Synthesis of novel dendrimers having aspartate grafts and their ability to enhance the aqueous solubility of model drugs

European Journal of Medicinal Chemistry

Volumn 45, Issue 6, 2010, Pages 2705-2711

  Ouyang, Liang ^a   Ma, Lifang ^a   Jiang, Bo ^a   Li, Yanhua ^a   He, Dongsheng ^a   Guo, Li ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Aspartic acid; Dendrimers; L Histidine; Methotrexate; Naproxen; Solubility enhancement

Indexed keywords

ASPARTIC ACID; DENDRIMER; HISTIDINE; METHOTREXATE; NAPROXEN;

AQUEOUS SOLUTION; ARTICLE; DRUG SOLUBILITY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; MASS SPECTROMETER; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PH; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE;

ASPARTIC ACID; DENDRIMERS; DRUG CARRIERS; HISTIDINE; HYDROGEN-ION CONCENTRATION; METHOTREXATE; NAPROXEN; PEPTIDES; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; SURFACE PROPERTIES; TEMPERATURE; WATER;

EID: 77950948560     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.01.069     Document Type: Article

References (34)

1. Lee C.C., MacKay J.A., Frechet J.M.J., and Szoka F.C. Nat. Biotechnol. 23 (2005) 1517-1526
2. Svenson S. Eur. J. Pharm. Biopharm. 71 (2009) 445-462
3. He G., and Guo L. Chin. J. Org. Chem. 28 (2008) 1326-1335
4. Gajbhiye V., Palanirajan V.K., Tekade R.K., and Jain N.K. J. Pharm. Pharmacol. 61 (2009) 983-1003
5. Tekade R.K., Kumar P.V., and Jain N.K. Chem. Rev. 109 (2009) 49-87
6. Esfand R., and Tomalia D.A. Drug Discov. Today 6 (2001) 427-436
7. Svenson S., and Chauhan A.S. Nanomedicine 3 (2008) 679-702
8. Cheng Y.Y., and Xu T.W. Eur. J. Med. Chem. 43 (2008) 2291-2297
9. Jain N.K., and Asthana A. Expert Opin. Drug Deliv. 4 (2007) 495-512
10. Devarakonda B., Hill R.A., and de Villiers M.M. Int. J. Pharm. 284 (2004) 133-140
11. Cheng Y.Y., and Xu T.W. Eur. J. Med. Chem. 40 (2005) 1188-1192
12. Chauhan A.S., Jain N.K., Diwan P.V., and Khopade A.J. J. Drug Target 12 (2004) 575-583
13. Beezer A.E., King A.S.H., Martin I.K., Mitchel J.C., Twyman L.J., and Wain C.F. Tetrahedron 59 (2003) 3873-3880
14. Neofofistou E., and Demadis K.D. Desalination 167 (2004) 257-272
15. Bhadra D., Bhadra S., and Jain N.K. J. Pharm. Pharm. Sci. 8 (2005) 467-482
16. Gupta U., Agashe H.B., and Jain N.K. J. Pharm. Pharm. Sci. 10 (2007) 358-367
17. Namazi H., and Adell M. Biomaterials 26 (2005) 1175-1183
18. Jain N.K., and Gupta U. Expert Opin. Drug Metab. Toxicol. 4 (2008) 1035-1052
19. Gupta U., Agashe H.B., Asthana A., and Jain N.K. Biomacromolecules 7 (2006) 649-658
20. Cheng Y.Y., Xu Z.H., Ma M.L., and Xu T.W. J. Pharm. Sci. 97 (2008) 123-143
21. Prajapati R.N., Tekade R.K., Gupta U., Gajbhiye V., and Jain N.K. Mol. Pharmaceut. 6 (2009) 940-950
22. Ouyang L., Huang W.C., He G., and Guo L. Lett. Org. Chem. 6 (2009) 272-277
23. Ouyang L., Zhang J., Pan J.Z., Yan L.N., and Guo L. Drug Deliv. 16 (2009) 348-356
24. He G., and Guo L. Chin. Chem. Lett. 18 (2007) 1505-1508
25. Choi H.J., Park Y.S., Yun S.H., Kim H.S., Cho C.S., Ko K., and Ahn K.H. Org. Lett. 4 (2002) 795-798
26. Cheng Y.Y., Li M.H., and Xu T.W. Eur. J. Med. Chem. 43 (2008) 1791-1795
27. Curcio M., Parisi O.I., Cirillo G., Spizzirri U.G., Puoci F., Iemma F., and Picci N. e-Polymers (2009) Article number 78
28. Zhang P., and Polavarapu P.L. Appl. Spectrosc. 60 (2006) 378-385
29. Ma M.L., Cheng Y.Y., Xu Z.H., Xu P., Qu H., Fang Y.J., Xu T.W., and Wen L.P. Eur. J. Med. Chem. 42 (2007) 93-98
30. Morgan M.T., Nakanishi Y., Kroll D.J., Griset A.P., Carnahan M.A., Wathier M., Oberlies N.H., Manikumar G., Wani M.C., and Grinstaff M.W. Cancer Res. 66 (2006) 11913-11921
31. Devarakonda B., Otto D.P., Judefeind A.A., Hill R.A., and de Villiers M.M. Int. J. Pharm. 345 (2007) 142-153
32. Doherty B., Rodriguez V., Leslie J.C., McClean S., and Smyth W.F. Rapid Commun. Mass Spectrom. 21 (2007) 2031-2038
33. Smyth W.F., and Rodriguez V. J. Chromatogr., A 1159 (2007) 159-174
34. Felder T., Schalley C.A., Fakhrnabavi H., and Lukin O. Chem. Eur. J. 11 (2005) pp. 5625-2536