Monkeying around with cardiac progenitors: Hope for the future

Journal of Clinical Investigation

Volumn 120, Issue 4, 2010, Pages 1034-1036

  Qian, Li ^a   Srivastava, Deepak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CELL SURFACE MARKER; CYTOKINE; STAGE SPECIFIC EMBRYO ANTIGEN 1;

CELL ISOLATION; ENDOTHELIUM CELL; ENGRAFTMENT; HEART MUSCLE CELL; MESODERM; NONHUMAN; NOTE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; RHESUS MONKEY; SMOOTH MUSCLE FIBER; STEM CELL; TERATOMA;

ANIMALS; ANTIGENS, CD15; CELL DIFFERENTIATION; CELL SEPARATION; EMBRYONIC STEM CELLS; INDUCED PLURIPOTENT STEM CELLS; MACACA MULATTA; MULTIPOTENT STEM CELLS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; STEM CELL TRANSPLANTATION;

EID: 77951157659     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI42643     Document Type: Note

References (17)

1. Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell. 2008;132(4):661-680.
2. Srivastava D, Ivey KN. Potential of stem-cell-based therapies for heart disease. Nature. 2006; 441(7097):1097-1099.
3. Passier R, van Laake LW, Mummery CL. Stem-cell-based therapy and lessons from the heart. Nature. 2008; 453(7193):322-329.
4. Yi BA, Wernet O, Chien KR. Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration. J Clin Invest. 2010; 120(1):20-28.
5. Kattman SJ, Huber TL, Keller GM. Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell. 2006;11(5):723-732.
6. Yang L, et al. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature. 2008;453(7194):524-528.
7. Bu L, et al. Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature. 2009;460(7251):113-117.
8. Laugwitz KL, et al. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature. 2005;433(7026):647-653.
9. Moretti A, et al. Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell. 2006; 127(6):1151-1165.
10. Wu SM, et al. Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell. 2006;127(6):1137-1150.
11. Blin G, et al. A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates. J Clin Invest. 2010;120(4):1125- 1139.
12. Park IH, et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature. 2008;451(7175):141-146.
13. Takahashi K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131(5):861-872.
14. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006; 126(4):663-676.
15. Yu J, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007; 318(5858):1917-1920.
16. van Laake LW, et al. Human embryonic stem cellderived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res. 2007; 1(1):9-24.
17. Laflamme MA, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol. 2007;25(9):1015-1024.