Fragmented QRS in Prediction of Cardiac Deaths and Heart Failure Hospitalizations after Myocardial Infarction

Annals of Noninvasive Electrocardiology

Volumn 15, Issue 2, 2010, Pages 130-137

  Korhonen, Petri ^a   Husa, Terhi ^a   Konttila, Teijo ^b   Tierala, Ilkka ^a   Mäkijärvi, Markku ^a   Väänänen, Heikki ^b   Ojanen, Janne ^b   Vehtari, Aki ^b   Toivonen, Lauri ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b AALTO UNIVERSITY   (Finland)

Author keywords

Cardiac death; Heart failure; QRS fragmentation

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ACCURACY; ADULT; AGED; ARTICLE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIABETES MELLITUS; DISEASE ASSOCIATION; ELECTROCARDIOGRAM; FEMALE; FOLLOW UP; HEART ATRIUM FIBRILLATION; HEART BUNDLE BRANCH BLOCK; HEART DEATH; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PRIORITY JOURNAL; QRS COMPLEX; RISK ASSESSMENT; SIGNAL PROCESSING; COMPLICATION; DEATH; ELECTROCARDIOGRAPHY; KAPLAN MEIER METHOD; MIDDLE AGED; PREDICTIVE VALUE; PROCEDURES; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; REPRODUCIBILITY; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

DEATH; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HOSPITALIZATION; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RISK FACTORS; ROC CURVE; SIGNAL PROCESSING, COMPUTER-ASSISTED; KAPLAN-MEIER ESTIMATE;

EID: 77950899735     PISSN: 1082720X     EISSN: 1542474X     Source Type: Journal    
DOI: 10.1111/j.1542-474X.2010.00353.x     Document Type: Article

References (23)

1. Torabi A, Cleland JGF, Khan NK, et al. The timing of development and subsequent clinical course of heart failure after a myocardial infarction. Eur Heart J 2008 29 : 859 870. (Pubitemid 351499497)
2. Lewis EF, Velazques EJ, Solomon SD, et al. Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction: A VALIANT study. Eur Heart J 2008 29 : 748 756.
3. Velagaleti RS, Pencina MJ, Murabito JM, et al. Long-term trends in the incidence of heart failure after myocardial infarction. Circulation 2008 118 : 2057 2062.
4. The SOLVD Investigators. Effect of enalapril on survival of patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991 325 : 293 302.
5. Bristow MR, Saxon LA, Boehmer J, et al. Cardiac-Resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med 2004 350 : 2140 2150.
6. Das MK, Saha C, El Masry H, et al. Fragmented QRS on a 12-lead ECG: A predictor of mortality and cardiac events in patients with coronary artery disease. Heart Rhythm 2007 4 : 1385 1392. (Pubitemid 47578530)
7. Pietrasik G, Goldenberg I, Zdzienicka J, et al. Prognostic significance of fragmented QRS complex for predicting the risk of recurrent cardiac events in patients with q-wave myocardial infarction. Am J Cardiol 2007 100 : 583 586. (Pubitemid 47223130)
8. Bode-Schurnubs L, Böcker D, Block M, et al. QRS duration: A simple marker for predicting cardiac mortality in ICD patients with heart failure. Heart 2003 89 : 1157 1162. (Pubitemid 37164003)
9. Bauer A, Watanabe MA, Barthel P, et al. QRS duration and late mortality in unselected post-infarction patients of the revascularization era. Eur Heart J 2006 27 : 427 433. (Pubitemid 43209167)
10. Hänninen H, Takala P, Mäkijärvi M, et al. Recording locations in multichannel magnetocardiography and body surface potential mapping sensitive for regional exercise-induced myocardial ischemia. Basic Res Cardiol 2001 96 : 405 414. (Pubitemid 32700578)
11. Simson MB. Use of signals in the terminal QRS complex to identify patients with ventricular tachycardia after myocardial infarction. Circulation 1981 64 : 235 242.
12. Müller H-P, Gödde P, Czerski K, et al. Magnetocardiographic analysis of the two-dimensional distribution of intra-QRS fractionated activation. Phys Med Biol 1999 44 : 105 120. (Pubitemid 29062230)
13. Cleland JG, Erhardt L, Hall AS, et al. Validation of primary and secondary outcomes and classification of mode of death among patients with clinical evidence of heart failure after a myocardial infarction: A report from the Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. J Cardiovasc Pharmacol 1993 22 (Suppl. 9 S22 S27. (Pubitemid 24089992)
14. Saumarez RC, Pytkowski M, Sterlinski M, et al. Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrofic cardiomyopathy. Eur Heart J 2008 29 : 1653 1661. (Pubitemid 351957538)
15. Morita H, Kusano KF, Miura D, et al. Fragmented QRS as a marker of conduction abnormality and a predictor of prognosis of Brugada syndrome. Circulation 2008 118 : 1697 1704.
16. Lander P, Gomis P, Goyal R, et al. Analysis of abnormal intra-QRS potentials. Improved predictive value for arrhythmic events with the signal averaged electrocardiogram. Circulation 1997 95 : 1386 1393. (Pubitemid 27142794)
17. De Bakker JMT, Van Capelle FJL, Janse MJ, et al. Fractionated electrograms in dilated cardiomyopathy: Origin and relation to abnormal conduction. J Am Coll Cardiol 1996 27 : 1071 1078. (Pubitemid 26117694)
18. Lagner PH, Geselowitz DB. Characteristics of the frequency spectrum in the normal electrocardiogram and in subjects following myocardial infarction. Circ Res 1960 8 : 577 584.
19. Flowers NC, Horan LG, Thomas JR, et al. The anatomic basis for high-frequency components in the electrocardiogram. Circulation 1969 39 : 531 539.
20. Flowers NC, Horan LG, Tolleson WJ, et al. Localization of the site of myocardial scarring in man by high-frequency components. Circulation 1969 40 : 927 934.
21. Das MK, Khan B, Jacob S, et al. Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease. Circulation 2006 113 : 2495 2501. (Pubitemid 43948027)
22. Hood MA, Pogwizd SM, Patrick J, et al. Contribution of myocardium responsible for ventricular tachycardia to abnormalities detected by analysis of signal-averaged electrocardiograms. Circulation 1992 86 : 1888 1901.
23. Yerra L, Anavekar N, Skali H, et al. Association of QRS duration and outcomes after myocardial infarction: The VALIANT trial. Heart Rhythm 2006 3 : 313 316. (Pubitemid 43264408)