Concomitant cisplatin, paclitaxel, and hyperfractionated radiotherapy in locally advanced head and neck cancer: Comparison of two different schedules

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 33, Issue 2, 2010, Pages 137-143

  Moreno Jiménez, Marta ^a   Valero, Jeannette ^a   María López Picazo, José ^a   Arbea, Leire ^a   Aristu, Javier ^a   Cambeiro, Mauricio ^a   Alcalde, Juan ^b   Martínez Monge, Rafael ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Advanced head and neck cancer; Altered fractionation; Concurrent cisplatin; Concurrent paclitaxel; Concurrent radiochemotherapy

Indexed keywords

CARBOPLATIN; CISPLATIN; PACLITAXEL;

ACUTE KIDNEY FAILURE; ADULT; ADVANCED CANCER; AGED; ANEMIA; ARTICLE; CANCER RECURRENCE; CHEMOTHERAPY INDUCED EMESIS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; DERMATITIS; DRUG EFFICACY; DRUG TREATMENT FAILURE; DYSPHAGIA; FEMALE; FIBROSIS; HEAD AND NECK CARCINOMA; HUMAN; HYPOPHARYNX TUMOR; INFECTION; INTENSITY MODULATED RADIATION THERAPY; L HERMITTE SYNDROME; LARYNX TUMOR; LEUKOPENIA; MALE; MOUTH TUMOR; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NAUSEA; NECK DISSECTION; NECK FIBROSIS; NEUROLOGIC DISEASE; OROPHARYNX TUMOR; OVERALL SURVIVAL; PARANASAL SINUS TUMOR; PNEUMONIA; RADIATION DOSE; SALIVARY GLAND TUMOR; SQUAMOUS CELL CARCINOMA; THROMBOCYTOPENIA; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR LOCALIZATION; XEROSTOMIA;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; COMBINED MODALITY THERAPY; DOSE FRACTIONATION; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PACLITAXEL; PROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 77951086580     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/COC.0b013e31819d369d     Document Type: Article

References (31)

1. Fu KK, Pajak TF, Trotti A, et al. A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys. 2000;48:7-16.
2. Horiot JC, Le Fur R, N'Guyen T, et al. Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a random- ized trial of the EORTC cooperative group of radiotherapy. Radiother Oncol. 1992;25:231-241.
3. Marcial VA, Pajak TF, Mohiuddin M, et al. Concomitant cisplatin chemotherapy and radiotherapy in advanced mucosal squamous cell carcinoma of the head and neck. Long-term results of the Radiation Therapy Oncology Group study 81-17. Cancer. 1990;66:1861-1868.
4. Pinto LH, Canary PC, Araujo CM, et al. Prospective randomized trial comparing hyperfractionated versus conventional radiotherapy in stages III and IV oropharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 1991;21: 557-562.
5. Sanchiz F, Milla A, Torner J, et al. Single fraction per day versus two fractions per day versus radiochemotherapy in the treatment of head and neck cancer. Int J Radiat Oncol Biol Phys. 1990;19:1347-1350.
6. Stuschke M, Thames HD. Hyperfractionated radiotherapy of human tumors: overview of the randomized clinical trials. Int J Radiat Oncol Biol Phys. 1997;37:259-267.
7. Adelstein DJ, Saxton JP, Lavertu P, et al. A phase III randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer: preliminary results. Head Neck. 1997;19:567-575. (Pubitemid 27407310)
8. Bachaud JM, Cohen-Jonathan E, Alzieu C, et al. Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: final report of a randomized trial. Int J Radiat Oncol Biol Phys. 1996;36:999-1004.
9. Brizel DM, Albers ME, Fisher SR, et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med. 1998;338:1798-1804.
10. Calais G, Alfonsi M, Bardet E, et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst. 1999;91:2081-2086.
11. Carter DL, Asmar L, Barrera D, et al. Two years survival for recurrent carboplatin, paclitaxel and hyperfractioned radiotherapy in unresectable head and neck cancer. Proc Am Soc Clin Oncol. 2003.
12. Carter K, Settle K, Taylor R, et al. Site as a prognostic factor in patients with stage III/IV squamous cell carcinoma of the head and neck following definitive chemoradiation. Int J Radiat Oncol Biol Phys. 2007;69(suppl 2481):S468.
13. Cupino A, Anne R, Axelrod R, et al. Is IMRT superior to 3D conformal radiotherapy for locally advanced head and neck cancer treated with aggressive concurrent cisplatin/taxane chemotherapy? Int J Radiat Oncol Biol Phys. 2007;69(suppl 2380):S415.
14. Díaz R, Thorpe SW, Murphy BA, et al. Intensity-modulated radiation therapy (IMRT) with concurrent taxane-based chemotherapy for locally-advanced head and neck cancer (LAHNC): toxicities and efficacy. Int J Radiat Oncol Biol Phys. 2007;69:S464.
15. Duggan D, Murphy BA, Beach M, et al. Intensity-modulated radiation therapy (IMRT) with taxane-based chemotherapy for locally-advanced head and neck cancer (LAHANC): feasibility, technique, and toxicities. Proc Am Soc Clin Oncol. Vol.23, 39th Annual Meeting, 2003.
16. Garden AS, Harris J, Vokes EE, et al. Preliminary results of Radiation Therapy Oncology Group 97-03: a randomized phase ii trial of concurrent radiation and chemotherapy for advanced squamous cell carcinomas of the head and neck. J Clin Oncol. 2004;22:2856-2864.
17. Suntharalingam M, Haas ML, Conley BA, et al. The use of carboplatin and paclitaxel with daily radiotherapy in patients with locally advanced squamous cell carcinomas of the head and neck. Int J Radiat Oncol Biol Phys. 2000;47:49-56.
18. Escrivá de Romaní S, Moreno M, et al. Paclitaxel and cisplatin combination with hyperfractioned radiotherapy in locally advanced head and neck cancer. Proc Am Soc Clin Oncol. Vol.22, 39th Annual Meeting, 2003.
19. Valero J, Aristu J, Cambeiro M, et al. Initial results of a prospective clinical study of cisplatin/paclitaxel based hyperfractionated chemoradiation (3DCRTHF) in squamous cell head and neck cancer (HNC) stages III-IV. Eur J Cancer Suppl. 2005;3:305-306.
20. American Joint Committee on Cancer. Manual for Staging of Cancer. 5th ed. Philadelphia, PA: American Joint Committee on Cancer; 1997.
21. International Commission on Radiation Units and Measurements: Prescribing, Recording, and Reporting Photon Beam Therapy. Bethesda, MD: International Commission on Radiation Units and Measurements; 1993. ICRU Report 50.
22. International Commission on Radiation Units and Measurements. Prescribing, Recording, and Reporting Photon Beam Therapy [Supplement to ICRU Report 50]. Bethesda, MD: 1999. International Commission on Radiation Units and Measurements. ICRU Report 62.
23. Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS, March 31, 2003. Available at: http://ctep.cancer.gov. Accessed August 9, 2006.
24. Miller AB, Hoogstraten B, Staquet M, et al. Reporting results of cancer treatment. Cancer. 1981;47:207-214.
25. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
26. Cox DR, Oakes D. Analysis of Survival Data. London: Chapman and Hall; 1984.
27. Suntharalingam M, Haas ML, Van Echo DA, et al. Predictors of response and survival after concurrent chemotherapy and radiation for locally advanced squamous cell carcinomas of the head and neck. Cancer. 2001;91:548-554.
28. Cmelak AJ, Murphy BA, Burkey B, et al. Taxane-based chemoirradiation for organ preservation with locally advanced head and neck cancer: results of a phase II multi-institutional trial. Head Neck. 2007;29:315-324.
29. Bernier J. A multidisciplinary approach to squamous cell carcinomas of the head and neck: an update. Curr Opin Oncol. 2008, 20:249-255.
30. Feher O, Martins SJ, Lima CA, et al. Pilot trial of concomitant chemotherapy with paclitaxel and split-course radiotherapy for very advanced squamous cell carcinoma of head and neck. Head Neck. 2002;24:228-235.
31. Wendt TG, Grabenbauer GG, Rodel CM, et al. Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study. J Clin Oncol. 1998;16:1318-1324.