Pharmacokinetics of clindamycin in pregnant women in the peripartum period

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 5, 2010, Pages 2175-2181

  Muller, Anouk E ^a   Mouton, Johan W ^b,f   Oostvogel, Paul M ^a   Dörr, P Joep ^a   Voskuyl, Rob A ^c   DeJongh, Joost ^c,d   Steegers, Eric A P ^e   Danhof, Meindert ^c,d  

^a MEDICAL CENTER HAAGLANDEN   (Netherlands)

^b CANISIUS WILHELMINA HOSPITAL   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d LAP and P Consultants BV   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CLINDAMYCIN;

ADULT; ARTERIAL BLOOD; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG CLEARANCE; DRUG DISTRIBUTION; ENDOCARDITIS; FEMALE; GROUP B STREPTOCOCCAL INFECTION; HUMAN; MATERNAL BLOOD; MATERNAL SERUM; MINIMUM INHIBITORY CONCENTRATION; MONTE CARLO METHOD; PERINATAL CARE; PREGNANT WOMAN; PRIORITY JOURNAL; PROTEIN BINDING; STEADY STATE; UMBILICAL CORD BLOOD; UMBILICAL VEIN;

ADULT; ANTI-BACTERIAL AGENTS; CLINDAMYCIN; FEMALE; FETAL BLOOD; HUMANS; INFUSIONS, INTRAVENOUS; MODELS, BIOLOGICAL; MONTE CARLO METHOD; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS AGALACTIAE; UMBILICAL ARTERIES; UMBILICAL VEINS;

EID: 77951212204     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01017-09     Document Type: Article

References (34)

1. Ambrose, P. G., S. M. Bhavnani, C. M. Rubino, A. Louie, T. Gumbo, A. Forrest, and G. L. Drusano. 2007. Pharmacokinetics-pharmacodynamics of antimicrobial therapy: it's not just for mice anymore. Clin. Infect. Dis. 44: 79-86.
2. Ambrose, P. G., and D. M. Grasela. 2000. The use of Monte Carlo simulation to examine pharmacodynamic variance of drugs: fluoroquinolone pharmacodynamics against Streptococcus pneumoniae. Diagn. Microbiol. Infect. Dis. 38:151-157.
3. Beal, S. L., L. B. Sheiner, and A. J. Boeckmann. 1989-;-2006. NONMEM user's guides. Icon Development Solutions, Ellicott City, MD.
4. Bonate, P. L. 2005. Recommended reading in population pharmacokinetic pharmacodynamics. AAPS J. 7:E363-E373.
5. Craig, W. A., S. Kiem, and D. R. Andes. 2002. Free-drug AUC/MIC is the PK-PD target that correlates with in vivo efficacy of macrolides, azilides, ketolides and clindamycin, abstr. A-1264. Abstr. 42nd Intersci. Conf. Antimicrob. Agents Chemother. American Society for Microbiology, Washington, DC.
6. Drusano, G. L., D. Z. D'Argenio, S. L. Preston, C. Barone, W. Symonds, S. LaFon, M. Rogers, W. Prince, A. Bye, and J. A. Bilello. 2000. Use of drug effect interaction modeling with Monte Carlo simulation to examine the impact of dosing interval on the projected antiviral activity of the combination of abacavir and amprenavir. Antimicrob. Agents Chemother. 44:1655-1659.
7. Drusano, G. L., S. L. Preston, C. Hardalo, R. Hare, C. Banfield, D. Andes, O. Vesga, and W. A. Craig. 2001. Use of preclinical data for selection of a phase II/III dose for evernimicin and identification of a preclinical MIC breakpoint. Antimicrob. Agents Chemother. 45:13-22.
8. European Committee on Antimicrobial Susceptibility Testing. 2009. Antimicrobial wild type distributions of microorganisms. http://217.70.33.99/ Eucast2/. Accessed 1 July 2009.
9. Flaherty, J. F., Jr., G. Gatti, J. White, J. Bubp, M. Borin, and J. G. Gambertoglio. 1996. Protein binding of clindamycin in sera of patients with AIDS. Antimicrob. Agents Chemother. 40:1134-1138.
10. Flaherty, J. F., L. C. Rodondi, B. J. Guglielmo, J. C. Fleishaker, R. J. Townsend, and J. G. Gambertoglio. 1988. Comparative pharmacokinetics and serum inhibitory activity of clindamycin in different dosing regimens. Antimicrob. Agents Chemother. 32:1825-1829.
11. Gabrielsson, J., and D. Weimer. 2000. Pharmacokinetic concepts, p. 45-174. In Pharmacokinetic and pharmacodynamic data analysis: concepts & applications, 3rd ed. Apothekarsocieteten (Pharmaceutical Society), Stockholm, Sweden.
12. Gatti, G., J. Flaherty, J. Bubp, J. White, M. Borin, and J. Gambertoglio. 1993. Comparative study of bioavailabilities and pharmacokinetics of clindamycin in healthy volunteers and patients with AIDS. Antimicrob. Agents Chemother. 37:1137-1143.
13. Gordon, R. C., C. Regamey, and W. M. Kirby. 1973. Serum protein binding of erythromycin, lincomycin, and clindamycin. J. Pharm. Sci. 62:1074-1077.
14. Gygax, S. E., J. A. Schuyler, L. E. Kimmel, J. P. Trama, E. Mordechai, and M. E. Adelson. 2006. Erythromycin and clindamycin resistance in group B streptococcal clinical isolates. Antimicrob. Agents Chemother. 50:1875-1877.
15. Hall, C. M., D. W. Milligan, and J. Berrington. 2004. Probable adverse reaction to a pharmaceutical excipient. Arch. Dis. Child Fetal Neonatal Ed. 89:F184.
16. Kays, M. B., R. L. White, G. Gatti, and J. G. Gambertoglio. 1992. Ex vivo protein binding of clindamycin in sera with normal and elevated alpha 1-acid glycoprotein concentrations. Pharmacotherapy 12:50-55.
17. Kerr, J. R. 1994. Penicillin allergy: a study of incidence as reported by patients. Br. J. Clin. Pract. 48:5-7.
18. Kremer, J. M., J. Wilting, and L. H. Janssen. 1988. Drug binding to human alpha-1-acid glycoprotein in health and disease. Pharmacol. Rev. 40:1-47.
19. Matsubara, K., Y. Nishiyama, K. Katayama, G. Yamamoto, M. Sugiyama, T. Murai, and K. Baba. 2001. Change of antimicrobial susceptibility of group B streptococci over 15 years in Japan. J. Antimicrob. Chemother. 48:579-582.
20. Matteson, K. A., S. P. Lievense, B. Catanzaro, and M. G. Phipps. 2008. Intrapartum group B streptococci prophylaxis in patients reporting a penicillin allergy. Obstet. Gynecol. 111:356-364.
21. Menon, P. A., B. T. Thach, C. H. Smith, M. Landt, J. L. Roberts, R. E. Hillman, and L. S. Hillman. 1984. Benzyl alcohol toxicity in a neonatal intensive care unit. Incidence, symptomatology, and mortality. Am. J. Perinatol. 1:288-292.
22. Mouton, J. W. 2002. Breakpoints: current practice and future perspectives. Int. J. Antimicrob. Agents 19:323-331.
23. Mouton, J. W., N. Punt, and A. A. Vinks. 2005. A retrospective analysis using Monte Carlo simulation to evaluate recommended ceftazidime dosing regimens in healthy volunteers, patients with cystic fibrosis, and patients in the intensive care unit. Clin. Ther. 27:762-772.
24. Mouton, J. W., A. Schmitt-Hoffmann, S. Shapiro, N. Nashed, and N. C. Punt. 2004. Use of Monte Carlo simulations to select therapeutic doses and provisional breakpoints of BAL9141. Antimicrob. Agents Chemother. 48:1713-1718.
25. Muller, A. E., P. M. Oostvogel, J. DeJongh, J. W. Mouton, E. A. Steegers, P. J. Dorr, M. Danhof, and R. A. Voskuyl. 2009. Pharmacokinetics of amoxicillin in maternal, umbilical cord and neonatal sera. Antimicrob. Agents Chemother. 53:1574-1580.
26. Notarianni, L. J. 1990. Plasma protein binding of drugs in pregnancy and in neonates. Clin. Pharmacokinet. 18:20-36.
27. Philipson, A., L. D. Sabath, and D. Charles. 1973. Transplacental passage of erythromycin and clindamycin. N. Engl. J. Med. 288:1219-1221.
28. Plaisance, K. I., G. L. Drusano, A. Forrest, R. J. Townsend, and H. C. Standiford. 1989. Pharmacokinetic evaluation of two dosage regimens of clindamycin phosphate. Antimicrob. Agents Chemother. 33:618-620.
29. Schrag, S., R. Gorwitz, K. Fultz-Butts, and A. Schuchat. 2002. Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC. MMWR Recommend. Rep. 51(RR-11):1-22.
30. Sheiner, B. L., and S. L. Beal. 1981. Evaluation of methods for estimating population pharmacokinetic parameters. II. Biexponential model and experimental pharmacokinetic data. J. Pharmacokinet. Biopharm. 9:635-651.
31. Sheiner, B. L., and T. H. Grasela. 1991. An introduction to mixed effect modeling: concepts, definitions, and justification. J. Pharmacokinet. Biopharm. 19:11S-24S.
32. Suh, B., W. A. Craig, A. C. England, and R. L. Elliott. 1981. Effect of free fatty acids on protein binding of antimicrobial agents. J. Infect. Dis. 143: 609-616.
33. Townsend, R. J., and R. P. Baker. 1987. Pharmacokinetic comparison of three clindamycin phosphate dosing schedules. Drug Intell. Clin. Pharm. 21:279-281.
34. Weinstein, A. J., R. S. Gibbs, and M. Gallagher. 1976. Placental transfer of clindamycin and gentamicin in term pregnancy. Am. J. Obstet. Gynecol. 124:688-691.