Thrombocytopenia as an adverse effect of complementary and alternative medicines, herbal remedies, nutritional supplements, foods, and beverages

European Journal of Haematology

Volumn 84, Issue 5, 2010, Pages 421-429

  Royer, Derek J ^a   George, James N ^a   Terrell, Deirdra R ^a  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Beverage; Complementary alternative medicine; Drug induced thrombocytopenia; Food; Herbal remedy; Nutritional supplement; Thrombocytopenia

Indexed keywords

ASPARTAME; AZATHIOPRINE; CHROMIUM PICOLINATE; CUPRESSUS FUNEBRIS EXTRACT; FLUOXETINE; IMMUNOGLOBULIN; NAPROXEN; NICOTINAMIDE; NICOTINIC ACID; PARACETAMOL; PLANT EXTRACT; RETINOL PALMITATE; STEROID; THYMUS EXTRACT; UNCLASSIFIED DRUG; XIAO CHAI HU TANG;

ACUTE KIDNEY FAILURE; ALTERNATIVE MEDICINE; ARTICLE; AYURVEDA; BLEEDING; BLOOD LEVEL; BLOOD TRANSFUSION; CRANBERRY JUICE; CREATININE BLOOD LEVEL; CUPRESSUS FUNEBRIS; DEPRESSION; DIET SUPPLEMENTATION; DRUG WITHDRAWAL; ECHINACEA PALLIDA; HEMOLYTIC ANEMIA; HUMAN; HYPERICUM PERFORATUM; HYPERPHOSPHATEMIA; LEUKOPENIA; LIVER TOXICITY; LUPINUS TERMIS; MEDICINAL PLANT; MILK; PLASMAPHERESIS; PRIORITY JOURNAL; SESAME; SIDE EFFECT; TEA; THROMBOCYTOPENIA; THROMBOCYTOPENIC PURPURA;

BEVERAGES; DIETARY SUPPLEMENTS; FOOD; HERBAL MEDICINE; HUMANS; THROMBOCYTOPENIA;

EID: 77951087308     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2010.01415.x     Document Type: Article

References (49)

1. De Smet PAGM. Herbal remedies. N Engl J Med 2002 347 : 2046 2056.
2. Molassiotis A, Fernadez-Ortega P, Pud D, et al. Use of complementary and alternative medicine in cancer patients: a European survey. Ann Oncol 2005 16 : 655 663. (Pubitemid 40613334)
3. Barnes PM, Bloom B, Nahin RL. Complementary and Alternative Medicine Use Among Adults and Children: United States, 2007.
4. Mainardi T, Kapoor S, Bielory L. Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effects. J Allergy Clin Immunol 2009 123 : 283 294.
5. Aster RH, Bougie DW. Drug-induced immune thrombocytopenia. N Engl J Med 2007 357 : 580 587.
6. Aster RH, Curtis BR, McFarland JG, Bougie DW. Durg-induced immune thrombocytopenia: pathogenesis, diagnosis and management. J Thromb Haemost 2009 7 : 911 918.
7. Niggemann B, Grüber C. Side-effects of complementary and alternative medicine. Allergy 2003 58 : 707 716.
8. Kaufman DW, Kelly JP, Johannes CB, Sandler A, Harmon D, Stolley PD, Shapiro S. Acute thrombocytopenic purpura in relation to the use of drugs. Blood 1993 82 : 2714 2718.
9. George JN, Raskob GE, Shah SR, Rizvi MA, Hamilton SA, Osborne S, Vondracek T. Drug-induced thrombocytopenia: a systematic review of published case reports. Ann Intern Med 1998 129 : 886 890.
10. Swisher KK, Li X, Vesely SK, George JN. Drug-induced thrombocytopenia. An updated systematic review, 2008. Drug Saf 2009 32 : 85 6.
11. Brvar M, Kozelj G, Mozina M, Bunc M. Acute poisoning with autum crocus (Colchicum autumnale). Wien Klin Wochenschr 2004 116 : 205 208.
12. Volcy J, Nzerue CM, Oderinde A, Hewen-Iowe K. Cocaine-induced acute renal failure, hemolysis, and thrombocytopenia mimicking thrombotic thrombocytopenic purpura. Am J Kidney Dis 2000 35 : 1 5.
13. Christie DJ, Walker RH, Kolins MD. Quinine-induced thrombocytopenia following intravenous use of heroin. Arch Intern Med 1983 143 : 1174.
14. Aubourg P, Adamsbaum C, Lavallard-Rosseau M-C, et al. A two-year trial of oleic and erucic acids ("Lorenzo's Oil") as treatment for adrenomyeloneuropathy. N Engl J Med 1993 329 : 745 752.
15. Lorenzo's Oil. The Myelin Project 2009 Nov 3. http://www.myelin.org/en/ cms/?293.
16. Belkin GA. Cocktail purpura an unusual case of quinine sensitivity. Ann Intern Med 1967 66 : 583 586.
17. Eisner EV, Korbitz BC. Quinine-induced thrombocytopenic purpura due to an IgM and an IgG antibody. Transfusion 1972 12 : 317 321.
18. Korbitz BC, Eisner E. Cocktail purpura. Quinine-dependent thrombocytopenia. Rocky Mt Med J 1973 70 : 38 41.
19. Siroty RR. Purpura on the rocks - with a twist. JAMA 1976 235 : 2521.
20. Murray JA, Abbott I, Anderson DA, Morgan AD. Bitter lemon purpura. BMJ 1979 2 : 1551 1552.
21. Brasic JR. Quinine-induced thrombocytopenia in a 64-year-old man who consumed tonic water to relieve nocturnal leg cramps. Mayo Clin Proc 2001 76 : 863 864.
22. Caffrey EA, Sladen GE, Isaacs PET, Clark KGA. Thrombocytopenia caused by cow's milk. Lancet 1981 2 : 316.
23. Davies JK, Ahktar N, Ranasinge E. A juicy problem. Lancet 2001 358 : 2126.
24. Azuno Y, Yaga K, Sasayama T, Kimoto K. Thrombocytopenia induced by Jui, a traditional Chinese herbal medicine. Lancet 1999 354 : 304 305.
25. Ohmori T, Nishii K, Hagihara A, Takeda M, Sekido K. Acute thrombocytopenia induced by Jui, a traditional herbal medicine. J Thromb Haemost 2004 2 : 1479 1480.
26. Lavy R. Thrombocytopenic purpura due to Lupinus termis bean. J Allergy Clin Immunol 1964 35 : 386 388.
27. Arnold J, Ouwehand WH, Smith G, Cohen H. A young woman with petechiae. Lancet 1998 352 : 618.
28. Kao WF, Hung DZ, Tsai WJ, Lin KP, Deng JF. Podophyllotoxin intoxication: toxic effect of Bajiaolian in herbal therapeutics. Hum Exp Toxicol 1992 11 : 480 487.
29. Lee JJ, Chen HC. Flavonoid-induced acute neuropathy by Cupressus funebris Endl (Mourning Cypress). Am J Kidney Dis 2006 48 : e81 5.
30. Squier TL, Madison FW. Thrombocytopenic purpura due to food allergy. J Allergy 1937 8 : 143 154.
31. Perrotta S, Nobili B, Rossi F, Criscuolo M, Iolascon A, Pinto D, Passaro I, Cennamo L, Oliva A, Ragione F. Infant hypervitaminosis A causes severe anemia and thrombocytopenia: evidence of a retinol-dependent bone marrow cell growth inhibition. Blood 2002 99 : 2017 2022.
32. Kojouri K, Vesely SK, George JN. Quinine-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: frequency, clinical features, and long-term outcomes. Ann Intern Med 2001 135 : 1047 1051.
33. Cerrulli J, Grabe DW, Gauthier I, Malone M, McGoldrick MD. Chromium picolinate toxicity. Ann Pharmacother 1998 32 : 428 431.
34. George L, Ioannis E, Radostina T, Antonios M. Severe thrombotic thrombocytopenic purpura (TTP) induced or exacerbated by the immunostimulatory herb Echinacea. Am J Hematol 2006 81 : 224.
35. Demiroglu YZ, Yeter TT, Boga C, Ozdogu H, Kizilkilic E, Bal N, Tuncer I, Arslan H. Bone marrow necrosis: a rare complication of herbal treatment with Hypericum perforatum (St. John's Wort). Acta Med 2005 48 : 91 4.
36. Takahashi Y, Tanaka A, Nakamura T, Fukuwatari T, Shibata K, Shimada N, Ebihara I, Koide H. Nicotinamide suppresses hyperphosphatemia in hemodialysis patients. Kidney Int 2004 65 : 1099 1104.
37. Raymond RS, Fallon MB, Abrams GA. Oral thymic extract for chronic hepatitis C in patients previously treated with interferon. Ann Intern Med 1998 129 : 797 800.
38. Pye KG, Kelsey SM, House IM, Newland AC. Severe dyserythropoiesis and autoimmune thrombocytopenia associated with ingestion of kelp supplements. Lancet 1992 339 : 1540.
39. Whitfield MF, Barr DG. Cows' milk allergy in the syndrome of thrombocytopenia with absent radius. Arch Dis Child 1976 51 : 337 343.
40. Jones RH. Congenital thrombocytopenia and milk allergy. Arch Dis Child 1977 52 : 744 745.
41. O'Brien T, Silverberg JD, Nguyen TT. Nicotinic acid-induced toxicity associated with cytopenia and decreased levels of thyroxine-binding globulin. Mayo Clin Proc 1992 67 : 465 468.
42. Smereck J. Aplastic anemia: a possible toxic effect of an herbal "colon cleansing" preparation. J Emerg Med 2009 36 : 191 193.
43. Roberts HJ. Aspartame-induced thrombocytopenia. South Med J 2007 100 : 543.
44. Taylor DM, Walsham N, Taylor SE, Wong L. Use and toxicity of complementary and alternative medicines among emergency department patients. Emerg Med Australas 2004 16 : 400 406.
45. Parab S, Kulkarni R, Thatte U. Heavy metals in 'herbal' medicines. Indian J Gastroenterol 2003 22 : 111 112.
46. Reimund E, Ramos A. Niacin-induced hepatitis and thrombocytopenia after 10 years of niacin use. J Clin Gastroenterol 1994 18 : 270 271.
47. Rottemburg JB, Launay-Vacher V, Massard J. Thrombocytopenia induced by nicotinamide in hemodialysis patients. Kidney Int 2005 68 : 2911 2912.
48. Kiguchi T, Kimura F, Kiiya K, Katayama Y, Harada M. Acute thrombocytopenic purpura after ingestion of Sho-saiko-to for hepatitis. Liver 2000 20 : 491.
49. Lowenthal MN, Jones IG, Desai M. Aplastic anaemia and optic fundus haemorrhages due to traditional herbal remedies. J Trop Med Hyg 1978 81 : 177 179.