Dendritic cells are susceptible to infection with wild-type adenovirus, inducing a differentiation arrest in precursor cells and inducing a strong T-cell stimulation

Journal of General Virology

Volumn 91, Issue 5, 2010, Pages 1150-1154

  Keßler, Tobias ^a   Hamprecht, Klaus ^a   Feuchtinger, Tobias ^b   Jahn, Gerhard ^a  

^a Institut fur Medizinische Virologie   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIGEN;

ADENOVIRUS INFECTION; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL LINEAGE; CELL STIMULATION; CONTROLLED STUDY; DENDRITIC CELL; HUMAN ADENOVIRUS; IMMUNE RESPONSE; INFECTION SENSITIVITY; MOLECULAR RECOGNITION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; STEM CELL; VIRUS STRAIN; WILD TYPE;

ADENOVIRIDAE INFECTIONS; ADENOVIRUSES, HUMAN; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CHILD, PRESCHOOL; DENDRITIC CELLS; HUMANS; MONOCYTES;

ADENOVIRIDAE; HUMAN ADENOVIRUS;

EID: 77951028449     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.013920-0     Document Type: Article

References (17)

1. Adams, W. C., Bond, E., Havenga, M. J., Holterman, L., Goudsmit, J., Karlsson-Hedestam, G. B., Koup, R. A. & Lore, K. (2009). Adenovirus serotype 5 infects human dendritic cells via a CAR-independent receptor pathway mediated by lactoferrin and DC-SIGN. J Gen Virol 90, 1600-1610.
2. Beck, K., Meyer-Konig, U., Weidmann, M., Nern, C. & Hufert, F. T. (2003). Human cytomegalovirus impairs dendritic cell function: a novel mechanism of human cytomegalovirus immune escape. Eur J Immunol 33, 1528-1538. (Pubitemid 36790413)
3. Feuchtinger, T., Lang, P. & Handgretinger, R. (2007). Adenovirus infection after allogeneic stem cell transplantation. Leuk Lymphoma 48, 244-255. (Pubitemid 46994874)
4. Feuchtinger, T., Richard, C., Joachim, S., Scheible, M. H., Schumm, M., Hamprecht, K., Martin, D., Jahn, G., Handgretinger, R. & Lang, P. (2008). Clinical grade generation of hexon-specific T cells for adoptive T-cell transfer as a treatment of adenovirus infection after allogeneic stem cell transplantation. J Immunother 31, 199-206.
5. Grigoleit, U., Riegler, S., Einsele, H., Laib Sampaio, K., Jahn, G., Hebart, H., Brossart, P., Frank, F. & Sinzger, C. (2002). Human cytomegalovirus induces a direct inhibitory effect on antigen presentation by monocyte-derived immature dendritic cells. Br J Haematol 119, 189-198. (Pubitemid 35176520)
6. Howard, D. S., Phillips, I. G., Reece, D. E., Munn, R. K., Henslee-Downey, J., Pittard, M., Barker, M. & Pomeroy, C. (1999). Adenovirus infections in hematopoietic stem cell transplant recipients. Clin Infect Dis 29, 1494-1501. (Pubitemid 30022747)
7. Jahn, G., Stenglein, S., Riegler, S., Einsele, H. & Sinzger, C. (1999). Human cytomegalovirus infection of immature dendritic cells and macrophages. Intervirology 42, 365-372. (Pubitemid 30122072)
8. Kessler, T., Reich, M., Jahn, G., Tolosa, E., Beck, A., Kalbacher, H., Overkleeft, H., Schempp, S. & Driessen, C. (2008). Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels. J Gen Virol 89, 2427-2436.
9. La Rosa, A. M., Champlin, R. E., Mirza, N., Gajewski, J., Giralt, S., Rolston, K. V., Raad, I., Jacobson, K., Kontoyiannis, D. & other authors (2001). Adenovirus infections in adult recipients of blood and marrow transplants. Clin Infect Dis 32, 871-876. (Pubitemid 32524820)
10. Moutaftsi, M., Brennan, P., Spector, S. A. & Tabi, Z. (2004). Impaired lymphoid chemokine-mediated migration due to a block on the chemokine receptor switch in human cytomegalovirus-infected dendritic cells. J Virol 78, 3046-3054. (Pubitemid 38314362)
11. Raftery, M. J., Schwab, M., Eibert, S. M., Samstag, Y., Walczak, H. & Schonrich, G. (2001). Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy. Immunity 15, 997-1009. (Pubitemid 34075379)
12. Raftery, M. J., Moncke-Buchner, E., Matsumura, H., Giese, T., Winkelmann, A., Reuter, M., Terauchi, R., Schonrich, G. & Kruger, D. H. (2009). Unravelling the interaction of HCMV with dendritic cells using SuperSAGE. J Gen Virol 90, 2221-2233.
13. Riegler, S., Hebart, H., Einsele, H., Brossart, P., Jahn, G. & Sinzger, C. (2000). Monocyte-derived dendritic cells are permissive to the complete replicative cycle of human cytomegalovirus. J Gen Virol 81, 393-399. (Pubitemid 30077282)
14. Samulski, R. J., Chang, L. S. & Shenk, T. (1987). A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol 61, 3096-3101.
15. Schneider, K., Meyer-Koenig, U. & Hufert, F. T. (2008). Human cytomegalovirus impairs the function of plasmacytoid dendritic cells in lymphoid organs. PLoS One 3, e3482.
16. + T cells. Nat Med 5, 1039-1043.
17. van Tol, M. J., Claas, E. C., Heemskerk, B., Veltrop-Duits, L. A., de Brouwer, C. S., van Vreeswijk, T., Sombroek, C. C., Kroes, A. C., Beersma, M. F. & other authors (2005). Adenovirus infection in children after allogeneic stem cell transplantation: diagnosis, treatment and immunity. Bone Marrow Transplant 35 (Suppl. 1), S73-S76. (Pubitemid 40613928)