.4
-
11
-
-
0037134478
-
The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the IκB kinase complex
-
DOI 10.1074/jbc.M110480200
-
Liu L, Eby MT, Rathore N, Sinha SK, Kumar A, Chaudhary PM. 2002. The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex. J Biol Chem 277:13745-13751. (Pubitemid 34967977)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 13745-13751
-
-
Liu, L.1
Eby, M.T.2
Rathore, N.3
Sinha, S.K.4
Kumar, A.5
Chaudhary, P.M.6
-
12
-
-
33748188499
-
PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress
-
DOI 10.1038/ncb1458, PII NCB1458
-
Mabb AM, Wuerzberger-Davis SM, Miyamoto S. 2006. PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress. Nat Cell Biol 8:986-993. (Pubitemid 44314730)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.9
, pp. 986-993
-
-
Mabb, A.M.1
Wuerzberger-Davis, S.M.2
Miyamoto, S.3
-
13
-
-
33744904714
-
The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-κB pathway
-
DOI 10.1002/jcp.20644
-
Miranda C, Roccato E, Raho G, Pagliardini S, Pierotti MA, Greco A. 2006. The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway. J Cell Physiol 208:154-160. (Pubitemid 43849000)
-
(2006)
Journal of Cellular Physiology
, vol.208
, Issue.1
, pp. 154-160
-
-
Miranda, C.1
Roccato, E.2
Raho, G.3
Pagliardini, S.4
Pierotti, M.A.5
Greco, A.6
-
14
-
-
33845606399
-
Sustained activation of protein kinase C downregulates nuclear factorkappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells
-
Park KA, Byun HS, Won M, Yang KJ, Shin S, Piao L, Kim JM, Yoon WH, Junn E, Park J, Seok JH, Hur GM. 2007. Sustained activation of protein kinase C downregulates nuclear factorkappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells. Carcinogenesis 28:71-80.
-
(2007)
Carcinogenesis
, vol.28
, pp. 71-80
-
-
Park, K.A.1
Byun, H.S.2
Won, M.3
Yang, K.J.4
Shin, S.5
Piao, L.6
Kim, J.M.7
Yoon, W.H.8
Junn, E.9
Park, J.10
Seok, J.H.11
Hur, G.M.12
-
15
-
-
0035793582
-
VCLAP, a Caspase-recruitment Domain-containing Protein of Equine Herpesvirus-2, Persistently Activates the IκB Kinases through Oligomerization of IKKγ
-
DOI 10.1074/jbc.C000792200
-
Poyet JL, Srinivasula SM, Alnemri ES. 2001. v CLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma. J Biol Chem 276:3183-3187. (Pubitemid 37411610) (Pubitemid 33646730)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.5
, pp. 3183-3187
-
-
Poyet, J.-L.1
Srinivasula, S.M.2
Alnemri, E.S.3
-
16
-
-
0032541657
-
IKK-γ is an essential regulatory subunit of the IκB kinase complex
-
DOI 10.1038/26261
-
Rothwarf DM, Zandi E, Natoli G, Karin M. 1998. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 395:297-300. (Pubitemid 28447557)
-
(1998)
Nature
, vol.395
, Issue.6699
, pp. 297-300
-
-
Rothwarf, D.M.1
Zandi, E.2
Natoli, G.3
Karin, M.4
-
17
-
-
70449102637
-
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation
-
Stilmann M, Hinz M, Arslan SC, Zimmer A, Schreiber V, Scheidereit C. 2009. A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation. Mol Cell 36:365-378.
-
(2009)
Mol Cell
, vol.36
, pp. 365-378
-
-
Stilmann, M.1
Hinz, M.2
Arslan, S.C.3
Zimmer, A.4
Schreiber, V.5
Scheidereit, C.6
-
18
-
-
4544273345
-
Physical and functional interaction of CARMA1 and CARMA3 with iκ kinase γ-NFκB essential modulator
-
DOI 10.1074/jbc.M402244200
-
Stilo R, Liguoro D, Di JB, Formisano S, Consiglio E, Leonardi A, Vito P. 2004. Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator. J Biol Chem 279:34323-34331. (Pubitemid 39318056)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34323-34331
-
-
Stilo, R.1
Liguoro, D.2
Di Jeso, B.3
Formisano, S.4
Consiglio, E.5
Leonardi, A.6
Vito, P.7
-
19
-
-
0141621240
-
A role for NF-κB essential modifier/IκB kinase-γ (NEMO/IKKγ) ubiquitination in the activation of the IκB kinase complex by tumor necrosis factor-α
-
DOI 10.1074/jbc.M303389200
-
Tang ED, Wang CY, Xiong Y, Guan KL. 2003. A role for NF-kappaB essential modifier/ IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. J Biol Chem 278:37297-37305. (Pubitemid 37175246)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37297-37305
-
-
Tang, E.D.1
Wang, C.-Y.2
Xiong, Y.3
Guan, K.-L.4
-
20
-
-
40749139505
-
Interleukin-1 (IL-1) induces the Lys63- Linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase
-
Windheim M, Stafford M, Peggie M, Cohen P. 2008. Interleukin-1 (IL-1) induces the Lys63- linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase. Mol Cell Biol 28:1783-1791.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1783-1791
-
-
Windheim, M.1
Stafford, M.2
Peggie, M.3
Cohen, P.4
-
21
-
-
42949098959
-
NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
-
Wu CJ, Ashwell JD. 2008. NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Proc Natl Acad Sci USA 105:3023-3028.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3023-3028
-
-
Wu, C.J.1
Ashwell, J.D.2
-
22
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation
-
corrected
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD. 2006a. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol 8:398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
23
-
-
33644538632
-
Molecular linkage between the kinase ATM and NF-κB signaling in response to genotoxic stimuli
-
DOI 10.1126/science.1121513
-
Wu ZH, Shi Y, Tibbetts RS, Miyamoto S. 2006b. Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli. Science 311:1141-1146. (Pubitemid 43305951) (Pubitemid 43305951)
-
(2006)
Science
, vol.311
, Issue.5764
, pp. 1141-1146
-
-
Wu, Z.-H.1
Shi, Y.2
Tibbetts, R.S.3
Miyamoto, S.4
-
24
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
-
Yamaoka S, Courtois G, Bessia C, Whiteside ST, Weil R, Agou F, Kirk HE, Kay RJ, Israel A. 1998. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93:1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
Whiteside, S.T.4
Weil, R.5
Agou, F.6
Kirk, H.E.7
Kay, R.J.8
Israel, A.9
-
25
-
-
0033712615
-
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation
-
Zhang SQ, Kovalenko A, Cantarella G, Wallach D. 2000. Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation. Immunity 12:301-311.
-
(2000)
Immunity
, vol.12
, pp. 301-311
-
-
Zhang, S.Q.1
Kovalenko, A.2
Cantarella, G.3
Wallach, D.4
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