Effect of β3-adrenergic agonists on alveolar fluid clearance in hypoxic rat lungs

Chinese Medical Journal

Volumn 123, Issue 8, 2010, Pages 1028-1033

  Li, Nai Jing ^a   Li, Wei ^b   He, Ping ^a   Gu, Xiu ^a   Li, Sheng Qi ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

3 adrenergic agonists; Alveolar fluid clearance; Hypoxia; Pulmonary edema

Indexed keywords

1 (2 ETHYLPHENOXY) 3 (1,2,3,4 TETRAHYDRO 1 NAPHTHYLAMINO) 2 PROPANOL OXALATE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; AMILORIDE; ATENOLOL; COLCHICINE; LUMICOLCHICINE; OUABAIN; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ETHANOLAMINE DERIVATIVE; PROPANOLAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIUM; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; DRUG INHIBITION; HEMOSTASIS; HYPEREMIA; HYPOXIA; LAMELLAR BODY; LUNG ALVEOLUS EPITHELIUM; LUNG BLOOD VESSEL; LUNG CLEARANCE; LUNG DEAD SPACE; LUNG EDEMA; LUNG FLUID; LUNG INJURY; MALE; MICROVILLUS; MITOCHONDRION; NONHUMAN; OXYGENATION; PETECHIA; RAT; TOTAL LUNG CAPACITY; ANIMAL; ANOXIA; BODY FLUID; DRUG EFFECT; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

ADRENERGIC BETA-AGONISTS; ANIMALS; ANOXIA; BODY FLUIDS; ETHANOLAMINES; MALE; PROPANOLAMINES; PULMONARY ALVEOLI; PULMONARY EDEMA; RATS; RATS, WISTAR;

EID: 77951219058     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.08.010     Document Type: Article

References (26)

1. Gu X, Wang Z, Xu J, Maeda S, Sugita M, Sagawa M, et al. Denopamine stimulates alveolar fluid clearance via cystic fibrosis transmembrane conductance regulator in rat lungs. Respirology 2006; 11: 566-571.
2. Zhou B, Zhou HY, Xu PH, Wang HM, Lin XM, Wang XD. Hyperoxygenated solution for improved oxygen supply in patients undergoing lung lavage for pulmonary alveolar proteinosis. Chin Med J 2009; 122: 1780-1783.
3. Hastings RH, Folkesson HG, Matthay MA. Mechanisms of alveolar protein clearance in the intact lung. Am J Physiol Lung Cell Mol Physiol 2003; 286: L679-L689.
4. Mehta D, Bhattacharya J, Matthay MA, Malik AB. Integrated control of lung fluid balance. Am J Physiol Lung Cell Mol Physiol 2004; 287: L1081-L1090.
5. Cheng IW, Ware LB, Greene KE, Nuckton TJ, Eisner MD, Matthay MA. Prognostic value of surfactant proteins A and D in patients with acute lung injury. Crit Care Med 2003; 31: 20-27.
6. Sartori C, Matthay MA. Alveolar epithelial fluid transport in acute lung injury: new insights. Eur Respir J 2002; 20: 1299-1313.
7. Gauthier C, Tavernier G, Trochu JN, Leblais V, Laurent K, Langin D, et al. Interspecies differences in the cardiac negative inotropic effects of β3-adrenoceptor agonists. Pharmacology 1999; 290: 687-693.
8. Gu X, Li SQ, Sakuma T. Effects of β-adrenergic agonists on alveolar fluid clearance in rat lungs. Chin J Tuberc Respir Dis (Chin) 2005; 28: 390-393.
9. Feng XW, Kang J, Wang ZF, Wang W, Yu RJ. The effect of chronic intermittent hypoxia to hypothalamus pituitary-adrenal axis and growth hormone level in rats during sleep. Chin J Appl Physiol (Chin) 2005; 21: 414-417.
10. Sakuma T, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, et al. Effects of hypoxia on alveolar fluid transport capacity in rat lungs. J Appl Physiol 2001; 91: 1766-1774.
11. Noble WH, Obdrzalek J, Kay JC. A new technique for measuring pulmonary edema. J Appl Physiol 1973; 34: 508-512.
12. Saldias FJ, Comellas AP, Pesce L, Lecuona E, Sznzjder JI. Dopamine increases lung liquid clearance during mechanical ventilation. Am J Respir Crit Care Me 2002; 22: L136-L143.
13. +channels in alveolar epithelial cells. Am J Physiol 1996; 271: L1-L22.
14. Borok Z, Verkman AS. Lung edema clearance: 20 years of progress: invited review: role of aquqporin water channels in fluid transport in lung and airways. J Appl Physiol 2002; 93: 2199-2206.
15. Berthiaume Y, Folkesson HG., Matthay MA. Lung edema clearance: 20 years of progress: invited review: alveolar fluid clearance in the injured lung. J Appl Physiol 2002; 93: 2207-2213.
16. Marie LV, Michael M, Marcel BC. Hypoxia reduces alveolar epithelial sodium and fluid transport in rats. Am J Respir Cell Mol Biol 2001; 25: 554-561.
17. Groshaus HE, Manocha S, Walley KR. Mechanisms of beta-receptor stimulation-induced improvement of acute lung injury and pulmonary edema. Crit Care 2004; 8: 234-242.
18. Perkins GD, Mcauley DF, Richter A. Bench-to-bedside review: beta2-agonists and the acute respiratory distress syndrome. Crit Care 2004; 8: 25-32.
19. Matthay MA, Fukuda N, Frank J, Kallet B. Alveolar epithelial barrier: role in lung fluid balance in clinical lung injury. Clin Chest Med 2000; 21: 477-490.
20. Kim H, Pennisi PA, Gavrilova O, Pack S, Jou W, Portas JS. Effect of adipocyte beta3-adrenergic receptor activation on the type 2 diabetic MKR mice. Am J Physiol Endocrinol Metab 2006; 290: 1227-1236.
21. Dada LA, Sznajder JI. Mechanisms of pulmonary edema clearance during acute hypoxemic respiratory failure: role of the Na, K-ATPase. Cri Care Med 2003; 31 (4 Suppl): S248-S252.
22. Matthay MA, Robriquet L, Fang X. Alveolar epithelium: role in lung fluid balance and acute lung injury. Proc Am Thorac Soc 2005; 2: 206-213.
23. Garat C, Carter EP, Matthay MA. New in situ mouse model to quantify alveolar epithelial fluid clearance. J Appl Physiol 1998; 84: 1763-1767.
24. Saldias FJ, Comellas A, Guerrero C, Ridge KM, Rutschman DH, Sznajder JI. Time course of active and passive liquid and solute movement in the isolated perfused rat lung model. J Appl Physiol 1998; 85: 1572-1577.
25. Sakuma T, Okaniwa T, Nakada T, Nishimura T, Fujimura S, Matthay MA. Alveolar fluid clearance in the resected human lung. Am J Respir Crit Care Med 1994; 150: 305-310.
26. Fukuda N, Folkesson HG, Matthay MA. Relationship of interstitial fluid volume to alveolar fluid clearance in mice: ventilated vs. in situ studies. J Appl Physiol 2000; 89: 672-679.