Continuous CD27 triggering in vivo strongly reduces NK cell numbers

European Journal of Immunology

Volumn 40, Issue 4, 2010, Pages 1107-1117

  De Colvenaer, Veerle ^a   Taveirne, Sylvie ^a   Hamann, Jörg ^b   De Bruin, Alex M ^b   De Smedt, Magda ^a   Taghon, Tom ^a   Vandekerckhove, Bart ^a   Plum, Jean ^a   Van Lier, René ^b   Leclercq, Georges ^a  

^a GHENT UNIVERSITY   (Belgium)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

CD70 Tg mice; Cytotoxicity; Differentiation

Indexed keywords

CD27 ANTIGEN; CD70 ANTIGEN; GAMMA INTERFERON; LYSINE;

ANIMAL CELL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL COUNT; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; FEMALE; IN VIVO STUDY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION;

ANIMALS; ANTIGENS, CD27; ANTIGENS, CD70; ANTIGENS, LY; APOPTOSIS; B-LYMPHOCYTES; CROSSES, GENETIC; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; GENE EXPRESSION REGULATION; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE COUNT; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; RECEPTORS, IMMUNOLOGIC; SPLEEN;

EID: 77951074735     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939251     Document Type: Article

References (43)

1. Moretta, A., Bottino, C., Mingari, M. C., Biassoni, R. and Moretto, L., What is a natural killer cell? Nat. Immunol. 2002. 3: 6-8. (Pubitemid 34065607)
2. Raulet, D. H., Interplay of natural killer cells and their receptors with the adaptive immune response. Nat. Immunol. 2004. 5: 996-1002.
3. Kagi, D., Ledermann, B., Burki, K., Seiler, P., Odermatt, B., Olsen, K. J., Podack, E. R. et al., Cytotoxicity Mediated by T-cells and natural-killer-ells is greatly impaired in perforin deficient mice. Nature 1994. 369: 31-37. (Pubitemid 24144352)
4. Shresta, S., Macivor, D. M., Heusel, J. W., Russell, J. H. and Ley, T. J., Natural-killer and lymphokine-activated killer-cells require granzyme-B for the rapid induction of apoptosis in susceptible target-cells. Proc. Natl. Acad. Sci USA 1995. 92: 5679-5683.
5. Bradley, M., Zeytun, A., Rafi-Janajreh, A., Nagarkatti, P. S. and Nagarkatti, M., Role of spontaneous and interleukin-2-induced natural killer cell activity in the cytotoxicity and rejection of Fas(+) and Fas(-) tumor cells. Blood 1998. 92: 4248-4255. (Pubitemid 28544341)
6. Screpanti, V.,Wallin, R. P. A., Ljunggren, H. G. and Grandien, A., A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells. J. Immunol. 2001. 167: 2068-2073. (Pubitemid 32747514)
7. Takeda, K., Cretney, E., Hayakawa, Y., Ota, T., Akiba, H., Ogasawara, K., Yagita, H. et al., TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood 2005. 105: 2082-2089. (Pubitemid 40731795)
8. Arase, H., Arase, N. and Saito, T., Interferon gamma production by natural killer (NK) cells and NK1.1(1) T cells upon NKR-P1 cross-linking. J. Exp. Med. 1996. 183: 2391-2396.
9. Kim, S. and Yokoyama, W. M., NK cell granule exocytosis and cytokine production inhibited by Ly-49A engagement. Cell. Immunol. 1998. 183: 106-112.
10. Ho, E. L., Carayannopoulos, L. N., Poursine-Laurent, J., Kinder, J., Plougastel, B., Smith, H. R. C. and Yokoyama, W. M., Costimulation of multiple NK cell activation receptors by NKG2D. J. Immunol. 2002. 169: 3667-3675.
11. Ortaldo, J. R. and Young, H. A., Expression of IFN-gamma upon triggering of activating Ly49D NK receptors in vitro and in vivo: Costimulation with IL-12 or IL-18 overrides inhibitory receptors. J. Immunol. 2003. 170: 5799.
12. Lanier, L. L., NK cell recognition. Annu. Rev. Immunol. 2005. 23: 225-274.
13. Kondo, M., Weissman, I. L. and Akashi, K., Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997. 91: 661-672. (Pubitemid 27513657)
14. Moore, T., Bennett, M. and Kumar, V., Transplantable NK cell progenitors in murine bone-marrow. J. Immunol. 1995. 154: 1653-1663.
15. Hackett, J., Bosma, G. C., Bosma, M. J., Bennett, M. and Kumar, V., Transplantable progenitors of natural-killer-cells are distinct from those of T and B Lymphocytes. Proc. Natl. Acad. Sci. USA 1986. 83: 3427-3431.
16. Rolink, A., tenBoekel, E., Melchers, F., Fearon, D. T., Krop, I. and Andersson, J., A subpopulation of B220(1) cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors. J. Exp. Med. 1996. 183: 187-194.
17. Rosmaraki, E. E., Douagi, I., Roth, C., Colucci, F., Cumano, A. and Di Santo, J. P., Identification of committed NK cell progenitors in adult murine bone marrow. Eur. J. Immunol. 2001. 31: 1900-1909.
18. Kim, S., Iizuka, K., Kang, H. S. P., Dokun, A., French, A. R., Greco, S. and Yokoyama, W. M., In vivo developmental stages in murine natural killer cell maturation. Nat. Immunol. 2002. 3: 523-528.
19. Di Santo, J. P., Natural killer cell developmental pathways: A question of balance. Annu. Rev. Immunol. 2006. 24: 257-286.
20. Nieto, M., Rodriguez-Fernandez, J. L., Navarro, F., Sancho, D., Frade, J. M. R., Mellado, M., Martinez-A, C. et al., Signaling through CD43 induces natural killer cell activation, chemokine release, and PYK-2 activation. Blood 1999. 94: 2767-2777. (Pubitemid 29477305)
21. Xia, Y., Vetvicka, V., Yan, J., Hanikyrova, M., Mayadas, T. and Ross, G. D., The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J. Immunol. 1999. 162: 2281-2290. (Pubitemid 29288852)
22. Hayakawa, Y. and Smyth, M. J., CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J. Immunol. 2006. 176: 1517-1524. (Pubitemid 43134295)
23. van Lier, R. A. W., Borst, J., Vroom, T. M., Klein, H., Vanmourik, P., Zeijlemaker, W. P. and Melief, C. J. M., Tissue distribution and biochemical and functional-properties of Tp55 (CD27), a novel T-cell differentiation Antigen. J. Immunol. 1987. 139: 1589-1596. (Pubitemid 17141574)
24. Gravestein, L. A., Amsen, D., Boes, M., Calvo, C. R., Kruisbeek, A. M. and Borst, J., The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2. Eur. J. Immunol. 1998. 28: 2208-2216.
25. Gravestein, L. A. and Borst, J., Tumor necrosis factor receptor family members in the immune system. Semin. Immunol. 1998. 10: 423-434.
26. Borst, J., Hendriks, J. and Xiao, Y. L., CD27 and CD70 in T cell and B cell activation. Curr. Opin. Immunol. 2005. 17: 275-281.
27. Hintzen, R. Q., Lens, S. M., Beckmann, M. P., Goodwin, R. G., Lynch, D. and van Lier, R. A. W., Characterization of the human CD27 ligand, a novel member of the TNF gene family. J. Immunol. 1994. 152: 1762-1773. (Pubitemid 24075708)
28. Nolte, M. A., Arens, R., van Os, R., van Oosterwijk, M., Hooibrink, B., van Lier, R. A. W. and van Oers, M. H. J., Immune activation modulates hematopoiesis through interactions between CD27 and CD70. Nat. Immunol. 2005. 6: 412-418.
29. Arens, R., Tesselaar, K., Baars, P. A., van Schijndel, G. M.W., Hendriks, J., Pals, S. T., Krimpenfort, P. et al., Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFN gamma-mediated B cell depletion. Immunity 2001. 15: 801-812. (Pubitemid 34008507)
30. Tesselaar, K., Arens, R., van Schijndel, G. M.W., Baars, P. A., van der Valk, M. A., Borst, J., van Oers, M. H. J. and van Lier, R. A. W., Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions. Nat. Immunol. 2003. 4: 295.
31. Takeda, K., Oshima, H., Hayakawa, Y., Akiba, H., Atsuta, M., Kobata, T., Kobayashi, K. et al., CD27-mediated activation of murine NK cells. J. Immunol. 2000. 164: 1741-1745.
32. Van Beneden, K., Stevenaert, F., De Creus, A., Debacker, V., De Boever, J., Plum, J. and Leclercq, G., Expression of Ly49E and CD94/NKG2 on fetal and adult NK cells. J. Immunol. 2001. 166: 4302-4311. (Pubitemid 32233710)
33. Diefenbach, A., Jamieson, A. M., Liu, S. D., Shastri, N. and Raulet, D. H., Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat. Immunol. 2000. 1: 119-126.
34. Waizer, T., Bléry, M., Chaix, J., Fuseri, N., Chasson, L., Robbins, S. H., Jaeger, S. et al., Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. . Proc. Natl. Acad. Sci. USA. 2007. 104: 3384-3389.
35. Wiemann, K., Mittrucker, H.W., Feger, U.,Welte, S. A., Yokoyama,W. M., Spies, T., Rammensee, H. G. and Steinle, A., Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo. J. Immunol. 2005. 175: 720-729. (Pubitemid 41094952)
36. Tripathy, S. K., Smith, H. R. C., Holroyd, E. A., Pingel, J. T. and Yokoyama, W. M., Expression of m157, a murine cytomegalovirus-encoded putative major histocompatibility class I (MHC-I)-like protein, is independent of viral regulation of host MHC-I. J. Virol. 2006. 80: 545-550.
37. Di Santo, J. P. and Vosshenrich, C. A. J., Bone marrow versus thymic pathways of natural killer cell development. Immunol. Rev. 2006. 214: 35-46.
38. Samson, S. I., Richard, O., Tavian, M., Ranson, T., Vosshenrich, C. A. J., Colucci, F., Buer, J. et al., GATA-3 promotes maturation, IFN-gamma production, and liver-specific homing of NK cells. Immunity 2003. 19: 701-711.
39. Taki, S., Nakajima, S., Ichikawa, E., Saito, T. and Hida, S., IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells. J. Immunol. 2005. 174: 6005-6012. (Pubitemid 40663787)
40. Townsend, M. J., Weinmann, A. S., Matsuda, J. L., Salomon, R., Farnham, P. J., Biron, C. A., Gapin, L. and Glimcher, L. H., T-bet regulates the terminal maturation and homeostasis of NK and V alpha 14i NKT cells. Immunity 2004. 20: 477-494. (Pubitemid 38482125)
41. Samson, S. I., Memet, S., Vosshenrich, C. A. J., Colucci, F., Richard, O., Ndiaye, D., Israel, A. and Di Santo, J. P., Combined deficiency in IkappaBalpha and IkappaBepsilon reveals a critical window of NF-kappa B activity in natural killer cell differentiation. Blood 2004. 103: 4573-4580. (Pubitemid 38745985)
42. Roder, J. C., Kiessling, R., Biberfeld, P. and Andersson, B., Target-effector interaction in natural killer (NK) cell system. Isolation of NK-cells and studies on mechanism of killing. J. Immunol. 1978. 121: 2509-2517.
43. Arens, R., Schepers, K., Nolte, M. A., van Oosterwijk, M. F., van Lier, R. A. W., Schumacher, T. N. M. and van Oers, M. H. J., Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8(+) T cell formation. J. Exp. Med. 2004. 199: 1595-1605.