Use of volatile fingerprints for rapid screening of antifungal agents for efficacy against dermatophyte Trichophyton species

Sensors and Actuators, B: Chemical

Volumn 146, Issue 2, 2010, Pages 521-526

  Naraghi, Kamran ^a   Sahgal, Natasha ^a   Adriaans, Beverley ^b   Barr, Hugh ^b   Magan, Naresh ^a  

^a CRANFIELD UNIVERSITY   (United Kingdom)

^b GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

Author keywords

Antifungal compounds; Rapid screening; Trichophyton species; Volatile fingerprints

Indexed keywords

ANTIFUNGAL AGENTS; ANTIFUNGAL COMPOUNDS; ANTIMICROBIAL DRUG; DRUG RESISTANCE; EFFECTIVE CONCENTRATION; ELECTRONIC NOSE (E-NOSE); GROWTH RESPONSE; HEADSPACE ANALYSIS; IN-VITRO; INFECTION CONTROL; MICROBIAL POPULATIONS; MYCELIAL GROWTH; PRINCIPAL COMPONENTS ANALYSIS; PRODUCTION PATTERNS; RAPID SCREENING; SLOW GROWTH; SOLID MEDIA;

ARTIFICIAL ORGANS; CLUSTER ANALYSIS; ELECTRIC CONDUCTIVITY MEASUREMENT; FUNGI; FUNGICIDES; INTELLIGENT AGENTS;

PRINCIPAL COMPONENT ANALYSIS;

EID: 77951110054     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2009.12.031     Document Type: Article

References (19)

1. Cetinkaya Z., Kiraz N., Karaca S., Kulac M., Ciftci I.H., Aktepe O.C., Altindis M., Kiyildi N., and Piyade M. Antifungal susceptibilities of dermatophytic agents isolated from clinical specimens. Eur. J. Dermatol. 15 (2005) 258-261
2. da Silva Barros M.E., de Assis Santos D., and Hamdan J.S. In vitro methods for antifungal susceptibility testing of Trichophyton species. Mycol. Res. 110 (2006) 1355-1360
3. Fend R., Kolk A.H., Bessant C., Buijtels P., Klatser P.R., and Woodman A.C. Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum. J. Clin. Microb. 44 (2006) 2039-2045
4. Gendron K.B., Hockstein N.G., Thaler E.R., Vachani A., and Hanson C.W. In vitro discrimination of tumor cell lines with an electronic nose. Otolaryngol.-Head. Neck Surg. 137 (2007) 269-273
5. Hackett B.C., O'Connell K., Cafferkey M., O'Donnell B.F., and Keane F.M. Tinea capitis in a paediatric population. Irish Med. J. 99 (2006) 294-295
6. Hay R.J., and Moore M.K. Chapter 31: mycology. In: Burns D.A., Griffiths C., Breathnach S.M., and Cox N. (Eds). Rook's Textbook of Dermatology. 7th ed. (2004), Oxford, Blackwell Science Ltd.
7. Lai S.Y., Deffenderfer O.F., Hanson W., Phillips M.P., and Thaler E.R. Identification of upper respiratory bacterial pathogens with the electronic nose. Laryngoscope 112 (2002) 975-979
8. Magan N., and Evans P. Volatiles as an indicator of fungal activity and differentiation between species, and the potential use of electronic nose technology for early detection of grain spoilage. J. Stored Prod. Res. 36 (2000) 319-340
9. Merz W.G., and Hay R.J. Medical mycology. Topley & Wiilson's Microbiology and Microbial Infections. 10th ed. (2005), Hodder Arnold Ltd., London
10. Moens M., Smet A., Naudts B., Verhoeven J., Ieven M., Jorens P., Geise H.J., and Blockhuys F. Fast identification of ten clinically important micro-organisms using an electronic nose. Lett. Appl. Microbiol. 42 (2006) 121-126
11. Pavlou A.K., Magan N., McNulty C., Jones J., Sharp D., Brown J., and Turner A.P.F. Use of an electronic nose system for diagnoses of urinary tract infections. Biosens. Bioelectron. 17 (2002) 893-899
12. Pavlou A.K., Magan N., Jones J.M., Brown J., Klatser P., and Turner A.P.F. Detection of Mycobacterium tuberculosis (TB) in vitro and in situ using an electronic nose in combination with a neural network system. Biosens. Bioelectron. 20 (2004) 538-544
13. Pearce T.C., Schiffman S.S., Nagle H.T., and Gardner J.W. Handbook of Machine Olfaction: Electronic Nose Technology (2003), WILEY-VCH Verlag GmbH & Co., Weinheim
14. Rex J.H., Pfaller M.A., Walsh T.J., et al. Antifungal susceptibility testing: practical aspects and current challenges. Clin. Microbiol. Rev. 14 (2001) 659-688
15. Sahgal N., Monk B., Wasil M., and Magan N. Trichophyton species: use of volatile fingerprints for rapid identification and discrimination. Br. J. Dermatol. 155 (2006) 1209-1216
16. Sahgal N., and Magan N. Fungal volatile fingerprints: discrimination between dermatophyte species and strains by means of an electronic nose. Sens. Actuators B 131 (2008) 117-120
17. Scotter J.M., Langford V.S., Wilson P.F., McEwan M.J., and Chambers S.T. Real-time detection of common microbial volatile organic compounds from medically important fungi by selected ion flow tube-mass spectrometry (SIFT-MS). J. Microbiol. Methods 63 (2005) 127-134
18. Shykhon M.E., Morgan D.W., Dutta R., Hines E.L., and Gardner J.W. Clinical evaluation of the electronic nose in the diagnosis of ear, nose and throat infection: a preliminary study. J. Laryngol. Ontol. 118 (2006) 706-709
19. Turner A.P.F., and Magan N. Electronic noses and disease diagnostics. Nat. Rev. Microbiol. 2 (2004) 161-166