The epidemiology of osteonecrosis: Findings from the GPRD and THIN databases in the UK

Osteoporosis International

Volumn 21, Issue 4, 2010, Pages 569-577

  Cooper, C ^a,b,c   Steinbuch, M ^d   Stevenson, R ^d   Miday, R ^d   Watts, N B ^e  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d PROCTER AND GAMBLE COMPANY   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Avascular necrosis; Epidemiology; Osteonecrosis; Risk factors

Indexed keywords

ALENDRONIC ACID; ANTIINFECTIVE AGENT; BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; CORTICOSTEROID; ETIDRONIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; RISEDRONIC ACID;

ADULT; AGE; AGED; ALCOHOL CONSUMPTION; ARTICLE; ASTHMA; BONE NECROSIS; BONE TRANSPLANTATION; CASE CONTROL STUDY; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DATA BASE; DIALYSIS; DRUG USE; ENTERITIS; FEMALE; FRACTURE; GOUT; HIP; HORMONE SUBSTITUTION; HOSPITALIZATION; HUMAN; INCIDENCE; JAW OSTEONECROSIS; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; NEOPLASM; ORGAN TRANSPLANTATION; OSTEOARTHRITIS; OSTEOPOROSIS; PATIENT REFERRAL; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; UNITED KINGDOM;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; CONNECTIVE TISSUE DISEASES; EPIDEMIOLOGIC METHODS; FEMALE; FRACTURES, BONE; GLUCOCORTICOIDS; GREAT BRITAIN; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; OSTEOARTHRITIS; OSTEONECROSIS; OSTEOPOROSIS; SEX DISTRIBUTION; YOUNG ADULT;

EID: 77950930517     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-009-1003-1     Document Type: Article

References (21)

1. Assouline-Dayan Y, Chang C, Greenspan A, Shoenfeld Y, Gershwin ME (2002) Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum 32(2):94-124
2. Tofferi JK, Gilliland W (2008) Avascular Necrosis. Available via eMedicine. http://em.edicine.medscape.coni/article/333364-oveiview. Accessed 20 Feb 2009.
3. Mont MA, Payman RK, Laporte DM, Petri M, Jones LC, Hungerford DS (2000) Atraumatic osteonecrosis of the humeral head. J Rheumatol 27(7):1766-1773
4. 4. Gladman DD, Urowitz MB, Chaudhry-Ahluwalia V, Hallet DC, Cook RJ (2001) Predictive factors for symptomatic osteonecrosis in patients with systemic lupus erythematosus. J Rheumatol 28 (4):761-765 (Pubitemid 32246943)
5. Abu-Shakra M, Buskila D, Shoenfeld Y (2003) Osteonecrosis in patients with SLE. Clin Rev Allergy Immunol 25(1):13-24
6. 6. Mok CC, Lau CS, Wong RW (1998) Risk factors for avascular bone necrosis in systemic lupus erythematosus. Br J Rheumatol 37(8):895-900 (Pubitemid 28393760)
7. Calvo-Alén J, McGwin G, Toloza S, Fernández M, Roseman JM, Bastian HM, Cepeda EJ, González EB, Baethge BA, Fessier BJ, Vila LM, Reveille JD, Alarcón GS, LUMINA Study Group (2006) Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXIV. Cytotoxic treatment is an additional, risk factor for the development of symptomatic osteonecrosis in lupus patients: results of a nested matched case-control study. Ann Rheum Dis 65(6):785-790
8. 8. Etminan M, Aminzadeh K, Matthew IR, Brophy JM. (2008) Use of oral bisphosphonates and the risk of aseptic osteonecrosis: a nested case-control study. J Rheumatol 35(4):691-695 (Pubitemid 351500068)
9. 9. van Staa TP, Cooper C, Leufkens HG, Bishop N (2003) Children and the risk of fractures caused by oral, corticosteroids. J Bone Miner Res 18(5):913-918 (Pubitemid 37294976)
10. van Staa TP, Abenhaim L (1994) The quality of information recorded on a UK database of primary care records: a study of hospitalization due to hypoglycemia and other conditions. Pharmacoepidemiol Drug Saf 3(1):15-21
11. van Staa TP, Abenhaim. L, Cooper C, Zhang B, Leufkens HG (2000) The use of a large pharmacoepidemiological database to study exposure to oral, corticosteroids and risk of fractures: validation of study population and results. Pharmacoepidemiol Drug Saf 9(5):359-366
12. 12. Wurst KE, Ephross SA, Loehr J, Clark DW, Guess HA (2007) The utility of the general, practice research database to examine selected congenital heart defects: a validation study. Pharmacoepidemiol Drug Saf 16(8):867-877 (Pubitemid 47322586)
13. Thomas SL, Edwards CJ, Smeeth L, Cooper C, Hall AJ (2008) How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database. Arthritis Rheum 59(9):1314-1321
14. Lewis JD, Schinnar R, Bilker WB, Wang X, Strom BL (2007) Validation studies of the health improvement network. (THIN) database for pharmacoepidemiology research. Pharmacoepidemiol Drug Saf 16(4):393-401
15. 15. Fink JC, Leisenring WM, Sullivan KM, Sherrard DJ, Weiss NS (1998) Avascular necrosis following bone marrow transplantation: a case-control study. Bone 22(1):67-71. (Pubitemid 28033655)
16. Rizzoli R, Burlet N, Cahall D, Delmas PD, Eriksen EF, Feisenberg D, Grbic J, Jontell M, Landesberg R, Laslop A, Wollenhaupt M, Papapoulos S, Sezer O, Sprafka M, Reginster JY (2008) Osteonecrosis of the jaw and bisphosphonate treatment for osteoporosis. Bone 42(5):841-847
17. 17. Woo SB, Hellstein JW, Kalmar JR (2006) Systematic review: bisphosphonates and osteonecrosis of the jaws. Ann Intern Med 144(10):753-761 (Pubitemid 46780635)
18. 18. Ruggiero SL, Mehrotra B, Rosenberg TJ, Engroff SL (2004) Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. J Oral Maxillofac Surg 62(5):527-534 (Pubitemid 38542516)
19. Marx RE (2003) Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg 61(9):1115-1117
20. 20. Talamo G, Angtuaco E, Walker RC, Dong L, Miceli MH, Zangan M, Tricot G, Barlogie B, Anaissie E (2005) Avascular necrosis of femoral and/or humeral heads in multiple myeloma: results of a prospective study of patients treated with, dexamethasone-based regimens and high-dose chemotherapy. J Clin Oncol 23(22):5217-5223 (Pubitemid 46224032)
21. McKown K (2007) Osteonecrosis. Available via American College of Rheumatology. http://www.rheumatoIogy.org/public/ factsheets/diseases-and- conditions/osteonecrosis.asp?aud=pat. Accessed. 20 Feb 2009.