Stress failure and high-altitude pulmonary oedema: Mechanistic insights from physiology

European Respiratory Journal

Volumn 35, Issue 3, 2010, Pages 470-472

  Hopkins, S R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; NIFEDIPINE; SILDENAFIL; TADALAFIL;

ALTITUDE DISEASE; BLOOD GAS BARRIER; BLOOD VESSEL INJURY; EDITORIAL; HIGH ALTITUDE PULMONARY EDEMA; HUMAN; HYPOXIA; LUNG CAPILLARY; LUNG LAVAGE; PERMEABILITY BARRIER; PRIORITY JOURNAL; STRESS FAILURE;

ALTITUDE SICKNESS; ANIMALS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HUMANS; PULMONARY EDEMA; RATS;

EID: 77951176479     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00178709     Document Type: Editorial

References (35)

1. Schoene R, Swenson E, Hultgren H. High altitude pulmonary edema. In: Hornbein T, Schoene R, eds. High Altitude: An exploration of human adaptation. New York, Marcel Dekker Inc., 2001; pp. 777-814.
2. Cremona G, Asnaghi R, Baderna P, et al. Pulmonary extravascular fluid accumulation in recreational climbers: a prospective study. Lancet 2002; 359: 303-309. (Pubitemid 34119294)
3. West JB, Tsukimoto K, Mathieu-Costello O, et al. Stress failure in pulmonary capillaries. J Appl Physiol 1991; 70: 1731-1742.
4. West JB, Mathieu-Costello O. Stress failure of pulmonary capillaries: role in lung and heart disease. Lancet 1992; 340: 762-767.
5. Tsukimoto K, Mathieu-Costello O, Prediletto R, et al. Ultrastructural appearances of pulmonary capillaries at high transmural pressures. J Appl Physiol 1991; 71: 573-582.
6. Tsukimoto K, Yoshimura N, Ichioka M, et al. Protein, cell, and LTB4 concentrations of lung edema fluid produced by high capillary pressures in rabbit. J Appl Physiol 1994; 76: 321-327. (Pubitemid 24048262)
7. Hopkins SR, Schoene RB, Henderson WR, et al. Intense exercise impairs the integrity of the pulmonary blood-gas barrier in elite athletes. Am J Respir Crit Care Med 1997; 155: 1090-1094.
8. Schoene RB, Hackett PH, Henderson WR, et al. High-altitude pulmonary edema. Characteristics of lung lavage fluid. JAMA 1986; 256: 63-69.
9. Kubo K, Hanaoka M, Hayano T, et al. Inflammatory cytokines in BAL fluid and pulmonary hemodynamics in high-altitude pulmonary edema. Respir Physiol 1998; 111: 301-310. (Pubitemid 28243275)
10. Mairbaurl H, Schwobel F, Hoschele S, et al. Altered ion transporter expression in bronchial epithelium in mountaineers with high-altitude pulmonary edema. J Appl Physiol 2003; 95: 1843-1850. (Pubitemid 37310366)
11. Hultgren HN, Grover RF, Hartley LH. Abnormal circulatory responses to high altitude in subjects with a previous history of high-altitude pulmonary edema. Circulation 1971; 44: 759-770.
12. Kawashima A, Kubo K, Kobayashi T, et al. Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema. J Appl Physiol 1989; 67: 1982-1989. (Pubitemid 20039409)
13. Viswanathan R, Jain SK, Subramanian S, et al. Pulmonary edema of high altitude. II. Clinical, aerohemodynamic, and biochemical studies in a group with history of pulmonary edema of high altitude. Am Rev Respir Dis 1969; 100: 334-341.
14. Yagi H, Yamada H, Kobayashi T, et al. Doppler assessment of pulmonary hypertension induced by hypoxic breathing in subjects susceptible to high altitude pulmonary edema. Am Rev Respir Dis 1990; 142: 796-801. (Pubitemid 20344646)
15. Grunig E, Mereles D, Hildebrandt W, et al. Stress Doppler echocardiography for identification of susceptibility to high altitude pulmonary edema. J Am Coll Cardiol 2000; 35: 980-987. (Pubitemid 30189932)
16. Eldridge MW, Podolsky A, Richardson RS, et al. Pulmonary hemodynamic response to exercise in subjects with prior high-altitude pulmonary edema. J Appl Physiol 1996; 81: 911-921. (Pubitemid 26303248)
17. Oelz O, Maggiorini M, Ritter M, et al. Nifedipine for high altitude pulmonary oedema. Lancet 1989; 2: 1241-1244. (Pubitemid 19284124)
18. Scherrer U, Vollenweider L, Delabays A, et al. Inhaled nitric oxide for high-altitude pulmonary edema.N Engl J Med 1996; 334: 624-629.
19. Maggiorini M, Brunner-La Rocca HP, Peth S, et al. Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial. Ann Intern Med 2006; 145: 497-506. (Pubitemid 46780953)
20. Visscher MB. Studies on embolization of lung vessels. Med Thorac 1962; 19: 334-340.
21. Hultgren HN. Pulmonary hypertension and pulmonary edema. In: Loeppky JA, Riedesel ML, eds. Oxygen Transport to Human Tissue. New York, Elsevier/North Holland, 1982; pp. 243-254.
22. Hlastala MP, Lamm WJ, Karp A, et al. Spatial distribution of hypoxic pulmonary vasoconstriction in the supine pig. J Appl Physiol 2004; 96: 1589-1599. (Pubitemid 38579979)
23. Dehnert C, Risse F, Ley S, et al. Magnetic resonance imaging of uneven pulmonary perfusion in hypoxia in humans. Am J Respir Crit Care Med 2006; 174: 1132-1138. (Pubitemid 44772084)
24. Hopkins SR, Garg J, Bolar DS, et al. Pulmonary blood flow heterogeneity during hypoxia and high-altitude pulmonary edema. Am J Respir Crit Care Med 2005; 171: 83-87. (Pubitemid 40051700)
25. Swenson ER, Maggiorini M, Mongovin S, et al. Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor. JAMA 2002; 287: 2228-2235. (Pubitemid 34441939)
26. Bai C, She J, Goolaerts A, et al. Stress failure plays a major role in development of high-altitude pulmonary oedema in rats. Eur Respir J 2010; 35: 584-591.
27. West JB, Colice GL, Lee YJ, et al. Pathogenesis of high-altitude pulmonary oedema: direct evidence of stress failure of pulmonary capillaries. Eur Respir J 1995; 8: 523-529.
28. Whitwell KE, Greet TR. Collection and evaluation of tracheobronchial washes in the horse. Equine Vet J 1984; 16: 499-508.
29. McKechnie JK, Leary WP, Noakes TD, et al. Acute pulmonary oedema in two athletes during a 90-km running race. S Afr Med J 1979; 56: 261-265.
30. Weiler RD, Shupak A, Goldenberg I, et al. Pulmonary oedema and haemoptysis induced by strenuous swimming. BMJ 1995; 311: 361-362. (Pubitemid 30347469)
31. Amato MBP, Barbas CSV, Medeiros DM, et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998; 338: 347-354. (Pubitemid 28083906)
32. Fu Z, Costello ML, Tsukimoto K, et al. High lung volume increases stress failure in pulmonary capillaries. J Appl Physiol 1992; 73: 123-133.
33. West JB, Colice GL, Lee YJ, et al. Pathogenesis of high-altitude pulmonary oedema: direct evidence of stress failure of pulmonary capillaries. Eur Respir J 1995; 8: 523-529.
34. West JB, Mathieu-Costello O. Stress failure in pulmonary capillaries: a mechanism for high altitude pulmonary edema. In: Sutton JR, Coates G, Houston CS, eds. Hypoxia and Mountain Medicine. Burlington, Queen City Printers Inc., 1992; pp. 229-240.
35. Bernard, C, An Introduction to the Study of Experimental Medicine (1865). New York, Dover, 1927.