Problems meeting basic needs moderate the association between the APOE ε4 allele and cognitive decline

Aging and Mental Health

Volumn 14, Issue 2, 2010, Pages 138-144

  Sachs Ericsson, Natalie ^a   Corsentino, Elizabeth ^a   Collins, Nicole ^a   Sawyer, Kathryn ^a   Blazer, Dan G ^b  

^a FLORIDA STATE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

APOE 4 allele; Basic needs; Cognitive decline

Indexed keywords

APOLIPOPROTEIN E4;

AGED; AGING; ALLELE; ARTICLE; COGNITIVE DEFECT; DAILY LIFE ACTIVITY; EDUCATIONAL STATUS; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; INCOME; INFORMATION PROCESSING; MALE; MENTAL HEALTH; NEEDS ASSESSMENT; NEUROPSYCHOLOGICAL TEST; REGRESSION ANALYSIS; RISK FACTOR; UNITED STATES;

ACTIVITIES OF DAILY LIVING; AGED; AGED, 80 AND OVER; AGING; ALLELES; APOLIPOPROTEIN E4; COGNITION DISORDERS; DATA COLLECTION; EDUCATIONAL STATUS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INCOME; MALE; MENTAL STATUS SCHEDULE; NEEDS ASSESSMENT; NEUROPSYCHOLOGICAL TESTS; NORTH CAROLINA; REGRESSION ANALYSIS; RISK FACTORS;

EID: 77951039101     PISSN: 13607863     EISSN: 13646915     Source Type: Journal    
DOI: 10.1080/13607860903421060     Document Type: Article

References (32)

1. Anttila, T., Helkala, E.L., Kivipelto, M., Hallikainen, M., Alhainen, K., Heinonen, H., et al. (2002). Midlife income, occupation, APOE status, and dementia: A populationbased study. Neurology, 59(6), 887-893.
2. Black, S.A., Markides, K.S., & Miller, T.Q. (1998). Correlates of depressive symptomatology among older community-dwelling Mexican Americans: The Hispanic EPESE. Journals of Gerontology Series B Psychological Sciences and Social Sciences, 53(4), S198-S208.
3. Blazer, D.G., Sachs-Ericsson, N., & Hybels, C.F. (2005). Perception of unmet basic needs as a predictor of mortality among community-dwelling older adults. American Journal of Public Health, 95(2), 299-304.
4. Bretsky, P., Guralnik, J.M., Launer, L., Albert, M., & Seeman, T.E. (2003). The role of APOE-{epsilon}4 in longitudinal cognitive decline: MacArthur studies of successful aging. Neurology, 60(7), 1077-1081.
5. Corder, E., Lannfelt, L., & Vitanen, M. (1996). Apolipoprotein E genotypes determines survival in the oldest old (85 years or older) who have good cognition. Archives of Neurology, 53, 418-422.
6. Cornoni-Huntley, J., Blazer, D., Lafferty, M., Everett, D., Brock, D., & Farmer, M. (Eds.) (1990). Established populations for epidemiologic studies of the elderly: Resource Data Book. Bethesda, MD: National Institute on Aging.
7. Ferraro, K.F., & Su, Y. (1999). Financial strain, social relations, and psychological distress among older people: A cross-cultural analysis. Journals of Gerontology Series B Psychological Sciences and Social Sciences, 54(1), S3-S15.
8. Fillenbaum, G., Landerman, R., Blazer, D., Saunders, A., Harris, T., & Launer, L. (2001). The relationship of APOE genotype to cognitive functioning in African American and White community resident elderly. Journal of the American Geriatrics Society, 49(9), 1148-1155.
9. Francoeur, R.B. (2002). Use of an income-equivalence scale to understand age-related changes in financial strain. Research on Aging, 24(4), 445-472.
10. George, L.K. (2005). Socioeconomic status and health across the life course: Progress and prospects. Journals of Gerontology Series B Psychological Sciences and Social Sciences, 60(Suppl. Special Issue 2), S135-S139.
11. Geronimus, A.T. (1996). Black/White differences in the relationship of maternal age to birthweight: A population-based test of the weathering hypothesis. Social Science & Medicine, 42(4), 589-597.
12. Geronimus, A.T. (2001). Understanding and eliminating racial inequalities in women's health in the United States: The role of the weathering conceptual framework. Journal of the American Medical Women's Association, 56(4), 1-5.
13. Geronimus, A.T., Hicken, M., Keene, D., & Bound, J. (2006). 'Weathering' and age patterns of allostatic load scores among blacks and whites in the United States. American Journal of Public Health, 96(5), 826-833.
14. Grundy, E., & Holt, G. (2001). The socioeconomic status of older adults: How should we measure it in studies of health inequalities? Journal of Epidemiology and Community Health, 55(12), 895-904.
15. Harwood, R., Prince, M., Mann, A., & Ebrahim, S. (1998). Associations between diagnoses, impairments, disability and handicap in a population of elderly people. International Journal of Epidemiology, 27(2), 261-268.
16. Mahley, R.W., Weisgraber, K.H., & Huang, Y. (2006). Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease. The National Academy of Sciences of the USA, 103(15), 5644-5651.
17. Martins, C.A.R., Oulhaj, A., de Jager, C.A., & Williams, J.H. (2005). APOE alleles predict the rate of cognitive decline in Alzheimer disease: A nonlinear model. Neurology, 65(12), 1888-1893.
18. Mayeux, R., Small, S.A., Tang, M., Tycko, B., & Stern, Y. (2001). Memory performance in healthy elderly without Alzheimer's disease: Effects of time and Apolipoprotein-E. Neurobiology of Aging, 22(4), 683-689.
19. Pfeiffer, E. (1975). A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. Journal of the American Geriatrics Society, 23, 433-441.
20. Qiu, C., Kivipelto, M., Aguero-Torres, H., Winblad, B., & Fratiglioni, L. (2004). Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: Variation by age and sex. Journal of Neurology, Neurosurgery & Psychiatry, 75(6), 828-833.
21. Radloff, L. (1977). The CES-D Scale: A self-report depression scale for research in the general population. Applied Psychological Measures, 1, 385-401.
22. Rosow, I., & Breslau, N.A. (1996). Guttman health scale for the aged. Journal of Gerontology, 21, 556-559.
23. Sachs-Ericsson, N., Plant, E.A., & Blazer, D.G. (2005). Racial differences in the frequency of depressive symptoms among community dwelling elders: The role of social economic factors. Aging and Mental Health, 9(3), 201-209.
24. Sachs-Ericsson, N., Schatschneider, C., & Blazer, D.G. (2006). Perception of unmet basic needs as a predictor of physical functioning among community-dwelling older adults. Journal of Aging and Health, 18(6), 852-868.
25. Sapolsky, R.M. (1996). Why stress is bad for your brain. Science, 273(5276), 749-750.
26. Sawyer, K., Sachs-Ericsson, N., Preacher, K.J., & Blazer, D.G. (in press). Racial differences in the influence of the APOE epsilon 4 allele on cognitive decline in a sample of community-dwelling older adults. Gerontology, 55(1), 32-40.
27. Shadlen, M.F., Larson, E.B., Wang, L., Phelan, E.A., McCormick, W.C., Jolley, L., et al. (2005). Education modifies the effect of Apolipoprotein epsilon 4 on cognitive decline. Neurobiology of Aging, 26(1), 17-24.
28. Smith, M.A., Makino, S., Kvetnansky, R., & Post, R.M. (1995). Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. Journal of Neuroscience, 15(3), 1768-1777.
29. Stern, Y. (2003). The concept of cognitive reserve: A catalyst for research. Journal of Clinical and Experimental Neuropsychology, 25(5), 589-593.
30. Tung, H.-J., & Mutran, E.J. (2005). Ethnicity and health disparities among the elderly in Taiwan. Research on Aging, 27(3), 327-354.
31. van Lenthe, F.J., Schrijvers, C.T.M., Droomers, M., Joung, I.M.A., Louwman, M.J., & Mackenbach, J.P. (2004). Investigating explanations of socio-economic inequalities in health: The Dutch GLOBE study. European Journal of Public Health, 14(1), 63-70.
32. Zhang, Z., Gu, D., & Hayward, M.D. (2008). Early life influences on cognitive impairment among oldest old Chinese. Journals of Gerontology Series B Psychological Sciences and Social Sciences, 63(1), S25-S33.