Staphylococcus aureus carriage in care homes: Identification of risk factors, including the role of dementia

Epidemiology and Infection

Volumn 138, Issue 5, 2010, Pages 686-696

  Lasseter, G ^a   Charlett, A ^a   Lewis, D ^a   Donald, I ^b   Howell Jones, R ^a   McNulty, C A M ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

Author keywords

Dementia; Epidemiology; Hand hygiene; Methicillin resistant S. aureus (MRSA); Staphylococcus aureus

Indexed keywords

AGAR MEDIUM; AGED; ARTICLE; BACTERIUM CULTURE; CLINICAL ASSESSMENT; CROSS INFECTION; DEMENTIA; DISEASE TRANSMISSION; FEMALE; HEALTH CARE PERSONNEL; HOSPITALIZATION; HUMAN; INFECTION CONTROL; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MINI MENTAL STATE EXAMINATION; NASOGASTRIC TUBE; NOSE SMEAR; PREVALENCE; RESIDENTIAL CARE; RISK ASSESSMENT; SAMPLE SIZE; SCREENING; TRACHEOTOMY; URINARY CATHETER; HETEROZYGOTE; HOME FOR THE AGED; ISOLATION AND PURIFICATION; MICROBIOLOGY; NOSE; NURSING HOME; RISK FACTOR; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; UNITED KINGDOM;

AGED; AGED, 80 AND OVER; CARRIER STATE; CROSS INFECTION; DEMENTIA; FEMALE; GREAT BRITAIN; HOMES FOR THE AGED; HUMANS; MALE; NOSE; NURSING HOMES; PREVALENCE; RISK FACTORS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 77950886693     PISSN: 09502688     EISSN: 14694409     Source Type: Journal    
DOI: 10.1017/S0950268810000233     Document Type: Article

References (37)

1. Cosgrove SE, et al. The impact of methicillin resistance in bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infection Control and Hospital Epidemiology 2005; 26: 166-174.
2. Cosgrove SE, et al. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clinical Infectious Diseases 2003; 36: 53-59.
3. Delaney JA, et al. Mortality after infection with methicillin- resistant Staphylococcus aureus (MRSA) diagnosed in the community. BMC Medicine 2008; 6: 2.
4. Davis KA, et al. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent infection. Clinical Infectious Diseases 2004; 39: 776-782.
5. National Statistics. Ageing - fastest increase in the 'oldest old'. National Statistics Online 2009 (http:// www.statistics.gov.uk/cci/nugget.asp? ID=949). Accessed 26 November 2009.
6. West Midlands Public Health Observatory. Indications of Public Health in the English Regions 9: Older People. Association of Public Health Observatories, 2008.
7. Drinka P, et al. Adverse events associated with methicillin-resistant Staphylococcus aureus in a nursing home. Archives of Internal Medicine 2001; 161: 2371-2377.
8. Lucet J-C, et al. High prevalence of carriage of methicillin- resistant Staphylococcus aureus at hospital admission in elderly patients : implications for infection control strategies. Infection Control and Hospital Epidemiology 2005; 26: 121-126.
9. Jernigan JA, et al. Prevalence of and risk factors for colonization with methicillin-resistant Staphylococcus aureus at the time of hospital admission. Infection Control and Hospital Epidemiology 2003; 24: 409-414.
10. Cox RA, Bowie PE. Methicillin-resistant Staphylococcus aureus colonization in nursing home residents : a prevalence study in Northamptonshire. Journal of Hospital Infection 1999; 43: 115-122.
11. Fraise AP, et al. Methicillin-resistant Staphylcoccus aureus (MRSA) in nursing homes in a major UK city : an anonymized point prevalence survey. Epidemiology and Infection 1997; 118: 1-5.
12. Namnyak S, et al. Methicillin-resistant Staphylcoccus aureus : a questionnaire and microbiological survey of nursing and residential homes in Barking, Havering and Brentwood. Journal of Infection 1998; 36: 67-72.
13. Barr B, et al. Prevalence of methicillin-resistant Staphylococcus aureus colonization among older residents of care homes in the United Kingdom. Infection Control and Hospital Epidemiology 2007; 28: 853-859.
14. O'Sullivan NPO, Keane CT. Risk factors for colonization with methicillin-resistant Staphylococcus aureus among nursing home residents. Journal of Hospital Infection 2000; 45: 206-210.
15. Alzheimer's Society. Dementia UK: a report into the prevalence and cost of dementia. Alzheimer's Society, 2007 (http://www.alzheimers.org.uk/site/ scripts/ download-info.php?fileID=1). Accessed 10 August 2009.
16. Suetens C, et al. Methicillin-resistant Staphylococcus aureus colonization is associated with higher mortality in nursing home residents with impaired cognitive status. Journal of the American Geriatric Society 2006; 54: 1854-1860.
17. Office of National Statistics. Correction: current estimates - population estimates by ethnic group mid-2007 (experimental) (http://www.statistics.gov. uk/downloads/ theme-population/Tables-EE1-EE6-2007.xls). Accessed 9 October 2009.
18. Indices of Deprivation 2007. Communities and Local Government 2009 (http://www.communities.gov.uk/ communities/neighbourhoodrenewal/deprivation/ deprivation07/). Accessed 26 November 2009.
19. McNulty CAM, et al. Is there an opportunity to reduce urinary catheter-related infections ? Exploring variation in catheterisation rates in care homes. British Journal of Infection Control 2006; 7: 22-28.
20. Shulman KI. Clock-drawing: is it the ideal cognitive screening test ? International Journal of Geriatric Psychiatry 2000; 15: 548-561.
21. Shulman KI, et al. Clock-drawing and dementia in the community: a longitudinal study. International Journal of Geriatric Psychiatry 1993; 8: 487-496.
22. Brodaty H, Moore CM. The clock drawing test for dementia of the Alzheimer's type: a comparison of three scoring methods in a memory disorder clinic. International Journal of Geriatric Psychiatry 1997; 12: 619-627
23. Scanlan JM, et al. Comparing clock tests for dementia screening : naive judgements vs formal systems - what is optimal? International Journal of Geriatric Psychiatry 2002; 17: 14-21.
24. van der Burg M, et al. Scoring clock tests for dementia screening : a comparison of two scoring methods. International Journal of Geriatric Psychiatry 2004; 19: 685-689.
25. Antonelli Incalzi R, et al. Construct validity of the Abbreviated Mental Test in older medical inpatients. Dementia and Geriatric Cognitive Disorders 2003; 15: 199-206.
26. Brown DFJ, et al. Guidelines for the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). Journal of Antimicrobial Chemotherapy 2005; 56: 1000-1018.
27. Health Protection Agency. Specimens for screening for MRSA. Standard Operating Procedure 2008, 29(5.1) (http://www.hpa-standardmethods.org.uk/ documents/ bsop/pdf/bsop29.pdf). Accessed 26 October 2009.
28. Health Protection Agency. Identification of Staphylococcus species, Micrococcus species and Rothia species. Standard Operating Procedure 2007, 7(2.1) (http:// www.hpa-standardmethods.org.uk/documents/bsopid/ pdf/bsopid7.pdf). Accessed 26 October 2009.
29. Coia JE, et al. Guidelines for the control and prevention of meticillin-resistant Staphylococcus aureus (MRSA) in healthcare facilities. Journal of Hospital Infection 2006; 63S: S1-S44.
30. von Baum H, et al. Risk factors for methicillin-resistant Staphylococcus aureus carriage in residents of German nursing homes. Infection Control and Hospital Epidemiology 2002; 23: 511-515.
31. Dall'Antonia M, et al. Competition between methicillinsensitive and -resistant Staphylococcus aureus in the anterior nares. Journal of Hospital Infection 2005; 61: 62-67.
32. Mental Capacity Act 2005. Department of Constitutional Affairs, Office of Public Sector Information (2007) (http://www.opsi.gov.uk/ACTS/acts2005/ukpga- 20050009-en-1). Accessed 7 January 2010.
33. Peters C, Redding P, Allardice G. MRSA Screening: is one nose swab enough? Federation of Infection Societies 2009; Poster Presentation (P169). ICC Birmingham.
34. Nahimana I, Francioli P, Blanc DS. Evaluation of three chromogenic media (MRSA-ID, MRSA-Select and CHROMagar MRSA) and ORSAB for surveillance cultures of methicillin-resistant Staphylococcus aureus. Clinical Microbiology and Infection 2006; 12: 1168-1174.
35. Nonhoff C, et al. Comparison of three chromogenic media and enrichment broth media for the detection of methicillin-resistant Staphylococcus aureus from mucocutaneous screening specimens: comparison of MRSA chromogenic media. European Journal of Clinical Microbiology and Infectious Diseases 2009; 28: 363-369.
36. National Patient Safety Agency. Ready, steady, go! The full guide to implementing the cleanyourhands campaign in your Trust, 2004 (http://www.npsa.nhs.uk/ cleanyourhands/). Accessed 26 October 2009.
37. Health Protection Agency. Introduction to infection control in care homes. DVD 2009 (http://194.74.226.162/ HPA/Publications/InfectiousDiseases/ InfectionControl/ 1229594195568/). Accessed 26 October 2009.