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Volumn 123, Issue 7, 2010, Pages 954-960

Leukemia stem cells in drug resistance and metastasis

Author keywords

Cancer stem cells; Drug resistance; Leukemia; Metastasis

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; BETA CATENIN; CD123 ANTIGEN; CD19 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD7 ANTIGEN; CD9 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; GELATINASE B; GEMTUZUMAB OZOGAMICIN; HERMES ANTIGEN; IMATINIB; JANUS KINASE; K RAS PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; NOTCH1 RECEPTOR; PROTEIN BCL 2; STAT PROTEIN; STEM CELL FACTOR RECEPTOR; STROMAL CELL DERIVED FACTOR 1; THROMBOPOIETIN RECEPTOR; THY 1 ANTIGEN; TRANSCRIPTION FACTOR RUNX1; UNINDEXED DRUG; WNT PROTEIN;

EID: 77950874189     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.07.034     Document Type: Review
Times cited : (18)

References (84)
  • 1
    • 3242754448 scopus 로고    scopus 로고
    • Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
    • Hope KJ, Jin LQ, Dick JE. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol 2004; 5: 738-743.
    • (2004) Nat Immunol , vol.5 , pp. 738-743
    • Hope, K.J.1    Jin, L.Q.2    Dick, J.E.3
  • 2
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Cortes JC, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994; 367: 645-648.
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3    Murdoch, B.4    Hoang, T.5    Cortes, J.C.6
  • 3
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-737.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 4
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Dick JE. Stem cell concepts renew cancer research. Blood 2008; 112: 4793-4807.
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 6
    • 67649171660 scopus 로고    scopus 로고
    • TEL-AML1 corrupts hematopoietic stem cells to persist in the bone marrow and initiate leukemia
    • Schindler JW, Van Buren D, Foudi A, Krejci O, Qin J, Orkin SH, et al. TEL-AML1 corrupts hematopoietic stem cells to persist in the bone marrow and initiate leukemia. Cell Stem Cell 2009; 5: 43-53.
    • (2009) Cell Stem Cell , vol.5 , pp. 43-53
    • Schindler, J.W.1    van Buren, D.2    Foudi, A.3    Krejci, O.4    Qin, J.5    Orkin, S.H.6
  • 9
    • 33746498580 scopus 로고    scopus 로고
    • Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
    • Krivtsov AV, Twomey D, Feng ZH, Stubbs MC, Wang YZ, Faber G, et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006; 442: 818-822.
    • (2006) Nature , vol.442 , pp. 818-822
    • Krivtsov, A.V.1    Twomey, D.2    Feng, Z.H.3    Stubbs, M.C.4    Wang, Y.Z.5    Faber, G.6
  • 12
    • 33846242910 scopus 로고    scopus 로고
    • Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia
    • Cox CV, Martin HM, Kearns PR, Virgo P, Evely RS, Blair A. Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia. Blood 2007; 109: 674-682.
    • (2007) Blood , vol.109 , pp. 674-682
    • Cox, C.V.1    Martin, H.M.2    Kearns, P.R.3    Virgo, P.4    Evely, R.S.5    Blair, A.6
  • 13
    • 13944274492 scopus 로고    scopus 로고
    • Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive-restricted CD34+/CD19- cells
    • Hotfilder M, Rottgers S, Rosemann A, Iwata S, Dang NH, Inukai T, et al. Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive-restricted CD34+/CD19- cells. Cancer Res 2005; 65: 1442-1449.
    • (2005) Cancer Res , vol.65 , pp. 1442-1449
    • Hotfilder, M.1    Rottgers, S.2    Rosemann, A.3    Iwata, S.4    Dang, N.H.5    Inukai, T.6
  • 14
    • 65049090853 scopus 로고    scopus 로고
    • CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells
    • Yamazaki H, Nishida H, Iwata S, Dang NH, Morimoto C. CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells. Biochem Biophys Res Commun 2009; 383: 172-177.
    • (2009) Biochem Biophys Res Commun , vol.383 , pp. 172-177
    • Yamazaki, H.1    Nishida, H.2    Iwata, S.3    Dang, N.H.4    Morimoto, C.5
  • 16
    • 33749515476 scopus 로고    scopus 로고
    • Targeting of CD44 eradicates human acute myeloid leukemic stem cells
    • Jin LQ, Hope KJ, Zhai QL, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 2006; 12: 1167-1174.
    • (2006) Nat Med , vol.12 , pp. 1167-1174
    • Jin, L.Q.1    Hope, K.J.2    Zhai, Q.L.3    Smadja-Joffe, F.4    Dick, J.E.5
  • 19
    • 0034097928 scopus 로고    scopus 로고
    • Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117)
    • Blair A, Sutherland HJ. Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117). Exp Hematol 2000; 28: 660-671.
    • (2000) Exp Hematol , vol.28 , pp. 660-671
    • Blair, A.1    Sutherland, H.J.2
  • 20
    • 0033815950 scopus 로고    scopus 로고
    • The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells
    • Jordan CT, Upchurch D, Szilvassy SJ, Guzman ML, Howard DS, Pettigrew AL, et al. The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells. Leukemia 2000; 14: 1777-1784.
    • (2000) Leukemia , vol.14 , pp. 1777-1784
    • Jordan, C.T.1    Upchurch, D.2    Szilvassy, S.J.3    Guzman, M.L.4    Howard, D.S.5    Pettigrew, A.L.6
  • 21
    • 20144374544 scopus 로고    scopus 로고
    • Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease
    • Eisterer W, Jiang X, Christ O, Glimm H, Lee KH, Pang E, et al. Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease. Leukemia 2005; 19: 435-441.
    • (2005) Leukemia , vol.19 , pp. 435-441
    • Eisterer, W.1    Jiang, X.2    Christ, O.3    Glimm, H.4    Lee, K.H.5    Pang, E.6
  • 22
    • 33749521890 scopus 로고    scopus 로고
    • Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells
    • Krause DS, Lazarides K, von Andrian UH, Van Etten RA. Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells. Nat Med 2006; 12: 1175-1180.
    • (2006) Nat Med , vol.12 , pp. 1175-1180
    • Krause, D.S.1    Lazarides, K.2    von Andrian, U.H.3    van Etten, R.A.4
  • 23
    • 33645514001 scopus 로고    scopus 로고
    • A side order of stem cells: The SP phenotype
    • Challen GA, Little MH. A side order of stem cells: the SP phenotype. Stem Cells 2006; 24: 3-12.
    • (2006) Stem Cells , vol.24 , pp. 3-12
    • Challen, G.A.1    Little, M.H.2
  • 25
    • 33750302541 scopus 로고    scopus 로고
    • SP analysis may be used to identify cancer stem cell populations
    • Hadnagy A, Gaboury L, Beaulieu R, Balicki D. SP analysis may be used to identify cancer stem cell populations. Exp Cell Res 2006; 312: 3701-3710.
    • (2006) Exp Cell Res , vol.312 , pp. 3701-3710
    • Hadnagy, A.1    Gaboury, L.2    Beaulieu, R.3    Balicki, D.4
  • 26
    • 58049211689 scopus 로고    scopus 로고
    • Identification of a small subpopulation of candidate leukemia-initiating cells in the side population of patients with acute myeloid leukemia
    • Moshaver B, van Rhenen A, Kelder A, Van der pol M, Termijn M, Bachas C, et al. Identification of a small subpopulation of candidate leukemia-initiating cells in the side population of patients with acute myeloid leukemia. Stem Cells 2008; 26: 3059-3067.
    • (2008) Stem Cells , vol.26 , pp. 3059-3067
    • Moshaver, B.1    van Rhenen, A.2    Kelder, A.3    van der pol, M.4    Termijn, M.5    Bachas, C.6
  • 27
    • 52449091004 scopus 로고    scopus 로고
    • Drug-selected human lung cancer stem cells: Cytokine network, tumorigenic and metastatic properties
    • Levina V, Marrangoni AM, DeMarco R, Gorelik E, Lokshin AE. Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS One 2008; 3: e3077.
    • (2008) PLoS One , vol.e3077 , pp. 3
    • Levina, V.1    Marrangoni, A.M.2    Demarco, R.3    Gorelik, E.4    Lokshin, A.E.5
  • 28
    • 44249127696 scopus 로고    scopus 로고
    • Suspension culture combined with chemotherapeutic agents for sorting of breast cancer stem cells
    • Li HZ, Yi TB, Wu ZY. Suspension culture combined with chemotherapeutic agents for sorting of breast cancer stem cells. BMC Cancer 2008; 8: 135.
    • (2008) BMC Cancer , vol.8 , pp. 135
    • Li, H.Z.1    Yi, T.B.2    Wu, Z.Y.3
  • 29
    • 70349157505 scopus 로고    scopus 로고
    • Enrichment of cancer stem cells based on heterogeneity of invasiveness
    • Yu SC, Bian XW. Enrichment of cancer stem cells based on heterogeneity of invasiveness. Stem Cell Rev 2009; 5: 66-71.
    • (2009) Stem Cell Rev , vol.5 , pp. 66-71
    • Yu, S.C.1    Bian, X.W.2
  • 30
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002; 2: 48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 31
    • 0036100195 scopus 로고    scopus 로고
    • Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)
    • van den Heuvel-Eibrink MM, Wiemer EA, Prins A, Meijerink JP, Vossebeld PJ, van der Holt B, et al. Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML). Leukemia 2002; 16: 833-839.
    • (2002) Leukemia , vol.16 , pp. 833-839
    • van den Heuvel-Eibrink, M.M.1    Wiemer, E.A.2    Prins, A.3    Meijerink, J.P.4    Vossebeld, P.J.5    van der Holt, B.6
  • 32
  • 34
    • 40649100954 scopus 로고    scopus 로고
    • MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia
    • Ho MM, Hogge DE, Ling V. MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia. Exp Hematol 2008; 36: 433-442.
    • (2008) Exp Hematol , vol.36 , pp. 433-442
    • Ho, M.M.1    Hogge, D.E.2    Ling, V.3
  • 35
    • 43249119125 scopus 로고    scopus 로고
    • Determination of P-Glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia
    • de Figueiredo-Pontes LL, Pintão MC, Oliveira LC, Dalmazzo LF, Jácomo RH, Garcia AB, et al. Determination of P-Glycoprotein, MDR-related protein 1, breast cancer resistance protein, and lung-resistance protein expression in leukemic stem cells of acute myeloid leukemia. Cytometry B Clin Cytom 2008; 74B: 163-168.
    • (2008) Cytometry B Clin Cytom , vol.74 B , pp. 163-168
    • de Figueiredo-Pontes, L.L.1    Pintão, M.C.2    Oliveira, L.C.3    Dalmazzo, L.F.4    Jácomo, R.H.5    Garcia, A.B.6
  • 36
    • 36649002031 scopus 로고    scopus 로고
    • Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo
    • Zhao C, Blum J, Chen A, Kwon HY, Jung SH, Cook JM, et al. Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell 2007; 12: 528-541.
    • (2007) Cancer Cell , vol.12 , pp. 528-541
    • Zhao, C.1    Blum, J.2    Chen, A.3    Kwon, H.Y.4    Jung, S.H.5    Cook, J.M.6
  • 37
    • 58249120738 scopus 로고    scopus 로고
    • β-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia
    • Hu Y, Chen Y, Douglas L, Li S. β-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia. Leukemia 2009; 23: 109-116.
    • (2009) Leukemia , vol.23 , pp. 109-116
    • Hu, Y.1    Chen, Y.2    Douglas, L.3    Li, S.4
  • 39
    • 33947254016 scopus 로고    scopus 로고
    • Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: A new paradigm for combination therapy in solid cancers
    • Feldmann G, Dhara S, Fendrich V, Bedja D, Beaty R, Mullendore M, et al. Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer Res 2007; 67: 2187-2196.
    • (2007) Cancer Res , vol.67 , pp. 2187-2196
    • Feldmann, G.1    Dhara, S.2    Fendrich, V.3    Bedja, D.4    Beaty, R.5    Mullendore, M.6
  • 40
    • 50649118068 scopus 로고    scopus 로고
    • Expansion of Bcr-Abl-positive leukemic stem cells is dependent on hedgehog pathway activation
    • Dierks C, Beigi R, Guo GR, Zirlik K, Stegert MR, Manley P, et al. Expansion of Bcr-Abl-positive leukemic stem cells is dependent on hedgehog pathway activation. Cancer Cell 2008; 14: 238-249.
    • (2008) Cancer Cell , vol.14 , pp. 238-249
    • Dierks, C.1    Beigi, R.2    Guo, G.R.3    Zirlik, K.4    Stegert, M.R.5    Manley, P.6
  • 41
    • 64749091867 scopus 로고    scopus 로고
    • Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
    • Zhao C, Chen A, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J, et al. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature 2009; 458: 776-779.
    • (2009) Nature , vol.458 , pp. 776-779
    • Zhao, C.1    Chen, A.2    Jamieson, C.H.3    Fereshteh, M.4    Abrahamsson, A.5    Blum, J.6
  • 42
    • 65349188910 scopus 로고    scopus 로고
    • Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells
    • Kobune M, Takimoto R, Murase K, Iyama S, Sato T, Kikuchi S, et al. Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells. Cancer Sci 2009; 100: 948-955.
    • (2009) Cancer Sci , vol.100 , pp. 948-955
    • Kobune, M.1    Takimoto, R.2    Murase, K.3    Iyama, S.4    Sato, T.5    Kikuchi, S.6
  • 43
    • 33744457653 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia
    • Martelli AM, Nyakern M, Tabellini G, Bortul R, Tazzari PL, Evangelisti C, et al. Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia. Leukemia 2006; 20: 911-928.
    • (2006) Leukemia , vol.20 , pp. 911-928
    • Martelli, A.M.1    Nyakern, M.2    Tabellini, G.3    Bortul, R.4    Tazzari, P.L.5    Evangelisti, C.6
  • 44
    • 28844480101 scopus 로고    scopus 로고
    • mTOR regulates cell survival after etoposide treatment inprimary AML cells
    • Xu Q, Thompson JE, Carroll M. mTOR regulates cell survival after etoposide treatment inprimary AML cells. Blood 2005; 106: 4261-4268.
    • (2005) Blood , vol.106 , pp. 4261-4268
    • Xu, Q.1    Thompson, J.E.2    Carroll, M.3
  • 45
    • 33847225602 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts
    • Tazzari PL, Cappellini A, Ricci F, Evangelisti C, Papa V, Grafone T, et al. Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts. Leukemia 2007; 21: 427-438.
    • (2007) Leukemia , vol.21 , pp. 427-438
    • Tazzari, P.L.1    Cappellini, A.2    Ricci, F.3    Evangelisti, C.4    Papa, V.5    Grafone, T.6
  • 46
    • 34247578315 scopus 로고    scopus 로고
    • ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance
    • de Jonge-Peeters SD, Kuipers F, de Vries EG, Vellenga E. ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance. Crit Rev Oncol Hematol 2007; 62: 214-226.
    • (2007) Crit Rev Oncol Hematol , vol.62 , pp. 214-226
    • de Jonge-Peeters, S.D.1    Kuipers, F.2    de Vries, E.G.3    Vellenga, E.4
  • 47
    • 0038121035 scopus 로고    scopus 로고
    • Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses
    • Li HY, Appelbaum FR, Willman CL, Zager RA, Banker DE. Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood 2003; 101: 3628-3634.
    • (2003) Blood , vol.101 , pp. 3628-3634
    • Li, H.Y.1    Appelbaum, F.R.2    Willman, C.L.3    Zager, R.A.4    Banker, D.E.5
  • 48
    • 34250732230 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential
    • Cheung AM, Wan TS, Leung JC, Chan LY, Huang H, Kwong YL, et al. Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential. Leukemia 2007; 21: 1423-1430.
    • (2007) Leukemia , vol.21 , pp. 1423-1430
    • Cheung, A.M.1    Wan, T.S.2    Leung, J.C.3    Chan, L.Y.4    Huang, H.5    Kwong, Y.L.6
  • 49
    • 0037606054 scopus 로고    scopus 로고
    • Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML)
    • Guan Y, Gerhard B, Hogge DE. Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML). Blood 2003; 101: 3142-3149.
    • (2003) Blood , vol.101 , pp. 3142-3149
    • Guan, Y.1    Gerhard, B.2    Hogge, D.E.3
  • 51
    • 0036040031 scopus 로고    scopus 로고
    • The anti-apoptotic genes Bcl-X-L and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells
    • Konopleva M, Zhao SR, Hu W, Jiang SW, Snell V, Weidner D, et al. The anti-apoptotic genes Bcl-X-L and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells. Br J Haematol 2002; 118: 521-534.
    • (2002) Br J Haematol , vol.118 , pp. 521-534
    • Konopleva, M.1    Zhao, S.R.2    Hu, W.3    Jiang, S.W.4    Snell, V.5    Weidner, D.6
  • 52
    • 0031655802 scopus 로고    scopus 로고
    • Multistep nature of metastatic inefficiency: Dormancy of solitary cells after successful extravasation and limited survival of early micrometastases
    • Luzzi KJ, MacDonald IC, Schmidt EE, Kerkvliet N, Morris VL, Chambers AF, et al. Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. Am J Pathol 1998; 153: 865-873.
    • (1998) Am J Pathol , vol.153 , pp. 865-873
    • Luzzi, K.J.1    Macdonald, I.C.2    Schmidt, E.E.3    Kerkvliet, N.4    Morris, V.L.5    Chambers, A.F.6
  • 53
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • Balic M, Lin H, Young L, Hawes D, Giuliano A, McNamara G, et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res 2006; 12: 5615-5621.
    • (2006) Clin Cancer Res , vol.12 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6
  • 54
    • 58749108476 scopus 로고    scopus 로고
    • A novel mouse model of human breast cancer stem-like cells with high CD44+CD24-/lower phenotype metastasis to human bone
    • Ling LJ, Wang S, Liu XA, Shen EC, Ding Q, Lu C, et al. A novel mouse model of human breast cancer stem-like cells with high CD44+CD24-/lower phenotype metastasis to human bone. Chin Med J 2008; 121: 1980-1986.
    • (2008) Chin Med J , vol.121 , pp. 1980-1986
    • Ling, L.J.1    Wang, S.2    Liu, X.A.3    Shen, E.C.4    Ding, Q.5    Lu, C.6
  • 55
    • 43249101948 scopus 로고    scopus 로고
    • Stem-cell ecology and stem cells in motion
    • Papayannopoulou T, Scadden DT. Stem-cell ecology and stem cells in motion. Blood 2008; 111: 3923-3930.
    • (2008) Blood , vol.111 , pp. 3923-3930
    • Papayannopoulou, T.1    Scadden, D.T.2
  • 56
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003; 425: 836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4    He, X.5    Tong, W.G.6
  • 58
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005; 121: 1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 59
    • 33646435309 scopus 로고    scopus 로고
    • The stem cell niches in bone
    • Yin T, Li LH. The stem cell niches in bone. J Clin Invest 2006; 116: 1195-1201.
    • (2006) J Clin Invest , vol.116 , pp. 1195-1201
    • Yin, T.1    Li, L.H.2
  • 60
    • 33847227974 scopus 로고    scopus 로고
    • The stem cell niche in health and leukemic disease
    • Scadden DT. The stem cell niche in health and leukemic disease. Best Pract Res Clin Haematol 2007; 20: 19-27.
    • (2007) Best Pract Res Clin Haematol , vol.20 , pp. 19-27
    • Scadden, D.T.1
  • 62
    • 34249281332 scopus 로고    scopus 로고
    • The cofilin pathway in breast cancer invasion and metastasis
    • Wang WG, Eddy R, Condeelis J. The cofilin pathway in breast cancer invasion and metastasis. Nat Rev Cancer 2007; 7: 429-444.
    • (2007) Nat Rev Cancer , vol.7 , pp. 429-444
    • Wang, W.G.1    Eddy, R.2    Condeelis, J.3
  • 63
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopietic bone marrow progenitors initiate the pre-metastatic niche
    • Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, et al. VEGFR1-positive haematopietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005; 438: 820-826.
    • (2005) Nature , vol.438 , pp. 820-826
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3    Bramley, A.H.4    Vincent, L.5    Costa, C.6
  • 64
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
    • Kucia M, Reca R, Miekus K, Wanzeck J, Wojakowski W, Janowska-Wieczorek A, et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 2005; 23: 879-894.
    • (2005) Stem Cells , vol.23 , pp. 879-894
    • Kucia, M.1    Reca, R.2    Miekus, K.3    Wanzeck, J.4    Wojakowski, W.5    Janowska-Wieczorek, A.6
  • 65
    • 33747109086 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer
    • Dewan MZ, Ahmed S, Iwasaki Y, Ohba K, Toi M, Yamamoto N. Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer. Biomed Pharmacother 2006; 60: 273-276.
    • (2006) Biomed Pharmacother , vol.60 , pp. 273-276
    • Dewan, M.Z.1    Ahmed, S.2    Iwasaki, Y.3    Ohba, K.4    Toi, M.5    Yamamoto, N.6
  • 66
    • 3042616145 scopus 로고    scopus 로고
    • Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
    • Liang Z, Wu T, Lou H, Yu X, Taichman RS, Lau SK, et al. Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res 2004; 64: 4302-4308.
    • (2004) Cancer Res , vol.64 , pp. 4302-4308
    • Liang, Z.1    Wu, T.2    Lou, H.3    Yu, X.4    Taichman, R.S.5    Lau, S.K.6
  • 67
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007; 1: 313-323.
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6
  • 68
    • 0037029654 scopus 로고    scopus 로고
    • Hematopoietic stem cells are uniquely selective in their migratory response to chemokines
    • Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL. Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med 2002; 195: 1145-1154.
    • (2002) J Exp Med , vol.195 , pp. 1145-1154
    • Wright, D.E.1    Bowman, E.P.2    Wagers, A.J.3    Butcher, E.C.4    Weissman, I.L.5
  • 69
    • 13744255245 scopus 로고    scopus 로고
    • CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice
    • Tavor S, Petit I, Porozov S, Avigdor A, Dar A, Leider-Trejo L, et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Res 2004; 64: 2817-2824.
    • (2004) Cancer Res , vol.64 , pp. 2817-2824
    • Tavor, S.1    Petit, I.2    Porozov, S.3    Avigdor, A.4    Dar, A.5    Leider-Trejo, L.6
  • 70
    • 25444473106 scopus 로고    scopus 로고
    • The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
    • Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, et al. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol 2005; 25: 8581-8591.
    • (2005) Mol Cell Biol , vol.25 , pp. 8581-8591
    • Pratap, J.1    Javed, A.2    Languino, L.R.3    van Wijnen, A.J.4    Stein, J.L.5    Stein, G.S.6
  • 71
    • 0242636591 scopus 로고    scopus 로고
    • IL-18 increases invasiveness of HL-60 myeloid leukemia cells: Up-regulation of matrix metalloproteinases-9 (MMP-9) expression
    • Zhang B, Wu KF, Cao ZY, Rao Q, Ma XT, Zheng GG, et al. IL-18 increases invasiveness of HL-60 myeloid leukemia cells: up-regulation of matrix metalloproteinases-9 (MMP-9) expression. Leuk Res 2004; 28: 91-95.
    • (2004) Leuk Res , vol.28 , pp. 91-95
    • Zhang, B.1    Wu, K.F.2    Cao, Z.Y.3    Rao, Q.4    Ma, X.T.5    Zheng, G.G.6
  • 72
    • 33750017080 scopus 로고    scopus 로고
    • MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha 4 beta 1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration
    • Redondo-Munoz J, Escobar-Diaz E, Samaniego R, Terol MJ, Garcia-Marco JA, Garcia-Pardo A. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha 4 beta 1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood 2006; 108: 3143-3151.
    • (2006) Blood , vol.108 , pp. 3143-3151
    • Redondo-Munoz, J.1    Escobar-Diaz, E.2    Samaniego, R.3    Terol, M.J.4    Garcia-Marco, J.A.5    Garcia-Pardo, A.6
  • 73
    • 43549115238 scopus 로고    scopus 로고
    • Cell-surface MMP-9 regulates the invasive capacity of leukemia blast cells with monocytic features
    • Paupert J, Mansat-De Mas V, Demur C, Salles B, Muller C. Cell-surface MMP-9 regulates the invasive capacity of leukemia blast cells with monocytic features. Cell Cycle 2008; 7: 1047-1053.
    • (2008) Cell Cycle , vol.7 , pp. 1047-1053
    • Paupert, J.1    Mansat-De mas, V.2    Demur, C.3    Salles, B.4    Muller, C.5
  • 74
    • 18444389451 scopus 로고    scopus 로고
    • Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
    • Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 2002; 109: 625-637.
    • (2002) Cell , vol.109 , pp. 625-637
    • Heissig, B.1    Hattori, K.2    Dias, S.3    Friedrich, M.4    Ferris, B.5    Hackett, N.R.6
  • 75
    • 85047690740 scopus 로고    scopus 로고
    • HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
    • Kollet O, Shivtiel S, Chen YQ, Suriawinata J, Thung SN, Dabeva MD, et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. J Clin Invest 2003; 112: 160-169.
    • (2003) J Clin Invest , vol.112 , pp. 160-169
    • Kollet, O.1    Shivtiel, S.2    Chen, Y.Q.3    Suriawinata, J.4    Thung, S.N.5    Dabeva, M.D.6
  • 77
    • 54349113632 scopus 로고    scopus 로고
    • Advance in hematopoietic stem cells transplantation for leukemia
    • Huang XJ. Advance in hematopoietic stem cells transplantation for leukemia. Chin Med J 2008; 121: 1763-1765.
    • (2008) Chin Med J , vol.121 , pp. 1763-1765
    • Huang, X.J.1
  • 79
    • 23144442823 scopus 로고    scopus 로고
    • CD33 as a target of therapy in acute myeloid leukemia: Current status and future perspectives
    • Sperr WR, Florian S, Hauswirth AW, Valent P. CD33 as a target of therapy in acute myeloid leukemia:current status and future perspectives. Leuk Lymphoma 2005; 46: 1115-1120.
    • (2005) Leuk Lymphoma , vol.46 , pp. 1115-1120
    • Sperr, W.R.1    Florian, S.2    Hauswirth, A.W.3    Valent, P.4
  • 80
    • 58249100053 scopus 로고    scopus 로고
    • CXCR4 antagonists: Targeting the microenvironment in leukemia and other cancers
    • Burger JA, Peled A. CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers. Leukemia 2009; 23: 43-52.
    • (2009) Leukemia , vol.23 , pp. 43-52
    • Burger, J.A.1    Peled, A.2
  • 81
    • 67649200331 scopus 로고    scopus 로고
    • Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells
    • Jin L, Lee EM, Ramshaw HS, Busfield SJ, Peoppl AG, Wilkinson L, et al. Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells. Cell Stem Cell 2009; 5: 31-42.
    • (2009) Cell Stem Cell , vol.5 , pp. 31-42
    • Jin, L.1    Lee, E.M.2    Ramshaw, H.S.3    Busfield, S.J.4    Peoppl, A.G.5    Wilkinson, L.6
  • 83
    • 34447634119 scopus 로고    scopus 로고
    • The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis
    • Hosen N, Shirakata T, Nishida S, Yanagihara M, Tsuboi A, Kawakami M, et al. The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis. Leukemia 2007; 21: 1783-1791.
    • (2007) Leukemia , vol.21 , pp. 1783-1791
    • Hosen, N.1    Shirakata, T.2    Nishida, S.3    Yanagihara, M.4    Tsuboi, A.5    Kawakami, M.6
  • 84
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-kappa B is constitutively activated in primitive human acute myelogenous leukemia cells
    • Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA, et al. Nuclear factor-kappa B is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001; 98: 2301-2307.
    • (2001) Blood , vol.98 , pp. 2301-2307
    • Guzman, M.L.1    Neering, S.J.2    Upchurch, D.3    Grimes, B.4    Howard, D.S.5    Rizzieri, D.A.6


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