-
1
-
-
28144459814
-
High-dose acetylcysteine in idiopathic pulmonary fibrosis
-
DOI 10.1056/NEJMoa042976
-
Demedts M, Behr J, Buhl R, et al. High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med. 2005; 353: 2229-2242. (Pubitemid 41697286)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.21
, pp. 2229-2242
-
-
Demedts, M.1
Behr, J.2
Buhl, R.3
Costabel, U.4
Dekhuijzen, R.5
Jansen, H.M.6
MacNee, W.7
Thomeer, M.8
Wallaert, B.9
Laurent, F.10
Nicholson, A.G.11
Verbeken, E.K.12
Verschakelen, J.13
Flower, C.D.R.14
Capron, F.15
Petruzzelli, S.16
De Vuyst, P.17
Van Den Bosch, J.M.M.18
Rodriguez-Becerra, E.19
Corvasce, G.20
Lankhorst, I.21
Sardina, M.22
Montanari, M.23
more..
-
2
-
-
67650349068
-
Effect of interferon c-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebo-controlled trial
-
King TE Jr, Albera C, Bradford WZ, et al. Effect of interferon c-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial. Lancet 2009; 374: 222-228.
-
(2009)
Lancet
, vol.374
, pp. 222-228
-
-
King Jr., T.E.1
Albera, C.2
Bradford, W.Z.3
-
3
-
-
37849012578
-
BUILD-1: A randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr, Behr J, Brown KK, et al. BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008; 177: 75-81.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 75-81
-
-
King Jr., T.E.1
Behr, J.2
Brown, K.K.3
-
4
-
-
0345824715
-
A Placebo-Controlled Trial of Interferon Gamma-1b in Patients with Idiopathic Pulmonary Fibrosis
-
DOI 10.1056/NEJMoa030511
-
Raghu G, Brown KK, Bradford WZ, et al. A placebo-controlled trial of interferon c-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med 2004; 350: 125-133. (Pubitemid 38056223)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.2
, pp. 125-133
-
-
Raghu, G.1
Brown, K.K.2
Bradford, W.Z.3
Starko, K.4
Noble, P.W.5
Schwartz, D.A.6
King Jr., T.E.7
-
5
-
-
55549147184
-
Treatment of idiopathic pulmonary fibrosis with etanercept: An exploratory, placebo-controlled trial
-
Raghu G, Brown KK, Costabel U, et al. Treatment of idiopathic pulmonary fibrosis with etanercept: an exploratory, placebo-controlled trial. Am J Respir Crit Care Med 2008; 178: 948-955.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 948-955
-
-
Raghu, G.1
Brown, K.K.2
Costabel, U.3
-
6
-
-
77951160564
-
Pirfenidone in idiopathic pulmonary fibrosis
-
Taniguchi H, Ebina M, Kondoh Y, et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 2010; 35: 821-829.
-
(2010)
Eur Respir J
, vol.35
, pp. 821-829
-
-
Taniguchi, H.1
Ebina, M.2
Kondoh, Y.3
-
7
-
-
0032926937
-
Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: Results of a prospective, open-label phase II study
-
Raghu G, Johnson WC, Lockhart D, et al. Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label Phase II study. Am J Respir Crit Care Med 1999; 159: 1061-1069. (Pubitemid 29202536)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.159
, Issue.4
, pp. 1061-1069
-
-
Raghu, G.1
Johnson, W.C.2
Lockhart, D.3
Mageto, Y.4
-
8
-
-
0030694389
-
Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear statistical significance
-
DOI 10.1016/S0197-2456(97)00075-5, PII S0197245697000755
-
O'Neill RT. Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear statistical significance. Control Clin Trials 1997; 18: 550-556. (Pubitemid 27520843)
-
(1997)
Controlled Clinical Trials
, vol.18
, Issue.6
, pp. 550-556
-
-
O'Neill, R.T.1
-
9
-
-
0041874992
-
Changes in clinical and physiologic variables predict survival in idiopathic pulmonary fibrosis
-
Collard HR, King TE Jr, Bartelson BB, et al. Changes in clinical and physiologic variables predict survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2003; 168: 538-542.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 538-542
-
-
Collard, H.R.1
King Jr., T.E.2
Bartelson, B.B.3
-
10
-
-
13844316832
-
Analyses of efficacy end points in a controlled trial of interferon-c1b for idiopathic pulmonary fibrosis
-
DOI 10.1378/chest.127.1.171
-
King TE Jr, Safrin S, Starko KM, et al. Analyses of efficacy end points in a controlled trial of interferon-c-1b for idiopathic pulmonary fibrosis. Chest 2005; 127: 171-177. (Pubitemid 41724573)
-
(2005)
Chest
, vol.127
, Issue.1
, pp. 171-177
-
-
King Jr., T.E.1
Safrin, S.2
Starko, K.M.3
Brown, K.K.4
Noble, P.W.5
Raghu, G.6
Schwartz, D.A.7
-
11
-
-
34748860155
-
-
US Dept of Health and Human Services Food and Drug Administration, CBER, CDER, CDRH Available from: Date last accessed: December 29, 2009
-
US Dept of Health and Human Services Food and Drug Administration, CBER, CDER, CDRH. Guidance for Clinical Trial Sponsors: Establishment and Operation of Clinical Trial Data Monitoring Committees. 2006 Available from: www.fda.gov/downloads/RegulatoryInformation/Guidances/UCM127073.pdf Date last accessed: December 29, 2009.
-
(2006)
Guidance for Clinical Trial Sponsors: Establishment and Operation of Clinical Trial Data Monitoring Committees
-
-
-
12
-
-
0036399487
-
Comparison of alternative strategies for analysis of longitudinal trials with dropouts
-
DOI 10.1081/BIP-120015744
-
Liu G, Gould AL. Comparison of alternative strategies for analysis of longitudinal trials with dropouts. J Biopharm Stat 2002; 12: 207-226. (Pubitemid 35205022)
-
(2002)
Journal of Biopharmaceutical Statistics
, vol.12
, Issue.2
, pp. 207-226
-
-
Liu, G.1
Gould, A.L.2
-
13
-
-
73849145996
-
The SF-36 and SGRQ: Validity and first look at minimum important differences in IPF
-
Epub ahead of print DOI: 10.1016/j.med.2009.09.006
-
Swigris JJ, Brown KK, Behr J, et al. The SF-36 and SGRQ: validity and first look at minimum important differences in IPF. Respir Med 2009; [Epub ahead of print DOI: 10.1016/j.med.2009.09.006].
-
(2009)
Respir Med
-
-
Swigris, J.J.1
Brown, K.K.2
Behr, J.3
-
14
-
-
77951176083
-
-
InterMune Investor Relations Available from: Date last accessed: December 29, 2009
-
InterMune. Investor Relations. Available from: http://phx. corporate-ir.net/phoenix.zhtml?c5100067&p5irol-IRHome Date last accessed: December 29, 2009.
-
-
-
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