Remote Thermal Injury Increases LPS-Induced Intestinal IL-6 Production1

Journal of Surgical Research

Volumn 160, Issue 2, 2010, Pages 190-195

  Huber, Nathan L ^a   Bailey, Stephanie R ^a   Schuster, Rebecca M ^a   Ogle, Cora K ^a   Lentsch, Alex B ^a   Pritts, Timothy A ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

AP 1; burn; IL 6; intestinal mucosa; TLR 4

Indexed keywords

INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOPEROXIDASE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; INFLAMMATION; INTESTINE MUCOSA; JEJUNUM MUCOSA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REMOTE THERMAL INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCALD; SHAM PROCEDURE; THERMAL INJURY; WESTERN BLOTTING;

ANIMALS; BURNS; CCAAT-ENHANCER-BINDING PROTEINS; COLON; INFLAMMATION; INTERLEUKIN-6; INTESTINAL MUCOSA; JEJUNUM; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 77951023754     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.06.006     Document Type: Article

References (21)

1. Baue A.E., Durham R., and Faist E. Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): Are we winning the battle?. Shock 10 (1998) 79
2. Harris B.H., and Gelfand J.A. The immune response to trauma. Semin Pediatr Surg 4 (1995) 77
3. Saffle J.R., Sullivan J.J., Tuohig G.M., et al. Multiple organ failure in patients with thermal injury. Crit Care Med 21 (1993) 1673
4. Sanucci S.G., Gobara S., Santos C.R., et al. Infections in a burn intensive care unit: Experience of 7 years. J Hosp Infect 53 (2003) 6
5. Moore F.A., and Moore E.E. Evolving concepts in the pathogenesis of multiple organ failure. Surg Clin North Am 75 (1995) 257
6. Rue III L.W., Cioffi W.G., Mason A.D., et al. The risk of pneumonia in thermally injured patients requiring ventilatory support. J Burn care Rehabilitation 16 (1995) 262
7. Geyik M.F., Aldemir M., Hosoblu S., et al. Epidemiology of burn unit infections in children. Am J Infect Control 31 (2003) 342
8. Wang Z., Xiao G., Yao Y., et al. The role of bifidobacteria in gut barrier function after thermal injury in rats. J Trauma 61 (2006) 650
9. Wang Z, Xiao G, Yao Y, et al. The relationship between intestinal bifidobacteria and bacteria/endotoxin translocation in scalded rats. Zhonghua Shao Shang Za Zhi 2002;18:365.
10. Bai X, Xiao G,Tian X, The relationship between postburn gene expression of modulators in gut associated lymph tissue and the change in IgA plasma cells Zhonghua Shao Shang Za Zhi 2000;16:108.
11. Ogle C.K., Mao J.X., Wu J.Z., et al. The 1994 Lindberg Award: The production of tumor necrosis factor, interleukin-1, interleukin-6, and prostaglandin E2 by isolated enterocytes and gut macrophages: Effect of lipopolysaccharide and thermal injury. J Burn Care Rehab 15 (1994) 470
12. Noel J.G., Guo X., Wells-Byrum D., et al. Effect of thermal injury on splenic myelopoiesis. Shock 23 (2005) 115
13. Pritts T.A., Wang Q., Sun X., et al. Induction of the stress response in vivo decreases nuclear factor-κB activity in jejunal mucosa of endotoxemic. Mice Arch Surg 135 (2000) 860
14. Tung P.H., Wang Q., Ogle C.K., et al. Minimal increase in gut-mucosal interleukin-6 during laparoscopy. Surg Endosc 12 (1998) 409
15. Schierwagen C., Bylund-Fellenius A.C., and Lundberg C. Improved method for quatification of tissue PMN accumulation measured by myeloperoxidase activity. J Pharmacol Methods 23 (1990) 179
16. Matsusaka T., Fujikawa K., Nishio Y., et al. Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6, and interleukin 8. PNAS 90 (1993) 10193
17. Dendorfer U., Oettgen P., and Libermann T.A. Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide. Mol Cell Biol 14 (1994) 4443
18. Faith M., Sukumaran A., Pulimood A.B., et al. How reliable an indicator of inflammation is myeloperoxidase activity?. Clin Chim Acta 396 (2008) 39623
19. Yang R., Han X., Uchiyama T., et al. IL-6 is essential for development of gut barrier dysfunction after hemorrhagic shock and resuscitation in mice. Am J Physiol Gastrointest Liver Physiol 285 (2003) 621
20. Cairns B.A., Barnes C.M., Mlot S., et al. Toll-like receptor 2 and 4 ligation results in complex altered cytokine profiles early and late after burn injury. J Trauma 64 (2008) 1069
21. Avalan D., Taskinlar H., Tamer L., et al. Protective effect of trapidil against oxidative organ damage in burn injury. Burns 31 (2005) 859