A post-hoc analysis of reduction in diabetic foot ulcer size at 4 weeks as a predictor of healing by 12 weeks

Ostomy Wound Management

Volumn 56, Issue 3, 2010, Pages 44-50

  Snyder, Robert J ^a,b   Cardinal, Matthew ^c   Dauphinée, Damien M ^d   Stavosky, James ^e  

^a University Hospital Tamarac   (United States)

^b TEMPLE UNIVERSITY   (United States)

^c Clinical Research Scientist   (United States)

^d North Texas Hospital   (United States)

^e Seton Medical Center   (United States)

Author keywords

Diabetic foot ulcer; Outcome predictor; Post hoc analysis; Wound assessment; Wound measurement

Indexed keywords

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETIC FOOT; HUMAN; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; WOUND HEALING;

DIABETIC FOOT; HUMANS; WOUND HEALING;

EID: 77950985892     PISSN: 08895899     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Reiber GE, Ledoux WR. Epidemiology of diabetic foot ulcers and amputations. In: Williams R, Herman W, Kinmonth AL, Wareham NJ, eds. The Evidence Base for Diabetes Care. Hoboken, NJ: John Wiley & Sons; 2002:641-665.
2. Boulton AJ, Kirsner RS, Vileikyte L. Clinical practice: neuropathic diabetic foot ulcers. N Engl J Med. 2004;351:48-55. (Pubitemid 39350438)
3. Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet. 2005;366:1719-1724. (Pubitemid 41587452)
4. Sanders LJ. Diabetes mellitus: prevention of amputation. J Am Podiatry Med Assoc. 1994;84:322-328.
5. Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005;293:217-228. (Pubitemid 40095873)
6. Pecoraro RE, Reiber GE, Burgess EM. Pathways to diabetic limb amputation. Basis for prevention. Diabetes Care. 1990;13:513-521.
7. Apelqvist J, Larsson J. What is the most effective way to reduce incidence of amputation in the diabetic foot? Diabetes Metab Res Rev. 2000;16:S75-S83.
8. Ramsey SD, Newton K, Blough D, et al. Incidence, outcomes, and cost of foot ulcers in patients with diabetes. Diabetes Care. 1999;22:382-387. (Pubitemid 29106890)
9. Goodridge D, Trepman E, Sloan J, et al. Quality of life of adults with unhealed and healed diabetic foot ulcers. Foot Ankle Int. 2006;27:274-280.
10. Margolis DJ, Kantor J, Berlin JA. Healing of diabetic neuropathic foot ulcers receiving standard treatment. A meta-analysis. Diabetes Care. 1999;22:692-695. (Pubitemid 29220765)
11. Margolis DJ, Allen-Taylor L, Hoffstad O, Berlin JA. Diabetic neuropathic foot ulcers: predicting which ones will not heal. Am J Med. 2003;115:627-631. (Pubitemid 37505904)
12. Sheehan P, Jones P, Caselli A, Giurini JM, Veves A. Percent change in ulcer area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial. Diabetes Care. 2003;26:1879-1882. (Pubitemid 36929137)
13. Pollak RA, Edington H, Jensen JL, Kroeker RO, Gentzkow GD. A human dermal replacement for the treatment of diabetic foot ulcers. Wounds. 1997;9(1):175-183. (Pubitemid 127580015)
14. Marston WA, Hanft J, Norwood P, Pollack R. The efficacy and safety of Dermagraft in improving the healing of chronic diabetic foot ulcers. Diabetes Care. 2003;26:1701-1705.
15. Zweig M, Campbell G. Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993;39:561-577. (Pubitemid 23118304)
16. American Diabetes Association. Consensus Development Conference on Diabetic Foot Wound Care. Boston, Massachusetts. April 7-8, 1999. Diabetes Care. 1999;22:1354-1360.
17. Margolis DJ, Gelfand JM, Hoffstad O, Berlin JA. Surrogate end points for the treatment of diabetic neuropathic foot ulcers. Diabetes Care. 2003;26:1696-1700. (Pubitemid 36929106)
18. Lavery LA, Barnes SA, Keith MS, Seaman JW, Armstrong DG. Prediction of healing for postoperative diabetic foot wounds based on early wound area progression. Diabetes Care. 2008;31:26-29.
19. Coerper S, Beckert S, Küper MA, Jekov M, Königsrainer A. Fifty percent area reduction after 4 weeks of treatment is a reliable indicator for healing - analysis of a single-center cohort of 704 diabetic patients. J Diabetes Complications. 2009;23:49-53.