Poly(3,4-ethylenedioxythiophene) as a micro-neural interface material for electrostimulation

Frontiers in Neuroengineering

Volumn 2, Issue JUN, 2009, Pages

  Wilks, Seth J ^a   Richardson Burns, Sarah M ^b,c   Hendricks, Jeffrey L ^b,c   Martin, David C ^b,c   Otto, Kevin J ^a,d  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Biotectix LCC   (United States)

^d PURDUE UNIVERSITY   (United States)

Author keywords

Charge injection; Cyclic voltammetry; Impedance; Iridium oxide; Microelectrode

Indexed keywords

EID: 77950990949     PISSN: 16626443     EISSN: None     Source Type: Journal    
DOI: 10.3389/neuro.16.007.2009     Document Type: Article

References (39)

1. Abidian, M. R., Kim, D. H., and Martin, D. C. (2006). Conductingpolymer nanotubes for controlled drug release. Adv. Mater. 18, 405-409.
2. Abidian, M. R., and Martin, D. C. (2008). Experimental and theoretical characterization of implantable neural microelectrodes modified with conducting polymer nanotubes. Biomaterials 29, 1273-1283.
3. Bak, M., Girvin, J. P., Hambrecht, F. T., Kufta, C. V., Loeb, G. E., and Schmidt, E. M. (1990). Visual sensations produced by intracortical microstimulation of the human occipital cortex. Med. Biol. Eng. Comput. 28, 257-259.
4. Bradley, D. C., Troyk, P. R., Berg, J. A., Bak, M., Cogan, S., Erickson, R., Kufta, C., Mascaro, M., McCreery, D., Schmidt, E. M., Towle, V. L., and Xu, H. (2005). Visuotopic mapping through a multichannel stimulating implant in primate V1. J. Neurophysiol. 93, 1659-1670.
5. Brummer, S. B., and Turner, M. J. (1975). Electrical stimulation of the nervous system: the principle of safe charge injection with noble metal electrodes. Bioelectrochem. Bioenerg. 2, 13-25.
6. Butovas, S., and Schwarz, C. (2007). Detection psychophysics of intracortical microstimulation in rat primary somatosensory cortex. Eur. J. Neurosci. 25, 2161-2169.
7. Cogan, S. F. (2008). Neural stimulation and recording electrodes. Annu. Rev. Biomed. Eng. 10, 275-309.
8. Cogan, S. F., Guzelian, A. A., Agnew, W. F., Yuen, T. G., and McCreery, D. B. (2004). Over-pulsing degrades activated iridium oxide films used for intracortical neural stimulation. J. Neurosci. Methods 137, 141-150.
9. Cogan, S. F., Troyk, P. R., Ehrlich, J., and Plante, T. D. (2005). In vitro comparison of the charge-injection limits of activated iridium oxide (AIROF) and platinum-iridium microelectrodes. IEEE Trans. Biomed. Eng. 52, 1612-1614.
10. Cogan, S. F., Troyk, P. R., Ehrlich, J., Plante, T. D., and Detlefsen, D. E. (2006). Potential-biased, asymmetric waveforms for charge-injection with activated iridium oxide (AIROF) neural stimulation electrodes. IEEE Trans. Biomed. Eng. 53, 327-332.
11. Cui, X. T., and Zhou, D. D. (2007). Poly (3,4-ethylenedioxythiophene) for chronic neural stimulation. IEEE Trans. Neural Syst. Rehabil. Eng. 15, 502-508.
12. Cui, X. Y., and Martin, D. C. (2003). Electrochemical deposition and characterization of poly (3,4-ethylenedioxythiophene) on neural microelectrode arrays. Sens. Actuators B Chem. 89, 92-102.
13. Geddes, L. A., and Roeder, R. (2003). Criteria for the selection of materials for implanted electrodes. Ann. Biomed. Eng. 31, 879-890.
14. Ghosh, S., and Inganas, O. (2000). Electrochemical characterization of poly(3,4-ethylene dioxythiophene) based conducting hydrogel networks. J. Electrochem. Soc. 147, 1872-1877.
15. Guimard, N. K., Gomez, N., and Schmidt, C. E. (2007). Conducting polymers in biomedical engineering. Prog. Polym. Sci. 32, 876-921.
16. Kim, D. H., Richardson-Burns, S. M., Hendricks, J. L., Sequera, C., and Martin, D. C. (2007). Effect of immobilized nerve growth factor on conductive polymers: electrical properties and cellular response. Adv. Funct. Mater. 17, 79-86.
17. Kros, A., Sommerdijk, N. A. J. M., and Nolte, R. J. M. (2005). Poly(pyrrole) versus poly(3,4-ethylenedioxythiophene): implications for biosensor applications. Sens. Actuators B Chem. 106, 289-295.
18. Lilly, J. C., Hughes, J. R., Alvord, E. C. Jr., and Galkin, T. W. (1955). Brief, noninjurious electric waveform for stimulation of the brain. Science 121, 468-469.
19. Lim, H. H., and Anderson, D. J. (2006). Auditory cortical responses to electrical stimulation of the inferior colliculus: implications for an auditory midbrain implant. J. Neurophysiol. 96, 975-988.
20. McCreery, D. B. (2008). Cochlear nucleus auditory prostheses. Hear. Res. 242, 64-73.
21. Merrill, D. R., Bikson, M., and Jefferys, J. G. (2005). Electrical stimulation of excitable tissue: design of efficacious and safe protocols. J. Neurosci. Methods 141, 171-198.
22. Mozota, J., and Conway, B. E. (1983). Surface and bulk processes at oxidized iridium electrodes-I. Monolayer stage and transition to reversible multilayer oxide film behaviour. Electrochim. Acta 28, 1-8.
23. Mushahwar, V. K., Gillard, D. M., Gauthier, M. J., and Prochazka, A. (2002). Intraspinal micro stimulation generates locomotor-like and feedback-controlled movements. IEEE Trans. Neural Syst. Rehabil. Eng. 10, 68-81.
24. Normann, R. A., Maynard, E. M., Rousche, P. J., and Warren, D. J. (1999). A neural interface for a cortical vision prosthesis. Vision Res. 39, 2577-2587.
25. Nyberg, T., Shimada, A., and Torimitsu, K. (2007). Ion conducting polymer microelectrodes for interfacing with neural networks. J. Neurosci. Methods 160, 16-25.
26. Otto, K. J., Rousche, P. J., and Kipke, D. R. (2005). Microstimulation in auditory cortex provides a substrate for detailed behaviors. Hear. Res. 210, 112-117.
27. Pikov, V., Bullara, L., and McCreery, D. B. (2007). Intraspinal stimulation for bladder voiding in cats before and after chronic spinal cord injury. J. Neural Eng. 4, 356-368.
28. Richardson-Burns, S. M., Hendricks, J. L., Foster, B., Povlich, L. K., Kim, D. H., and Martin, D. C. (2007a). Polymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) around living neural cells. Biomaterials 28, 1539-1552.
29. Richardson-Burns, S. M., Hendricks, J. L., and Martin, D. C. (2007b). Electrochemical polymerization of conducting polymers in living neural tissue. J. Neural Eng. 4, L6-L13.
30. Robblee, L. S., Lefko, J. L., and Brummer, S. B. (1983). Activated Ir: An electrode suitable for reversible charge injection in saline solution. J. Electrochem. Soc. 130, 731-733.
31. Romo, R., and Salinas, E. (2001). Touch and go: decision-making mechanisms in somatosensation. Annu. Rev. Neurosci. 24, 107-137.
32. Rose, T. L., and Robblee, L. S. (1990). Electrical stimulation with Pt electrodes. VIII. Electrochemically safe charge injection limits with 0.2 ms pulses. IEEE Trans. Biomed. Eng. 37, 1118-1120.
33. Rousche, P. J., and Normann, R. A. (1999). Chronic intracortical microstimulation (ICMS) of cat sensory cortex using the Utah Intracortical Electrode Array. IEEE Trans. Rehabil. Eng. 7, 56-68.
34. Rousche, P. J., Otto, K. J., Reilly, M. P., and Kipke, D. R. (2003). Single electrode micro-stimulation of rat auditory cortex: an evaluation of behavioral performance. Hear. Res. 179, 62-71.
35. Schmidt, E. M., Bak, M. J., Hambrecht, F. T., Kufta, C. V., O'Rourke, D. K., and Vallabhanath, P. (1996). Feasibility of a visual prosthesis for the blind based on intracortical microstimulation of the visual cortex. Brain 119(Pt 2), 507-522.
36. Shannon, R. V. (1992). A model of safe levels for electrical stimulation. IEEE Trans. Biomed. Eng. 39, 424-426.
37. Weiland, J. D., and Anderson, D. J. (2000). Chronic neural stimulation with thinfilm, iridium oxide electrodes. IEEE Trans. Biomed. Eng. 47, 911-918.
38. Weiland, J. D., Anderson, D. J., and Humayun, M. S. (2002). In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes. IEEE Trans. Biomed. Eng. 49, 1574-1579.
39. Weiland, J. D., Liu, W., and Humayun, M. S. (2005). Retinal prosthesis. Annu. Rev. Biomed. Eng. 7, 361-401.