AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1A1-Ren2 transgenic rats fed with a high-salt diet

American Journal of the Medical Sciences

Volumn 339, Issue 4, 2010, Pages 356-361

  Williams, Dustyn E ^a   Prieto, Minolfa C ^a   Mullins, John J ^b   Navar, L Gabriel ^a   Mitchell, Kenneth D ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Kidney; Malignant hypertension; Radioimmunoassay; Renin angiotensin system; Sodium dependent

Indexed keywords

3 INDOLEMETHANOL; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; CYTOCHROME P450 1A1; LOSARTAN; RENIN; ANGIOTENSIN 1 RECEPTOR; ANTIHYPERTENSIVE AGENT; REN2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; GENE EXPRESSION; KIDNEY CORTEX; KIDNEY MEDULLA; LETHARGY; MALE; MALIGNANT HYPERTENSION; NONHUMAN; RADIOIMMUNOASSAY; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SALT INTAKE; SYSTOLIC BLOOD PRESSURE; TRANSGENIC RAT; WEIGHT CHANGE; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; HYPERTENSION; KIDNEY; METABOLISM; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CYTOCHROME P-450 CYP1A1; HYPERTENSION; KIDNEY; LOSARTAN; MALE; MICE; RATS; RATS, TRANSGENIC; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN; SODIUM CHLORIDE, DIETARY;

EID: 77950927320     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e3181d2b0a8     Document Type: Article

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