Local electrical stimulation of single adherent cells using three-dimensional electrode arrays with small interelectrode distances

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Volumn , Issue , 2009, Pages 2756-2759

  Braeken, Dries ^a   Huys, Roeland ^a   Jans, Danny ^a,b   Loo, Josine ^a   Severi, Simone ^a   Vleugels, Frank ^a   Borghs, Gustaaf ^a   Callewaert, Geert ^b   Bartic, Carmen ^a  

^a IMEC   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRODES;

CALCIUM IMAGING; ELECTRICAL FIELD; ELECTRICAL STIMULATIONS; ELECTROPORATION; GENETIC MANIPULATIONS; INTERELECTRODE DISTANCE; PROPIDIUM IODIDE; THREE-DIMENSIONAL ELECTRODE;

MOLECULAR BIOLOGY;

EID: 77951062094     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2009.5333871     Document Type: Conference Paper

References (12)

1. A. Stett, U. Egert, E. Guenther, F. Hofmann, T. Meyer, W. Nisch and H. Haemmerle, "Biological application of microelectrode arrays in drug discovery and basic research," Anal. Bioanal. Chem. 377 (3): 486-495, 2003.
2. L. Berdondini, P. Massobrio, M. Chiappalone, M. Tedesco, K. Imfeld, A. Maccione, M. Gandolfo, M. Koudelka-Hep and S. Martinoia, "Extracellular recordings from locally dense microelectrode arrays coupled to dissociated cortical cultures," J. Neurosci. Meth. 177 (2): 386-396, 2009.
3. J. K. Y. Law, C. K. Yeung, B. Hofmann, S. Ingebrandt, J. A. Rudd, A. Offenhausser and M. Chan, "The use of microelectrode array (MEA) to study the protective effects of potassium channel openers on metabolically compromised HL-1 cardiomyocytes," Physiol. Meas. 30 (2): 155-167, 2009.
4. Y. Berdichevsky, H. Sabolek, J. B. Levine, K. J. Staley and M. L. Yarmush, "Microfluidics and multielectrode array-compatible organotypic slice culture method," J. Neurosci. Meth. 178 (1): 59-64, 2009.
5. Y. C. Lin, M. Li and C. C. Wu, "Simulation and experimental demonstration of the electric field assisted electroporation microchip for in vitro gene delivery enhancement," Lab Chip 4 (2): 104-108, 2004.
6. T. Jain, J. and Muthuswamy, "Microelectrode array (MEA) platform for targeted neuronal transfection and recording," IEEE Trans. Biomed. Eng. 55 (2): 827-832, 2008.
7. B. Van Meerbergen, J. Loo, R. Huys, T. Raemaekers, K. Winters, D. Braeken, Y. Engelborghs, W. Annaert, G. Borghs and C. Bartic, "Functionalised microneedles for enhanced neuronal adhesion," J. Exp. Nanosci. 3 (2): 147-156, 2008.
8. D. Braeken, D. Jans, D. Rand, R. Huys, B. Van Meerbergen, J. Loo, G. Borghs, G. Callewaert and C. Bartic, "Local Electrical Stimulation of Cultured Embryonic Cardiomyocytes with Sub-micrometer Nail structures," 30th Annual Internat. Conf. of the IEEE Eng. Med. Biol. Soc., 1-8: 4816-4819, 2008.
9. R. Huys, D. Braeken, B. Van Meerbergen, K. Winters, W. Eberle, J. Loo, D. Tsvetanova, C. Chen, S. Severi, S. Yitzchaik, M. Spira, J. Shappir, G. Callewaert, G. Borghs and C. Bartic, "Novel concepts for improved communication between nerve cells and silicon electronic devices," Solid-State Elect. 52(4): 533-539, 2008.
10. M. Krause, S. Ingebrandt, D. Richter, M. Denyer, M. Scholl, C. Sprossler and A. Offenhausser, "Extended gate electrode arrays for extracellular signal recordings," Sens. Actuat. B Chem. 70 (1-3): 101-107, 2000.
11. K. Maswiwat, D. Wachner and J. Gimsa, "Effects of cell orientation and electric field frequency on the transmembrane potential induced in ellipsoidal cells," Bioelectrochem. 74 (1): 130-141, 2008.
12. M. N. Teruel and T. Meyer, "Electroporation-induced formation of individual calcium entry sites in the cell body and processes of adherent cells," 73 (4): 1785-1796, 1997.