Chronic in utero buprenorphine exposure causes prolonged respiratory effects in the guinea pig neonate

Neurotoxicology and Teratology

Volumn 32, Issue 3, 2010, Pages 398-405

  Wallisch, Michael ^a   Subban, Chinmayee V ^a   Nettleton, Rosemary T ^a   Olsen, George D ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Development; In utero buprenorphine; Neonatal abstinence syndrome; Opioids; Respiratory control; Substance abuse

Indexed keywords

BUPRENORPHINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; GUINEA PIG; LOCOMOTION; LONG TERM EXPOSURE; MALE; MORNING DOSAGE; NEWBORN; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RESPIRATORY FUNCTION; RESPIRATORY TRACT DISEASE; WITHDRAWAL SYNDROME;

ANIMALS; ANIMALS, NEWBORN; BUPRENORPHINE; CARBON DIOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GESTATIONAL AGE; GUINEA PIGS; MOTOR ACTIVITY; NARCOTIC ANTAGONISTS; OXYGEN CONSUMPTION; PLETHYSMOGRAPHY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RESPIRATION; RESPIRATORY FUNCTION TESTS; TOXICITY TESTS;

CAVIA;

EID: 77951207836     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ntt.2009.12.007     Document Type: Article

References (44)

1. Barrett D.A., Simpson J., Rutter N., Kurihara-Bergstrom T., Shaw P.N., Davis S.S. The pharmacokinetics and physiological effects of buprenorphine infusion in premature neonates. Br. J. Clin. Pharmacol. 1993, 36:215-219.
2. Belcheva M.M., Bohn L.M., Ho M.T., Johnson F.E., Yanai J., Barron S., Coscia C.J. Brain opioid receptor adaptation and expression after prenatal exposure to buprenorphine. Dev. Brain Res. 1998, 111:35-42.
3. Blake C.I., Banchero N. Ventilation and oxygen consumption in the guinea pig. Respir. Physiol 1985, 61:347-355.
4. Boothby L.A., Doering P.L. Buprenorphine for the treatment of opioid dependence. Am. J. Health Syst. Pharm. 2007, 64:266-272.
5. Cepeda M.S., Farrar J.T., Baumgarten M., Boston R., Carr D.B., Strom B.L. Side effects of opioids during short-term administration: effect of age, gender, and race. Clin. Pharmacol. Ther. 2003, 74:102-112.
6. Cichewicz D.L., Welch S.P., Smith F.L. Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol. Eur. J. Pharmacol. 2005, 525:74-82.
7. Collins G.B., McAllister M.S. Buprenorphine maintenance: a new treatment for opioid dependence. Clev. Clin. J. Med. 2007, 74:514-520.
8. Dahan A., Yassen A., Bijl H., Romberg R., Sarton E., Teppema L., Olofsen E., Danhof M. Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats. Br. J. Anaesth. 2005, 94:825-834.
9. Dahan A., Yassen A., Romberg R., Sarton E., Teppema L., Olofsen E., Danhof M. Buprenorphine induces ceiling in respiratory depression but not in analgesia. Br. J. Anaesth. 2006, 96:627-632.
10. Dawes G.S. The establishment of pulmonary respiration. Foetal And Neonatal Physiology: A comparative Study of the Changes at Birth 1968, 125-140. Year Book Medical Publishers, Inc, Chicago, IL. G.S. Dawes (Ed.).
11. Ebner N., Rohrmeister K., Winklbaur B., Baewert A., Jagsch R., Peternell A., Thau K., Fischer G. Management of neonatal abstinence syndrome in neonates born to opioid maintained women. Drug Alcohol Depend. 2007, 87:131-138.
12. Fischer G., Ortner R., Rohrmeister K., Jagsch R., Baewert A., Langer M., Aschauer H. Methadone versus buprenorphine in pregnant addicts: a double-blind, double-dummy comparison study. Addiction 2006, 101:275-281.
13. Hambrook J.M., Rance M.J. The interaction of buprenorphine with the opiate receptor: lipophilicity as a determining factor in drug-receptor kinetics. Opiates and Endogenous Opioid Peptides 1976, 295-301. Elsevier, Amsterdam. H.W. Kosterlitz (Ed.).
14. Hanson C.E., Ruble G.R., Essiet I., Hartman A.B. Effects of buprenorphine on immunogenicity and protective efficacy in the guinea pig keratoconjunctivitis model (Sereny test). Comp Med. 2001, 51:224-229.
15. Huestis M.A., Choo R.E. Drug abuse's smallest victims: in utero drug exposure. Forensic Sci. Int. 2002, 128:20-30.
16. Hunter M.A., Vangelisti G.R., Olsen G.D. Chronic intermittent in utero exposure to morphine: effects on respiratory control in the neonatal guinea pig. Biol. Neonate 1997, 72:293-304.
17. Jones H.E., Johnson R.E., Jasinski D.R., O'Grady K.E., Chisholm C.A., Choo R.E., Crocetti M., Dudas R., Harrow C., Huestis M.A., Jansson L.M., Lantz M., Lester B.M., Milio L. Buprenorphine versus methadone in the treatment of pregnant opioid-dependent patients: effects on the neonatal abstinence syndrome. Drug Alcohol Depend. 2005, 79:1-10.
18. Jones H.E., Martin P.R., Heil S.H., Kaltenbach K., Selby P., Coyle M.G., Stine S.M., O'Grady K.E., Arria A.M., Fischer G. Treatment of opioid-dependent pregnant women: clinical and research issues. J. Subst. Abuse Treat. 2008, 35:245-259.
19. Kahila H., Saisto T., Kivitie-Kallio S., Haukkamaa M., Halmesmaki E. A prospective study on buprenorphine use during pregnancy: effects on maternal and neonatal outcome. Acta Obstet. Gynecol. Scand. 2007, 86:185-190.
20. Kakko J., Heilig M., Sarman I. Buprenorphine and methadone treatment of opiate dependence during pregnancy: comparison of fetal growth and neonatal outcomes in two consecutive case series. Drug Alcohol Depend. 2008, 96:69-78.
21. Kaltenbach K., Berghella V., Finnegan L. Opioid dependence during pregnancy. Effects and management. Obstet. Gynecol. Clin. North Am. 1998, 25:139-151.
22. Kandall S.R., Gaines J. Maternal substance use and subsequent sudden infant death syndrome (SIDS) in offspring. Neurotoxicol. Teratol. 1991, 13:235-240.
23. Kandall S.R., Gaines J., Habel L., Davidson G., Jessop D. Relationship of maternal substance abuse to subsequent sudden infant death syndrome in offspring. J. Pediatr. 1993, 123:120-126.
24. Kleber H.D. Pharmacologic treatments for heroin and cocaine dependence. Am. J. Addict. 2003, 12(Suppl 2):S5-S18.
25. Lalley P.M. Opioidergic and dopaminergic modulation of respiration. Respir. Physiol Neurobiol. 2008, 164:160-167.
26. Lejeune C., Simmat-Durand L., Gourarier L., Aubisson S. Prospective multicenter observational study of 260 infants born to 259 opiate-dependent mothers on methadone or high-dose buprenorphine substitution. Drug Alcohol Depend. 2006, 82:250-257.
27. Lesser-Katz M. Some effects of maternal drug addiction on the neonate. Int. J. Addict. 1982, 17:887-896.
28. Matsuda A.Y., Olsen G.D. Chronic in utero morphine exposure alters mu-agonist-stimulated [35S]-GTPgammaS binding in neonatal and juvenile guinea pig brainstem regions associated with breathing control. Neurotoxicol. Teratol. 2001, 23:413-419.
29. Minozzi S., Amato L., Vecchi S., Davoli M. Maintenance agonist treatments for opiate dependent pregnant women. Cochrane. Database. Syst. Rev. 2008, 2:CD006318.
30. Murphey L.J., Olsen G.D. Morphine-6-beta-d-glucuronide respiratory pharmacodynamics in the neonatal guinea pig. J. Pharmacol. Exp. Ther. 1994, 268:110-116.
31. Nanovskaya T., Deshmukh S., Brooks M., Ahmed M.S. Transplacental transfer and metabolism of buprenorphine. J. Pharmacol. Exp. Ther. 2002, 300:26-33.
32. Nettleton R.T., Ransom T.A., Abraham S.L., Nelson C.S., Olsen G.D. Methadone-induced respiratory depression in the neonatal guinea pig. Pediatr. Pulmonol. 2007, 42:1134-1143.
33. Nettleton R.T., Wallisch M., Olsen G.D. Respiratory effects of chronic in utero methadone or morphine exposure in the neonatal guinea pig. Neurotoxicol. Teratol. 2008, 30:448-454.
34. Olsen G.D., Murphey L.J. Effects of morphine and cocaine on breathing control in neonatal animals: a minireview. NIDA Res. Monogr 1995, 158:22-39.
35. Olsen G.D., Weil J.A. In utero cocaine exposure: effect on neonatal breathing in guinea pigs. J. Pharmacol. Exp. Ther. 1992, 261:420-428.
36. Pritham U.A., Troese M., Stetson A. Methadone & buprenorphine treatment during pregnancy: what are the effects on infants?. Nurs. Womens Health 2007, 11:558-567.
37. Robinson S.E. Buprenorphine: an analgesic with an expanding role in the treatment of opioid addiction. CNS. Drug Rev. 2002, 8:377-390.
38. Robinson S.E., Wallace M.J. Effect of perinatal buprenorphine exposure on development in the rat. J. Pharmacol. Exp. Ther. 2001, 298:797-804.
39. Serane V.T., Kurian O. Neonatal abstinence syndrome. Indian J. Pediatr. 2008, 75:911-914.
40. Shook J.E., Watkins W.D., Camporesi E.M. Differential roles of opioid receptors in respiration, respiratory disease, and opiate-induced respiratory depression. Am. Rev. Respir. Dis. 1990, 142:895-909.
41. Stock C., Shum J.H. Buprenorphine:a new pharmacotherapy for opioid addictions treatment. J. Pain Palliat. Care Pharmacother. 2004, 18:35-54.
42. Tiong G.K., Olley J.E. Effects of exposure in utero to methadone and buprenorphine on enkephalin levels in the developing rat brain. Neurosci. Lett. 1988, 93:101-106.
43. Wang E.C. Methadone treatment during pregnancy. J. Obstet. Gynecol. Neonatal Nurs. 1999, 28:615-622.
44. Ziegler M., Poustka F., von Loewenich V., Englert E. Postpartum risk factors in the development of children born to opiate-addicted mothers; comparison between mothers with and without methadone substitution. Nervenarzt 2000, 71:730-736.