β2-Agonists block tussive responses in guinea pigs via an atypical cAMP-dependent pathway

European Respiratory Journal

Volumn 35, Issue 3, 2010, Pages 647-654

  Freund Michel, V C ^a   Birrell, M A ^a   Giembycz, M A ^b   Hele, D J ^a   Haj Yahia, S ^a   Belvisi, M G ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

2 Adrenoceptor agonist; Airway sensory nerves; Cough; Cyclic adenosine monophosphate; Large conductance calcium activated potassium channels; Protein kinase G

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 8 BROMO CYCLIC AMP; 9 (TETRAHYDRO 2 FURYL)ADENINE; APAMIN; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ACTIVATED POTASSIUM CHANNEL; CAPSAICIN; CLOTRIMAZOLE; CYCLIC AMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; FENOTEROL; FORSKOLIN; GLIBENCLAMIDE; KT 5720; KT 5823; PAXILLINE; ROLIPRAM; TERBUTALINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COUGHING; DEPOLARIZATION; DOSE RESPONSE; DRUG MECHANISM; GUINEA PIG; MALE; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE; SWINE; VAGUS NERVE;

ANIMALS; ANTITUSSIVE AGENTS; BRONCHODILATOR AGENTS; COUGH; CYCLIC AMP; DISEASE MODELS, ANIMAL; GUINEA PIGS; HUMANS; MALE; RECEPTORS, ADRENERGIC, BETA-2; TERBUTALINE; VAGUS NERVE;

EID: 77951163452     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00034009     Document Type: Article

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