Ubiquitin/proteasome-dependent down-regulation following clathrin-mediated internalization of histamine H1-receptors in Chinese hamster ovary cells

Journal of Neurochemistry

Volumn 113, Issue 4, 2010, Pages 990-1001

  Hishinuma, Shigeru ^a   Komazaki, Hiroshi ^a   Fukui, Hiroyuki ^b   Shoji, Masaru ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Clathrin; Down regulation; Histamine H1 receptor; Internalization; Proteasome; Ubiquitin

Indexed keywords

CLATHRIN; HISTAMINE; HISTAMINE H1 RECEPTOR; PROTEASOME; UBIQUITIN;

ANIMAL CELL; ARTICLE; CAVEOLA; CHO CELL; CONTROLLED STUDY; ENDOCYTOSIS; INTERNALIZATION; LIPID RAFT; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RECEPTOR DOWN REGULATION;

ANIMALS; CHLORIDES; CHO CELLS; CLATHRIN; CRICETINAE; CRICETULUS; DOWN-REGULATION; ENDOCYTOSIS; ENZYME INHIBITORS; FILIPIN; G-PROTEIN-COUPLED RECEPTOR KINASE 1; HISTAMINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASE C; PROTEIN TRANSPORT; RECEPTORS, HISTAMINE H1; TRANSPORT VESICLES; UBIQUITIN; ZINC COMPOUNDS;

CRICETULUS GRISEUS;

EID: 77950940974     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06669.x     Document Type: Article

References (58)

1. Aoyagi T., Takeuchi T., Matsuzaki A., Kawamura K., Kondo S., Hamada M., Maeda K. Umezawa H. (1969) Leupeptins, new protease inhibitors from Actinomycetes. J. Antibiot. (Tokyo) 22, 283 286.
2. Bakker R. A., Timmerman H. Leurs R. (2002) Histamine receptors: specific ligands, receptor biochemistry, and signal transduction. Clin. Allergy Immunol. 17, 27 64.
3. Benovic J. L., Strasser R. H., Caron M. G. Lefkowitz R. J. (1986) Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl Acad. Sci. USA 83, 2797 2801.
4. Benovic J. L., Kühn H., Weyand I., Codina J., Caron M. G. Lefkowitz R. J. (1987a) Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). Proc. Natl Acad. Sci. USA 84, 8879 8882.
5. Benovic J. L., Mayor F. Jr., Staniszewski C., Lefkowitz R. J. Caron M. G. (1987b) Purification and characterization of the beta-adrenergic receptor kinase. J. Biol. Chem. 262, 9026 9032.
6. Bonifacino J. S. Weissman A. M. (1998) Ubiquitin and the control of protein fate in the secretory and endocytic pathways. Annu. Rev. Cell. Dev. Biol. 14, 19 57.
7. Claing A., Laporte S. A., Caron M. G. Lefkowitz R. J. (2002) Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Prog. Neurobiol. 66, 61 79.
8. de Duve C., de Barsy T., Poole B., Trouet A., Tulkens P. Van Hoof F. (1974) Lysosomotropic agents. Biochem. Pharmacol. 23, 2495 2531.
9. Ferguson S. S. (2001) Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol. Rev. 53, 1 24.
10. Ferguson S. S., Downey W. E. III., Colapietro A.-M., Barak L. S. Ménard L. (1996) Role of ß-arrestin in mediating agonist promoted G protein-coupled receptor internalization. Science 271, 363 366.
11. Gong Q., Huntsman C. Ma D. (2008) Clathrin-independent internalization and recycling. J. Cell Mol. Med. 12, 126 144.
12. 2-adrenergic receptor. Nature 383, 447 450.
13. Gurevich V. V. Gurevich E. V. (2008) Rich tapestry of G protein-coupled receptor signaling and regulatory mechanisms. Mol. Pharmacol. 74, 312 316.
14. Hamdan F. F., Rochdi M. D., Breton B., Fessart D., Michaud D. E., Charest P. G., Laporte S. A. Bouvier M. (2007) Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2. J. Biol. Chem. 282, 29089 29100.
15. Hanyaloglu A. C. von Zastrow M. (2008) Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu. Rev. Pharmacol. Toxicol. 48, 537 568.
16. Herbert J. M., Augereau J. M., Gleye J. Maffrand J. P. (1990) Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 172, 993 999.
17. Heuser J. E. Anderson R. G. W. (1989) Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J. Cell Biol. 108, 389 400.
18. Hicke L. (2001) A new ticket for entry into budding vesicles-ubiquitin. Cell 106, 527 530.
19. Hill S. J. (1990) Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol. Rev. 42, 45 83.
20. 2+responses in human U373 MG astrocytoma cells. J. Neurochem. 75, 772 781.
21. 1-receptor internalisation, Br. J. Pharmacol. 116, 2715 2723.
22. 1 receptors in human U373 MG astrocytoma cells. J. Neurochem. 71, 2626 2633.
23. 1-receptor antagonists based on receptor internalization. J. Pharmacol. Sci. 107, 66 79.
24. 1 receptors. J. Pharmacol. Sci. 94, 410 419.
25. 1 histamine receptor by G protein-coupled receptor kinase 2. J. Biol. Chem. 280, 2197 2204.
26. 2-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. J. Biol. Chem. 274, 28900 28908.
27. Kohout T. A. Lefkowitz R. J. (2003) Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Mol. Pharmacol. 63, 9 18.
28. 2-adrenergic receptor dephosphorylation by vesicular acidification. J. Biol. Chem. 272, 5 8.
29. Lajoie P. Nabi I. R. (2007) Regulation of raft-dependent endocytosis. J. Cell Mol. Med. 11, 644 653.
30. Lefkowitz R. J. (2007) Seven transmembrane receptors: something old, something new. Acta Physiol. 190, 9 19.
31. 3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms. Mol. Pharmacol. 74, 338 347.
32. Luttrell L. M. Lefkowitz R. J. (2002) The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J. Cell Sci. 115, 455 465.
33. Marchese A., Paing M. M., Temple B. R. Trejo J. (2008) G protein-coupled receptor sorting to endosomes and lysosomes. Annu. Rev. Pharmacol. Toxicol. 48, 601 629.
34. Martiny-Baron G., Kazanietz M. G., Mischak H., Blumberg P. M., Kochs G., Hug H., Marmé D. Schächtele C. (1993) Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J. Biol. Chem. 268, 9194 9197.
35. Mehdi S. (1991) Cell-penetrating inhibitors of calpain. Trends Biochem. Sci. 16, 150 153.
36. Ménard L., Ferguson S. S., Barak L. S., Bertrand L., Premont R. T., Colapietro A. M., Lefkowitz R. J. Caron M. G. (1996) Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration. Biochemistry 35, 4155 4160.
37. 1 receptor in intact cells. J. Pharmacol. Sci. 96, 474 482.
38. Moore C. A., Milano S. K. Benovic J. L. (2007) Regulation of receptor trafficking by GRKs and arrestins. Annu. Rev. Physiol. 69, 451 482.
39. Mundell S. J., Luo J., Benovic J. L., Conley P. B. Poole A. W. (2006) Distinct clathrin-coated pits sort different G protein-coupled receptor cargo. Traffic 7, 1420 1431.
40. Orlandi P. A. Fishman P. H. (1998) Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J. Cell Biol. 141, 905 915.
41. Pierce K. L. Lefkowitz R. J. (2001) Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors. Nat. Rev. Neurosci. 2, 727 733.
42. 2-adrenergic receptors permit receptor resensitization. Mol. Pharmacol. 47, 666 676.
43. Pitcher J. A., Payne E. S., Csortos C., DePaoli-Roach A. A. Lefkowitz R. J. (1995) The G protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. Proc. Natl Acad. Sci. USA 92, 8343 8347.
44. Puthenveedu M. A. von Zastrow M. (2006) Cargo regulates clathrin-coated pit dynamics. Cell 127, 113 124.
45. Reiter E. Lefkowitz R. J. (2006) GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling. Trends Endocrinol. Metab. 17, 159 165.
46. 1-receptor in CHO-K1 cells. Br. J. Pharmacol. 146, 612 624.
47. 2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases. Mol. Pharmacol. 60, 1049 1056.
48. Shenoy S. K. (2007) Seven-transmembrane receptors and ubiquitination. Circ. Res. 100, 1142 1154.
49. Shenoy S. K. Lefkowitz R. J. (2003) Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem. J. 375, 503 515.
50. 2-adrenergic receptor and beta-arrestin. Science 294, 1307 1313.
51. Slowiejko D. M., McEwen E. L., Ernst S. A. Fisher S. K. (1996) Muscarinic receptor sequestration in SH-SY5Y neuroblastoma cells is inhibited when clathrin distribution is perturbed. J. Neurochem. 88, 186 196.
52. 1 receptor stably expressed in Chinese hamster ovary cells. Br. J. Pharmacol. 117, 1071 1080.
53. 2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 265, 4315 4320.
54. Ushio-Fukai M., Hilenski L., Santanam N., Becker P. L., Ma Y., Griendling K. K. Alexander R. W. (2001) Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells: role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling. J. Biol. Chem. 276, 48269 48275.
55. 1 histamine receptor signaling by G protein-coupled receptor kinase 2 in uterine smooth muscle cells. Mol. Endocrinol. 22, 1893 1907.
56. Wolfe B. L. Trejo J. (2007) Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis. Traffic 8, 462 470.
57. Yang Y., Kitagaki J., Dai R. M. et al. (2007) Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. Cancer Res. 67, 9472 9481.
58. Yu S. S., Lefkowitz R. J. Hausdorff W. P. (1993) ß-adrenergic receptor sequestration: a potential mechanism of receptor resensitization. J. Biol. Chem. 268, 337 341.