Investigating the link between pulp mill effluent and endocrine disruption: Attempts to explain the presence of intersex fish in the Wabigoon River, Ontario, Canada

Environmental Toxicology and Chemistry

Volumn 29, Issue 4, 2010, Pages 952-965

  Pollock, Michael S ^a   Dubé, Monique G ^a   Schryer, Richard ^b  

^a University of Saskatchewan   (Canada)

^b Schryer Environmental Consulting Saskatoon   (Canada)

Author keywords

Endocrine disruption; Fathead minnow; Hypoxia; Pulp mill effluent; Walleye

Indexed keywords

DISSOLUTION; DISSOLVED OXYGEN; EFFLUENTS; FISH; KRAFT PROCESS; MEATS; PAPER AND PULP MILLS; RIVERS; SURVEYS; WASTEWATER;

BLEACHED KRAFT PULPS; CUMULATIVE EFFECTS ASSESSMENTS; DROUGHT CONDITIONS; EFFLUENT CONCENTRATIONS; EFFLUENT VOLUME; ENDOCRINE DISRUPTERS; ENDOCRINE DISRUPTION; FATHEAD MINNOW; FIELD EXPERIMENT; FIELD SURVEYS; FISH SURVEY; HORMONE LEVELS; LOW DISSOLVED OXYGEN; LOW FLOW; MESOCOSMS; MUNICIPAL WASTEWATERS; ONTARIO; ONTARIO , CANADA; PIMEPHALES PROMELAS; PULP MILL EFFLUENT; REPRODUCTIVE EFFECTS; SEDIMENT CONTAMINATION; VITELLOGENIN; WOOD FIBER;

KRAFT PULP;

DISSOLVED OXYGEN; ENDOCRINE DISRUPTOR; RIVER WATER; TESTOSTERONE; VITELLOGENIN; WATER; INDUSTRIAL WASTE; SEX HORMONE; WATER POLLUTANT;

CYPRINID; DISSOLVED OXYGEN; EFFLUENT; ENDOCRINE DISRUPTOR; HYPOXIA; MESOCOSM; PERCIFORM; PULP AND PAPER INDUSTRY; SEX HORMONE; WASTEWATER;

ANIMAL TISSUE; ARTICLE; BLEACHING; CANADA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DROUGHT; EFFLUENT; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; FEMALE; FIELD EXPERIMENT; FISH; FLOW RATE; GONAD; HERMAPHRODITISM; HORMONE DETERMINATION; HYPOXIA; LIFE CYCLE; MALE; MESOCOSM; NONHUMAN; PAPER INDUSTRY; PIMEPHALES PROMELAS; PRIORITY JOURNAL; PULP MILL; REPRODUCTIVE TOXICITY; RIVER; SEDIMENTATION; WASTE WATER MANAGEMENT; ANIMAL; ANOXIA; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; COMPLICATION; DISORDER OF SEX DEVELOPMENT; DRUG EFFECTS; FISH DISEASE; INDUSTRIAL WASTE; PAPER; REPRODUCTION; SPECIES DIFFERENCE; TOXICITY; VETERINARY; WATER POLLUTANT;

DISSOLVED OXYGEN; DISSOLVING; EFFLUENTS; FISHES; KRAFT PULPS; MEAT; PAPER MILLS; PULP MILLS; RIVERS; SURVEYS; WASTE WATERS;

CANADA; ONTARIO [CANADA]; WABIGOON RIVER;

PIMEPHALES PROMELAS; SANDER VITREUS; STIZOSTEDION VITREUM;

ANIMALS; ANOXIA; DISORDERS OF SEX DEVELOPMENT; ENDOCRINE DISRUPTORS; FEMALE; FISH DISEASES; FISHES; GONADAL STEROID HORMONES; INDUSTRIAL WASTE; MALE; PAPER; REPRODUCTION; RIVERS; SPECIES SPECIFICITY; WATER POLLUTANTS, CHEMICAL;

EID: 77951058630     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.118     Document Type: Article

References (39)

1. Stanko JP, Angus RA. 2005. Paper manufacture and its impact on the aquatic environment. Rev Environ Contam Toxicol 185:67-92.
2. Dubé MG, MacLatchy DL. 2000. Endocrine responses of Fundulus heteroclitus to effluent from a bleached-kraft pulp mill before and after installation of reverse osmosis treatment of a waste stream. Environ Toxicol Chem 19:2788-2796.
3. Dubé MG, MacLatchy DL. 2001. Identification and treatment of a waste stream at a bleached-kraft pulp mill that depresses a sex steroid in the mummichog (Fundulus heteroclitus). Environ Toxicol 20:985-995.
4. Kovacs T, Martel P, Ricci M, Michaud J, Voss R. 2005. Further insights into the potential of pulp and paper mill effluents to affect fish reproduction. J Toxicol Environ Health A 68:1621-1641. (Pubitemid 41783267)
5. Rickwood CJ, Dubé MG, Hewitt ML, Kovacs TG, Parrott JL, MacLatchy DL. 2006. Use of paired fathead minnow (Pimephales promelas) reproductive test. Part 1: Assessing biological effects of final bleached kraft pulp mill effluent using a mobile bioassay trailer system. Environ Toxicol Chem 25:1836-1846.
6. Rickwood CJ, Dubé MG, Hewitt LM, Kovacs TG, MacLatchy DL. 2006b. Use of paired fathead minnow (Pimephales promelas) reproductive test. Part 2: Source identification of biological effects at a bleached kraft pulp mill. Environ Toxicol Chem 25:1847-1856.
7. Belknap AM, Solomon KR, MacLatchy DL, Dubé MG, Hewitt LM. 2006. Identification of compounds associated with testosterone depressions in fish exposed to bleached kraft pulp and paper mill chemical recovery condensates. Environ Toxicol Chem 25:2322-2333.
8. Munkittrick KR, McGeachy SA, McMaster ME, Courtenay SC. 2002. Overview of freshwater fish studies from the pulp and paper environmental effects monitoring program. Water Qual Res J Can 37:49-77. (Pubitemid 34246780)
9. Lowell RB, Ring B, Pastershank G, Walker S, Trudel L, Hedley K. 2005. National assessment of pulp and paper environmental effects monitoring data: Findings from cycles 1 through 3. NWRI Scientific Assessment Report Series 5. National Water Research Institute, Burlington, ON, Canada, p 40.
10. Lister A, Van Der Kraak G. 2001. Endocrine disruption: Why is it so complicated? Water Qual Res J Can 36:175-190.
11. Jobling S, Tyler CR. 2003. Endocrine disruption, parasites and pollutants in wild freshwater fish. Parasitology 126:103-108. (Pubitemid 37485401)
12. Orrego R, Burgos A, Moraga-Cid G, Inzunza B, Gonzalez M, Valenzuela A, Barra R, Gavilan JE. 2006. Effects of pulp and paper mill discharges on caged rainbow trout (Oncorhynchus mykiss): Biomarker responses along a pollution gradient in the Biobio River, Chile. Environ Toxicol Chem 25:2280-2287. (Pubitemid 44763283)
13. Sepúlveda MS, Quinn BP, Denslow ND, Holm SE, Gross TS. 2003. Effects of pulp and paper mill effluents on reproductive success of largemouth bass. Environ Toxicol Chem 22:205-213.
14. Örn S, Svenson A, Viktor T, Holbech H, Norrgren L. 2006. Male-biased sex ratios and vitellogenin induction in zebrafish exposed to effluent water from a Swedish pulp mill. Arch Environ Contam Toxicol 51:445-451. (Pubitemid 44310398)
15. Larsson DGJ, Hallman H, Forlin L. 2000. More male fish embryos near a pulp mill. Environ Toxicol Chem 19:2911-2917. (Pubitemid 32113299)
16. Golder Associates. 2007. Environmental effects Monitoring for Cycle 4. Final Interpretative Report. Weyerhaeuser Canada, Dryden, ON.
17. Environment Canada. 1998. Effects on fish and fisheries resources: fish survey, tissue analyses and tainting evaluations. Pulp and Paper Technical Guidance for Aquatic Environmental Effects Monitoring. EEM/199/1. Gatineau, Quebec pp. 5-1-5-86.
18. Schryer RP. 1994. The reproductive successes of the walleye (Stizostedion vitreum) in both saline and non-saline environments. PhD thesis. University of Saskatchewan, Saskatoon, SK, Canada.
19. Ankley G, Jensen KM, Kahl MD, Korte JJ, Makynen EA. 2001. Description and evaluation of short-term reproduction test with the fathead minnow (Pimephales promelas). Environ Toxicol Chem 20:1276-1290. (Pubitemid 32861480)
20. Rickwood CJ, Dubé MG. 2007. Application of a pair-breeding fathead minnow (Pimephales promelas) adult reproduction bioassay to a pulp mill effluent. Water Qual Res J Can 42:82-90.
21. Rickwood CJ, Dubé MG, Weber LP, Driedger KL, Janz DM. 2006. Assessing effects of metal mining effluent on fathead minnow (Pimephales promelas) reproduction in a trophic-transfer exposure system. Environ Sci Technol 40:6489-6497.
22. Organization for Economic Co-operation and Development. 2003. Draft detailed review paper on fish two-generation and proposal for a fish two-generation test guideline. DRP Draft Guideline, Paris, France.
23. Weber LP, Hill RL Jr, Janz DM. 2002. Developmental estrogenic exposure in zebrafish (Danio rerio). II. Histological evaluation of gametogenesis and organ toxicity. Aquat Toxicol 63:431-446.
24. Siegel S, Castellan NJ Jr. 1988. Nonparametric Statistics for the Behavioural Sciences. 2nd ed. McGraw-Hill, New York, NY, USA.
25. Hewitt M, Schryer R, Pryce A, Belknap A, Firth B, Van Der Kraak G. 2005. Accumulation of hormonally active substances by wild white sucker (Catostomus commersoni) exposed to effluents discharged to the Wabigoon River. Water Qual Res J Can 40:315-327. (Pubitemid 41724180)
26. Dedual M. 2003. Record of a wild intersexual rainbow trout (Oncorhynchus mykiss) in Taupo, New Zealand. NZ J Mar Freshw Res 37:521-523. (Pubitemid 38062142)
27. BEAK. 2000. Second Cycle EEM Final Interpretative Report. Weyerhaeuser Canada, Dryden, ON.
28. Golder Associates. 2002. Fall 2000 Wabigoon River fish health assessment report. Weyerhaeuser Canada, Dryden, ON.
29. Gibbons WN, Munkittrick KR, McMaster ME, Taylor WD. 1998. Monitoring aquatic environments receiving industrial effluents using small fish species 2: Comparison between responses of trout-perch (Percopsis omiscomaycus) and white sucker (Catostomus commersoni) downstream of a pulp mill. Environ Toxicol Chem 17:2238-2245. (Pubitemid 28483956)
30. Ankley GT, Johnson RD. 2004. Small fish models for identifying and assessing the effects of endocrine-disrupting chemicals. ILAR J 45:469-483.
31. Golder Associates. 2000. Grande Prairie Environmental Effects Monitoring for Cycle 2 Final Interpretative Report. Weyerhaeuser Canada, Dryden, ON.
32. Folmar LC, Denslow ND, Kroll K, Orlando EF, Enblom J, Marcino J, Metcalfe C, Guillette LJ. 2001. Altered serum sex steroids and vitellogenin induction in walleye (Stizostedion vitreum) collected near a metropolitan sewage treatment plant. Arch Environ Contam Toxicol 40:392-398. (Pubitemid 32488560)
33. Jobling S, Nolan M, Tyler CR, Brighty G, Sumpter JP. 1998. Widespread sexual disruption in wild fish. Environ Sci Technol 32:2498-2506. (Pubitemid 28420276)
34. Jobling S, Coey S, Whitmore JG, Kime DE, Van Look KJW, McAllister BG, Beresford N, Henshaw AC, Brighty G, Tyler CR, Sumpter JP. 2002. Wild intersex roach (Rutilus rutilus) have reduced fertility. Biol Reprod 67:515-524. (Pubitemid 34803938)
35. Goldberg ED. 1995. Emerging problems in the coastal zone for the twenty-first century. Mar Pollut Bull 31:152-158.
36. Diaz RJ. 2001. Overview of hypoxia around the world. J Environ Qual 30:275-281.
37. Wu RSS, Zhou BS, Randall DJ, Woo NYS, Lam PKS. 2003. Aquatic hypoxia is an endocrine disruptor and impairs fish reproduction. Environ Sci Technol 37:1137-1141.
38. Thomas P, Rahman MS, Kummer JA, Lawson S. 2006. Reproductive endocrine dysfunction in Atlantic croaker exposed to hypoxia. Mar Environ Res 62:249-252. (Pubitemid 43867742)
39. Pollock MS, Clarke LMJ, Dubé MG. 2007. The effects of hypoxia on fishes: from ecological relevance to physiological effects. Environ Rev 15:1-14.