Esmolol and landiolol, selective β1-adrenoreceptor antagonists, provide neuroprotection against spinal cord ischemia and reperfusion in rats

Anesthesia and Analgesia

Volumn 110, Issue 4, 2010, Pages 1133-1137

  Umehara, Shino ^a   Goyagi, Toru ^a   Nishikawa, Toshiaki ^a   Tobe, Yoshitsugu ^a   Masaki, Yoko ^a  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ESMOLOL; LANDIOLOL; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HISTOPATHOLOGY; MALE; MOTONEURON; MOTOR DYSFUNCTION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD ISCHEMIA;

EID: 77951011129     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3181cdb06b     Document Type: Article

References (17)

1. Ronald AK, Marc ES, David MM. Anesthetic consideration for descending thoracic aortic aneurysm repair. Semin Cardiothorac Vasc Anesth 2007;11:205-223 (Pubitemid 47301103)
2. Tabayashi K. Spinal cord protection during thoracoabdominal aneurysm repair. Surg Today 2005;35:1-6 (Pubitemid 40941122)
3. Standefer M, Little JR. Improved neurological outcome in experimental focal cerebral ischemia treated with propranolol. Neurosurgery 1986;18:136-140 (Pubitemid 16161273)
4. John SM, Okamoto S, Shimazu K, Koto A, Ohuchi T. Cerebral metabolic changes during treatment of subacute cerebral infarction by alpha and beta adrenergic blockade with phenoxybenzamine and propranolol. Stroke 1974;5:180-195
5. Lysko PG, Lysko KA, Yue TL, Webb CL, Gu JL, Feuerstein G. Neuroprotective effect of carvedilol, a new antihypertensive agent, in cultured rat cerebellar neurons and in gerbil global brain ischemia. Stroke 1992;23:1630-1636
6. Savitz SI, Erhardt JA, Anthony JV, Gupta G, Li X, Barone FC, Rosenbaum DM. The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke. J Cereb Blood Flow Metab 2000;20:1197-1204 (Pubitemid 30636755)
7. Ilhan A, Yilmaz HR, Armutcu F, Gurel A, Akyol O. The protective effect of nebivolol on ischemia/reperfusion injury in rabbit spinal cord. Progr Neuropsychopharmacol Biol Psychiatry 2004;28:1153-1160 (Pubitemid 40017632)
8. Sugiyama A, Takahara A, Hashimoto K. Electrophysiologic, cardiohemodynamic and beta-blocking actions of a new ultrashort- acting beta-blocker, ONO-1101, assessed by the in vivo canine model in comparison with esmolol. J Cardiovasc Pharmacol 1999;34:70-77 (Pubitemid 29296139)
9. Iguchi S, Iwamura H, Nishizaki M, Hayashi A, Senouchi K, Kobayashi K, Sakaki K, Hachiya K, Ichioka Y, Kawamura M. Development of a highly cardioselective ultra short-acting beta-blocker, ONO-1101. Chem Pharm Bull (Tokyo) 1992;40:1462-1469
10. Goyagi T, Kimura T, Nishikawa T, Tobe Y, Masaki Y.β-Adrenoreceptor antagonists attenuate brain injury after transient focal ischemia in rats. Anesth Analg 2006; 103:658-663 (Pubitemid 44542920)
11. Taira Y, Marsala M. Effect of proximal arterial perfusion pressure on function, spinal cord blood flow, and histopathologic changes after increasing intervals of aortic occlusion in the rat. Stroke 1996;27:1850-1858 (Pubitemid 26332519)
12. Roth E, Torok B. Effect of the ultrashort-acting beta-blocker Brevibloc on free-radical-mediated injuries during the early reperfusion state. Basic Res Cardiol 1991;86:422-433
13. Roth E, Matos G, Guarunieri C, Papp B, Varga J. Influence of the beta-blocker therapy on neutrophil superoxide generation and platelet aggregation in experimental myocardial ischemia and reflow. Acta Physiol Hung 1995;83:163-170
14. Sakanashi M, Sakanashi M, Sugahara K, Sakanashi S. Effects of landiolol on mechanical and metabolic changes in rat reperfused ischaemic hearts. Clin Exp Pharmacol Physiol 2007;34:55-60 (Pubitemid 46069586)
15. Fiers W, Beyaert R, Declercq W, Vandenabeele P. More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 1999;18:7719-7730 (Pubitemid 30052757)
16. Sutin J, Griffith R. Beta-adrenergic receptor blockade suppresses glial scar formation. Exp Neurol 1993;120:214-222 (Pubitemid 23165016)
17. Quon CY, Stampfli HF. Biochemical properties of blood esmolol esterase. Drug Metab Dispos 1985;13:420-424