Mutation of actin tyr-53 alters the conformations of the DNase I-binding loop and the nucleotide-binding cleft

Journal of Biological Chemistry

Volumn 285, Issue 13, 2010, Pages 9729-9739

  Liu, Xiong ^a   Shu, Shi ^a   Hong, Myoung Soon S ^a   Yu, Bin ^a   Korn, Edward D ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING CLEFTS; BINDING LOOP; BIOCHEMICAL PROPERTIES; CELL PHENOTYPE; CRITICAL CONCENTRATION; DICTYOSTELIUM; DYNAMIC MODIFICATIONS; F-ACTIN; FUNCTIONAL CONFORMATIONS; GLU MUTATIONS; LOOP CONFORMATION; NUCLEOTIDE EXCHANGE;

CONFORMATIONS; FILAMENTS (LAMP); FUNCTIONAL POLYMERS; NUCLEOTIDES; OLIGOMERS; PHOSPHORYLATION; POLYMERIZATION; POLYMERS; PURIFICATION;

PROTEINS;

ACTIN; ALANINE; DEOXYRIBONUCLEASE I; GLUTAMIC ACID; LEUCINE; NUCLEOTIDE; PHENYLALANINE; TRYPTOPHAN; TYROSINE; COMPLEMENTARY DNA; MYOSIN II; SUBTILISIN;

ACTIN FILAMENT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME STRUCTURE; GROWTH INHIBITION; MUTATION; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; ANIMAL; CHEMISTRY; DICTYOSTELIUM; GENETICS; METABOLISM; PHENOTYPE; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

DICTYOSTELIUM;

ACTINS; ANIMALS; DEOXYRIBONUCLEASE I; DICTYOSTELIUM; DNA, COMPLEMENTARY; MUTATION; MYOSIN TYPE II; NUCLEOTIDES; PHENOTYPE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBTILISIN; TYROSINE;

EID: 77951219690     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.073452     Document Type: Article

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