Calcitonin gene-related peptide immunoreactive neurons innervating the soft palate, the root of tongue, and the pharynx in the superior glossopharyngeal ganglion of the rat

Journal of Chemical Neuroanatomy

Volumn 39, Issue 4, 2010, Pages 221-227

  Hayakawa, T ^a   Kuwahara, Sachi ^a   Maeda, Seishi ^a   Tanaka, Koichi ^a   Seki, Makoto ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Cranial ganglia; Glossopharyngeal nerve; Immunohistochemistry; Nociceptive neurons; Oral pharyngeal region; Retrograde tracing

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; FLUOROGOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL LABELING; CELLULAR DISTRIBUTION; GLOSSOPHARYNGEAL NERVE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MEDULLA OBLONGATA; NERVE CELL; NOCICEPTION; NODOSE GANGLION; NONHUMAN; PHARYNX; PRIORITY JOURNAL; RAT; SENSORY NERVE; SOFT PALATE; SOLITARY TRACT NUCLEUS; TONGUE;

AFFERENT PATHWAYS; ANIMALS; BIOLOGICAL MARKERS; CALCITONIN GENE-RELATED PEPTIDE; FLUORESCENT ANTIBODY TECHNIQUE; GANGLIA, SENSORY; GLOSSOPHARYNGEAL NERVE; IMMUNOHISTOCHEMISTRY; MALE; MOUTH; NEURONAL TRACT-TRACERS; NOCICEPTORS; PAIN; PALATE, SOFT; PHARYNX; RATS; RATS, SPRAGUE-DAWLEY; SENSORY RECEPTOR CELLS; SOLITARY NUCLEUS; STILBAMIDINES; TONGUE;

EID: 77951023236     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchemneu.2009.12.003     Document Type: Article

References (41)

1. Altschuler S.M., Bao X., Bieger D., Hopkins D.A., Miselis R.R. Viscerotopic representation of the upper alimentary tract in the rat: sensory ganglia and nuclei of the solitary and spinal trigeminal tracts. J. Comp. Neurol. 1989, 283(2):248-268.
2. Bao X., Wiedner E.B., Altschuler S.M. Transsynaptic localization of pharyngeal premotor neurons in rat. Brain Res. 1995, 696(1-2):246-249.
3. Batten T.F., Lo V.K., Maqbool A., McWilliam P.N. Distribution of calcitonin gene-related peptide-like immunoreactivity in the medulla oblongata of the cat, in relation to choline acetyltransferase-immunoreactive motoneurones and substance P-immunoreactive fibres. J. Chem. Neuroanat. 1989, 2(3):163-176.
4. Bieger D., Hopkins D.A. Viscerotopic representation of the upper alimentary tract in the medulla oblongata in the rat: the nucleus ambiguus. J. Comp. Neurol. 1987, 262(4):546-562.
5. Brining S.K., Smith D.V. Distribution and synaptology of glossopharyngeal afferent nerve terminals in the nucleus of the solitary tract of the hamster. J. Comp. Neurol. 1996, 365(4):556-574.
6. Calupca M.A., Vizzard M.A., Parsons R.L. Origin of pituitary adenylate cyclase-activating polypeptide (PACAP)-immunoreactive fibers innervating guinea pig parasympathetic cardiac ganglia. J. Comp. Neurol. 2000, 423(1):26-39.
7. Contreras R.J., Beckestead R.M., Norgren R. The central projections of the trigeminal, facial, glossopharyngeal and vagus nerves: an autoradiographic study in the rat. J. Auton. Nerv. Syst. 1982, 6(3):303-322.
8. Folan-Curran J., Hickey K., Monkhouse W.S. Innervation of the rat external auditory meatus: a retrograde tracing study. Somatosens. Mot. Res. 1994, 11(1):65-68.
9. Fried K., Arvidsson J., Robertson B., Brodin E., Theodorsson E. Combined retrograde tracing and enzyme/immunohistochemistry of trigeminal ganglion cell bodies innervating tooth pulps in the rat. Neuroscience 1989, 33(1):101-109.
10. Gabella G. The vagus nerve. Structure of the Autonomic Nervous System 1976, Halsted Press, New York, pp. 133-145.
11. Gaspersic R., Kovacic U., Cor A., Skaleric U. Identification and neuropeptide content of trigeminal neurons innervating the rat gingivomucosal tissue. Arch. Oral Biol. 2006, 51(8):703-709.
12. Gibbins I.L., Furness J.B., Costa M., MacIntyre I., Hillyard C.J., Girgis S. Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of guinea pigs. Neurosci. Lett. 1985, 57(2):125-130.
13. Hamilton R.B., Norgren R. Central projections of gustatory nerves in the rat. J. Comp. Neurol. 1984, 222(4):560-577.
14. Hammond D.L., Ruda M.A. Developmental alterations in nociceptive threshold, immunoreactive calcitonin gene-related peptide and substance P, and fluoride-resistant acid phosphatase in neonatally capsaicin-treated rats. J. Comp. Neurol. 1991, 312(3):436-450.
15. Hayakawa T., Takanaga A., Maeda S., Seki M., Yajima Y. Subnuclear distribution of afferents from the oral, pharyngeal and laryngeal regions in the nucleus tractus solitarii of the rat: a study using transganglionic transport of cholera toxin. Neurosci. Res. 2001, 39(2):221-232.
16. Hayakawa T., Takanaga A., Tanaka K., Maeda S., Seki M. Ultrastructure of the central subnucleus of the nucleus tractus solitarii and the esophageal afferent terminals in the rat. Anat. Embryol. (Berl.) 2003, 206(4):273-281.
17. Hayakawa T., Yajima Y., Zyo K. Ultrastructural characterization of pharyngeal and esophageal motoneurons in the nucleus ambiguus of the rat. J. Comp. Neurol. 1996, 370(2):135-146.
18. Hayakawa T., Zheng J.Q., Seki M., Yajima Y. Synaptology of the direct projections from the nucleus of the solitary tract to pharyngeal motoneurons in the nucleus ambiguus of the rat. J. Comp. Neurol. 1998, 393(3):391-401.
19. Helke C.J., Hill K.M. Immunohistochemical study of neuropeptides in vagal and glossopharyngeal afferent neurons in the rat. Neuroscience 1988, 26(2):539-551.
20. Helke C.J., Niederer A.J. Studies on the coexistence of substance P with other putative transmitters in the nodose and petrosal ganglia. Synapse 1990, 5(2):144-151.
21. Ichikawa H., Terayama R., Yamaai T., Yan Z., Sugimoto T. Brain-derived neurotrophic factor-immunoreactive neurons in the rat vagal and glossopharyngeal sensory ganglia; co-expression with other neurochemical substances. Brain Res. 2007, 1155:93-99.
22. Kalia M., Sullivan J.M. Brainstem projections of sensory and motor components of the vagus nerve in the rat. J. Comp. Neurol. 1982, 211(3):248-265.
23. Kawai Y., Takami K., Shiosaka S., Emson P.C., Hillyard C.J., Girgis S., MacIntyre I., Tohyama M. Topographic localization of calcitonin gene-related peptide in the rat brain: an immunohistochemical analysis. Neuroscience 1985, 15(3):747-763.
24. Keller J.T., Beduk A., Saunders M.C. Central brainstem projections of the superior vagal ganglion of the cat. Neurosci. Lett. 1987, 75(3):265-270.
25. Kruger L., Sternini C., Brecha N.C., Mantyh P.W. Distribution of calcitonin gene-related peptide immunoreactivity in relation to the rat central somatosensory projection. J. Comp. Neurol. 1988, 273(2):149-162.
26. Kummer W. Retrograde neuronal labelling and double-staining immunohistochemistry of tachykinin- and calcitonin gene-related peptide-immunoreactive pathways in the carotid sinus nerve of the guinea pig. J. Auton. Nerv. Syst. 1988, 23(2):131-141.
27. Lundberg J.M., Franco-Cereceda A., Hua X., HÖkfelt T., Fischer J.A. Co-existence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin. Eur. J. Pharmacol. 1985, 108(3):315-319.
28. May O.L., Hill D.L. Gustatory terminal field organization and developmental plasticity in the nucleus of the solitary tract revealed through triple-fluorescence labeling. J. Comp. Neurol. 2006, 497(4):658-669.
29. Mulderry P.K., Ghatei M.A., Rodrigo J., Allen J.M., Rosenfeld M.G., Polak J.M., Bloom S.R. Calcitonin gene-related peptide in cardiovascular tissues of the rat. Neuroscience 1985, 14(3):947-954.
30. Nakamura A., Hayakawa T., Kuwahara S., Maeda S., Tanaka K., Seki M., Mimura O. Morphological and immunohistochemical characterization of the trigeminal ganglion neurons innervating the cornea and upper eyelid of the rat. J. Chem. Neuroanat. 2007, 34(3-4):95-101.
31. Ootani S., Umezaki T., Shin T., Murata Y. Convergence of afferents from the SLN and GPN in cat medullary swallowing neurons. Brain Res. Bull. 1995, 37(4):397-404.
32. Raab M., Neuhuber W.L. Vesicular glutamate transporter 2 immunoreactivity in putative vagal mechanosensor terminals of mouse and rat esophagus: indication of a local effector function?. Cell Tissue Res. 2003, 312(2):141-148.
33. Rodrigo J., Polak J.M., Terenghi G., Cervantes C., Ghatei M.A., Mulderry P.K., Bloom S.R. Calcitonin gene-related peptide (CGRP)-immunoreactive sensory and motor nerves of the mammalian palate. Histochemistry 1985, 82(1):67-74.
34. Skofitsch G., Jacobowitz D.M. Calcitonin gene-related peptide coexists with substance P in capsaicin sensitive neurons and sensory ganglia of the rat. Peptides 1985, 6(4):747-754.
35. Sugimoto T., Fujiyoshi Y., Xiao C., He Y.F., Ichikawa H. Central projection of calcitonin gene-related peptide (CGRP)- and substance P (SP)-immunoreactive trigeminal primary neurons in the rat. J. Comp. Neurol. 1997, 378(3):425-442.
36. Terenghi G., Polak J.M., Rodrigo J., Mulderry P.K., Bloom S.R. Calcitonin gene-related peptide-immunoreactive nerves in the tongue, epiglottis and pharynx of the rat: occurrence, distribution and origin. Brain Res. 1986, 365(1):1-14.
37. Torrealba F., Claps A. The carotid sinus connections: a WGA-HRP study in the cat. Brain Res. 1988, 455(1):134-143.
38. Travers S.P., Norgren R. Organization of orosensory responses in the nucleus of the solitary tract of rat. J. Neurophysiol. 1995, 73(6):2144-2162.
39. Travers S.P., Pfaffmann C., Norgren R. Convergence of lingual and palatal gustatory neural activity in the nucleus of the solitary tract. Brain Res. 1986, 365(2):305-320.
40. Wank M., Neuhuber W.L. Local differences in vagal afferent innervation of the rat esophagus are reflected by neurochemical differences at the level of the sensory ganglia and by different brainstem projections. J. Comp. Neurol. 2001, 435(1):41-59.
41. Xie Q., Itoh M., Miyamoto K., Li L., Takeuchi Y. Cardiac afferents to the nucleus of the tractus solitarius: a WGA-HRP study in the rat. Ann. Thorac. Cardiovasc. Surg. 1999, 5:370-375.