A proton magnetic resonance spectroscopic study in juvenile absence epilepsy in early stages

European Journal of Paediatric Neurology

Volumn 14, Issue 3, 2010, Pages 224-228

  Kabay, Sibel Canbaz ^a   Gumustas, Oguzhan Guven ^b   Karaman, Handan Ozisik ^c   Ozden, Hilmi ^d   Erdinc, Oguz ^d  

^a DUMLUPINAR UNIVERSITY   (Turkey)

^b Burtom Emar Radiodiagnostic Center   (Turkey)

^c Onsekizmart University   (Turkey)

^d ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

Author keywords

Brain; Juvenile absence epilepsy; Proton magnetic resonance spectroscopy; Seizures

Indexed keywords

ABSENCE; ADOLESCENT; ADULT; ARTICLE; BRAIN REGION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ELECTROENCEPHALOGRAPHY; FEMALE; HUMAN; JUVENILE ABSENCE EPILEPSY; MALE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHOOL CHILD; SPIKE WAVE;

ADOLESCENT; ASPARTIC ACID; BRAIN; CHILD; CHOLINE; CREATINE; DISEASE PROGRESSION; DOWN-REGULATION; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; FEMALE; FRONTAL LOBE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMBRANE POTENTIALS; NEUROTOXINS; PREDICTIVE VALUE OF TESTS; THALAMUS;

EID: 77950867043     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2009.06.004     Document Type: Article

References (33)

1. Commission on Classification and Terminology of the International League against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 30 (1989) 389-399
2. Wolf P. Juvenile absence epilepsy. In: Roger J., Bureau M., Dravet C., Dreifuss F.E., Perret A., and Wolf P. (Eds). Epileptic syndromes in infancy, childhood and adolescence. 2nd ed. (1992), John Libbey, London 307-312
3. Gloor P., and Fariello R.G. Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy. Trends Neurosci 11 (1988) 63-68
4. Futatsugi Y., and Riviello J.J. Mechanisms of generalized absence epilepsy. Brain 20 (1998) 75-79
5. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. From the Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia 22 (1981) 489-501
6. Porter R.J. The absence epilepsies. Epilepsia 34 (1993) 42-48
7. Mattson R. Overview: idiopathic generalised epilepsies. Epilepsia 44 (2003) 2-6
8. Chan C.H., Briellmann R.S., Pell G.S., et al. Thalamic atrophy in childhood absence epilepsy. Epilepsia 47 (2006) 399-405
9. Hammen T., Stefan H., Ederhardt K., W-Huk B.H., and Tomandl B.F. Clinical applications of 1H-MR spectroscopy in the evaluation of epilepsies-what do pathological spectra stand for with regard to current results and what answers do they give to common clinical questions concerning the treatment of epilepsies?. Acta Neurol Scand 108 (2003) 223-238
10. Connelly A., Paesschen W.V., Porter D., et al. Proton magnetic resonance spectroscopy in MRI-negative temporal lobe epilepsy. Neurology 51 (1998) 61-66
11. Fojtiková D., Brázdil M., Horký J., et al. Magnetic resonance spectroscopy of the thalamus in patients with typical absence epilepsy. Seizure 15 (2006) 533-540
12. Branddao L.A., and Doningues R.C. MR spectroscopy of the brain (2003), Lippincott Williams & Wilkins, New York
13. Cendes F., Knowlton R.C., and Novotny E. Magnetic resonance spectroscopy in epilepsy: clinical issues. Epilepsia 43 (2002) 32-39
14. Cendes F., Stanley J.A., and Dubeau F. Proton magnetic resonance imaging for discrimination of absence and complex partial seizures. Ann Neurol 41 (1997) 74-80
15. Gadian D. N-Acetylaspartate and epilepsy. Magn Reson Imaging 13 (1995) 1193-1195
16. Li L.M., Dubeau F., Andermann F., and Arnold D.L. Proton magnetic resonance spectroscopic imaging studies in patients with newly diagnosed partial epilepsy. Epilepsia 41 (2000) 825-831
17. Labate A., Briellmann R.S., Abbott D.F., Waites A.B., and Graeme D. Jackson typical childhood absence seizures are associated with thalamic activation. Epileptic Disord 7 (2005) 373-377
18. Gloor P. Generalized cortico-reticular epilepsies: some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge. Epilepsia 9 (1968) 249-263
19. Steriade M., and Contreras D. Spike-wave complexes and fast components of cortically generated seizures, I: role of neocortex and thalamus. J Neurophysiol 80 (1998) 1439-1455
20. McCormick D.A., and Contreras D. On the cellular and network bases of epileptic seizures. Annu Rev Physiol 63 (2001) 815-846
21. McCormick D. Cortical and subcortical generators of normal and abnormal rhythmicity. Int Rev Neurobiol 49 (2002) 99-114
22. Dickson J.M., Wilkinson I.D., Howell S.J., Griffiths P.D., and Grünewald R.A. Idiopathic generalised epilepsy: a pilot study of memory and neuronal dysfunction in the temporal lobes, assessed by magnetic resonance spectroscopy. J Neurol Neurosurg Psychiatry 77 (2006) 834-840
23. Urenjak J., Williams S., Gadian D., and Noble B. Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 a, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro. J Neurochem 59 (1992) 55-61
24. Howe F., Maxwell R., Saunders S., Brown M.M., and Griffiths J.R. Proton spectroscopy in vivo. Magn Reson Q 9 (1993) 31-59
25. Stefanovic B., Warnking J.M., and Pike G.B. Hemodynamic and metabolic responses to neuronal inhibition. Neuroimage 22 (2004) 771-778
26. Bernasconi A., Bernasconi N., Natsume J., Antel S.B., Andermann F., and Arnold D.L. Magnetic resonance spectroscopy and imaging of the thalamus in idiopathic generalized epilepsy. Brain 126 (2003) 2447-2454
27. Salek-Haddadi A., Lemieux L., Merschhemke M., et al. Functional magnetic resonance imaging of human absence seizures. Ann Neurol 53 (2003) 663-667
28. Aghakhani Y., Bagshaw A.P., Benar C.G., et al. fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain 127 (2004) 1127-1144
29. Prevett M.C., Duncan J.S., Jones T., Fish D.R., and Brooks D.J. Demonstration of thalamic activation during typical absence seizures using H2 (15) O and PET. Neurology 45 (1995) 1396-1402
30. Nehlig A., Valenti M.P., Thiriaux A., et al. Ictal and interictal perfusion variations measured by SISCOM analysis in typical childhood absence seizures. Epileptic Disord 6 (2004) 247-253
31. Archer J.S., Abbott D.F., Waites A.B., and Jackson G.D. fMRI "deactivation" of the posterior cingulate during generalised spike and wave. Neuroimage 20 (2003) 1915-1929
32. Meencke H. Neuron density in the molecular layer of the frontal cortex in primary generalised epilepsy. Epilepsia 26 (1985) 450
33. Woermann F., Free S., Koepp M., Sisodiya S.M., and Duncan J.S. Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI. Brain 122 (1999) 2101-2108