In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence

Biomaterials

Volumn 31, Issue 17, 2010, Pages 4613-4619

  Ramseyer, Pascal ^a   Micol, Lionel A ^b   Engelhardt, Eva Maria ^b   Osterheld, Maria Chiara ^a   Hubbell, Jeffrey A ^b   Frey, Peter ^a,b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

Bladder; Hydrogel; Polyacrylonitrile; Swelling; Urinary tract

Indexed keywords

ADIPOCYTES; BLADDER; BULKING AGENTS; FOREIGN BODY REACTIONS; IN-VIVO; MINI-PIG; THERAPEUTIC EFFECTS; TIME POINTS; URINARY INCONTINENCE; URINARY TRACT;

GLYCEROL; WASTE MANAGEMENT;

HYDROGELS;

BULKING AGENT; GLYCEROL; POLYACRYLONITRILE;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; HISTIOCYTE; HISTOPATHOLOGY; IN VIVO STUDY; METAPLASIA; MINIPIG; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; URINE INCONTINENCE; UROTHELIUM;

ACRYLIC RESINS; ANIMALS; HYDROGEL; INJECTIONS; SWINE; URINARY INCONTINENCE;

ANIMALIA;

EID: 77951060073     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.02.021     Document Type: Article

References (10)

1. Norton P., Brubaker L. Urinary incontinence in women. Lancet 2006, 7(367):57-67.
2. Frey P., Lutz N., Jenny P., Herzog B. Endoscopic subureteral collagen injection for the treatment of vesicoureteral reflux in infants and children. J Urol 1995, 154(2):804-807.
3. Kotb A.F., Campeau L., Corcos J. Urethral bulking agents: techniques and outcomes. Curr Urol Rep 2009, 10(5):396-400.
4. Puri P., Chertin B., Velayudham M., Dass L., Colhoun E. Treatment of vesicoureteral reflux by endoscopic injection of dextranomer/hyaluronic acid copolymer: preliminary results. J Urol 2003, 170:1541-1544.
5. Joyner B.D., Atala A. Endoscopic substances for the treatment of vesicouretral reflux. Urology 1997, 50(4):489-494.
6. Ramseyer P., Meagher-Villemure K., Burki M., Frey P. (Poly)acrylonitrile-based hydrogel as a therapeutic bulking agent in urology. Biomaterials 2007, 28:1185-1190.
7. Fockens P., Bruno M.J., Gabbrielli A., Odegaard S., Hatlebakk J., Allescher H.D., et al. Endoscopic augmentation of the lower esophageal sphincter for the treatment of gastroesophageal reflux disease: multicenter study of the Gatekeeper®; reflux repair system. Endoscopy 2004, 36:682-689.
8. Fockens P. Gatekeeper® reflux repair system: technique, pre-clinical, and clinical experience. Gastrointest Endoscopy Clin N Am 2003, 13:179-189.
9. Ray C.D. The PDN® prosthetic disc-nucleus device. Eur Spine J 2002, 11(Suppl. 2):S137-S142.
10. Smith D.P., Kaplan W.E., Oyasu R. Evaluation of polydimethylsiloxane as an alternative in the endoscopic treatment of vesicoureteral reflux. J Urol 1994, 152(4):1221-1224.