Effects of Kuntai Capsule and hormone replacement therapy on cognitive function and mental symptoms of early postmenopausal women: A randomized controlled trial

Journal of Chinese Integrative Medicine

Volumn 8, Issue 4, 2010, Pages 321-327

  Li, Wen Juan ^a   Xu, Liang Zhi ^a   Liu, Hong Wei ^a   Zhang, Jing ^a   Tang, Liu Lin ^a   Zhou, Ling Ling ^a   Zhuang, Jing ^a   Liu, Ying ^a   Liu, Xiao Fang ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Chinese herbal drug; Cognition; Estrogen replacement therapy; Perimenopause; Randomized controlled trial

Indexed keywords

CHINESE DRUG; CONJUGATED ESTROGEN; KUNTAI; MEDROXYPROGESTERONE ACETATE; UNCLASSIFIED DRUG;

ADULT; ADVERSE OUTCOME; ARTICLE; CHINA; CLINICAL TRIAL; COGNITION; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG CAPSULE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; ESTROGEN THERAPY; FEMALE; HORMONE SUBSTITUTION; HUMAN; MAJOR CLINICAL STUDY; MENTAL DISEASE; MINI MENTAL STATE EXAMINATION; OUTPATIENT DEPARTMENT; POSTMENOPAUSE; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; TREATMENT OUTCOME; VAGINA BLEEDING;

ADULT; COGNITION; DRUGS, CHINESE HERBAL; ESTROGENS, CONJUGATED (USP); FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; MENOPAUSE; MENTAL PROCESSES; MIDDLE AGED; PHYTOTHERAPY; POSTMENOPAUSE;

EID: 77950885864     PISSN: 16721977     EISSN: None     Source Type: Journal    
DOI: 10.3736/jcim20100404     Document Type: Article

References (13)

1. Plassman BL, Langa KM, Fisher GG, Heeringa SG, Weir DR, Ofstedal MB, Burke JR, Hurd MD, Potter GG, Rodgers WL, Steffens DC, Willis RJ, Wallace RB. Prevalence of dementia in the United States: The aging, demographics and memory study. Neuroepidemiology. 2007; 29 (1-2): 125-132.
2. Wang HL, Yu X. Current status in epidemiological studies on Alzheimer disease in China. Zhonghua Quan Ke Yi Shi Za Zhi. 2006; 5 (6): 358-360. Chinese with abstract in English.
3. Chen R, Chen JY, Lin SQ, Chai LN, Li DM, Zhang Y, Jiang Y, Chen FL. Effects of Kuntai capsule on climacteric syndrome: randomized, double-blinded, parallel-controlled clinical trial. Zhongguo Fu You Bao Jian. 2005; 20 (14): 1751-1754. Chinese with abstract in English.
4. Zhang SF, Liu Y, Xie Q, Bi CP, Zhu HT, Ha LX, Jiang J, Xia X, Zhou KM, Liu JH. Effects of gengnianningxin capsule on the histomorphology of ovarin and uterine in the menopausal rats. Zhonghua Lao Nian Yi Xue Za Zhi. 2004; 23 (9): 648-651. Chinese with abstract in English.
5. Tang Y. Material basis and mechanisms of efficacy of Kuntai Capsule in preventive treatment of female meno pausal syndrome. Chengdu: Doctor Thesis of Chengdu 10 University of Tradtional Chinese Medicine. 2003. Chinese.
6. Chen S, Nilsen J, Brinton RD. Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: therapeutic implications. Endocrinology. 2006; 147 (11): 5303-5313. (Pubitemid 44790585)
7. Gong LL, Zhang SF, Ji L. Effect of hormone and Chinese traditional medicine treatment on cognition and memory and quality of life in the women at the early stage of menopause. Sheng Zhi Yu Bi Yun. 2008; 28 (1) : 26-31. Chinese with abstract in English.
8. Lethaby A, Hogervorst E, Richards M, Yesufu A, Yaffe K. Hormone replacement therapy for cognitive function in postmenopausal women. Cochrane Database Syst Rev. 2008; (3): CD003122. (Pubitemid 351807570)
9. Tierney MC, Oh P, Moineddin R, Greenblatt EM, Snow WG, Fisher RH, Iazzetta J, Hyslop PS, MacLusky NJ. A randomized double-blind trial of the effects of hormone therapy on delayed verbal recall in older women. Psychoneuroendocrinology. 2009; 34 (7): 1065-1074.
10. Brinton RD. Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action. Ann N Y Acad Sci. 2005; 1052: 57-74.
11. Zhang J, Gong LL, Zhang SF, Chen X, Ji L, Xu Y, Zhou YQ. Effects of Kuntai Capsule on quality of life, breast distending pain and vaginal bleeding in women at early stage of menopause. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008; 28 (11): 972-976. Chinese with abstract in English.
12. Wang SH, Lin SQ, Gui QF, Jin MJ, Jiang Y. Profiles of irregular bleeding induced by low-dose hormone therapy and Chinese formulated herbs products. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006; 28 (2): 256-261. Chinese with abstract in English. (Pubitemid 43826743)
13. Carranza-Lira S, Velasco Diaz G, Olivares A, Chán Verdugo R, Herrera J. Correlation of Kupperman's index with estrogen and androgen levels, according to weight and body fat distribution in postmenopausal women from Mexico City. Int J Fertil Womens Med. 2006; 51 (2): 83-88. (Pubitemid 44050272)