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Volumn 66, Issue 1, 2010, Pages 46-50

Age-related macular degeneration: Current and novel therapies

Author keywords

Antioxidant; Exudative; Macular degeneration; Neuroprotection; Nonexudative; Treatment; VEGF; Vitamin

Indexed keywords

ANTIOXIDANT; BEVACIZUMAB; PEGAPTANIB; RANIBIZUMAB; VERTEPORFIN;

EID: 77950866700     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2010.02.006     Document Type: Review
Times cited : (42)

References (32)
  • 1
    • 0026681119 scopus 로고
    • Prevalence of age-related maculopathy. The Beaver Dam Eye Study
    • Klein B.E., and Linton K.L. Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology 99 6 (1992) 933-943
    • (1992) Ophthalmology , vol.99 , Issue.6 , pp. 933-943
    • Klein, B.E.1    Linton, K.L.2
  • 2
    • 11144354339 scopus 로고    scopus 로고
    • Prevalence of age-related macular degeneration in the United States
    • Friedman D.S., O'Colmain B.J., Munoz B., et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 122 4 (2004) 564-572
    • (2004) Arch Ophthalmol , vol.122 , Issue.4 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Munoz, B.3
  • 3
    • 0031602252 scopus 로고    scopus 로고
    • A global initiative for the elimination of avoidable blindness
    • Thylefors B. A global initiative for the elimination of avoidable blindness. Am J Ophthalmol 125 1 (1998) 90-93
    • (1998) Am J Ophthalmol , vol.125 , Issue.1 , pp. 90-93
    • Thylefors, B.1
  • 4
    • 0037230255 scopus 로고    scopus 로고
    • Quality of life with macular degeneration: perceptions of patients, clinicians, and community members
    • Stein J.D., Brown M.M., Brown G.C., et al. Quality of life with macular degeneration: perceptions of patients, clinicians, and community members. Br J Ophthalmol 87 (2003) 8-12
    • (2003) Br J Ophthalmol , vol.87 , pp. 8-12
    • Stein, J.D.1    Brown, M.M.2    Brown, G.C.3
  • 6
    • 0032438352 scopus 로고    scopus 로고
    • Genetic risk of age-related maculopathy. Population-based familial aggregation study
    • Klaver C.C., Wolfs R.C., Assink J.J., et al. Genetic risk of age-related maculopathy. Population-based familial aggregation study. Arch Ophthalmol 116 1 (1998) 1646-1651
    • (1998) Arch Ophthalmol , vol.116 , Issue.1 , pp. 1646-1651
    • Klaver, C.C.1    Wolfs, R.C.2    Assink, J.J.3
  • 7
    • 0032786405 scopus 로고    scopus 로고
    • Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with age-related macular degeneration and histologic examination of surgically excised choroidal neovascular membranes
    • Spraul C.W., Lang G.E., Grossniklaus H.E., et al. Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with age-related macular degeneration and histologic examination of surgically excised choroidal neovascular membranes. Surv Ophthalmol 44 (1999) S10-S32
    • (1999) Surv Ophthalmol , vol.44
    • Spraul, C.W.1    Lang, G.E.2    Grossniklaus, H.E.3
  • 8
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001;119:1416-36.
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001;119:1416-36.
  • 9
    • 34249824136 scopus 로고    scopus 로고
    • Age-Related Eye Disease Study Research Group. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11
    • Bressler N.M., Bressler S.B., Congdon N.G., et al. Age-Related Eye Disease Study Research Group. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Arch Ophthalmol 121 (2003) 1621-1624
    • (2003) Arch Ophthalmol , vol.121 , pp. 1621-1624
    • Bressler, N.M.1    Bressler, S.B.2    Congdon, N.G.3
  • 10
    • 30944437438 scopus 로고    scopus 로고
    • Smoking and age-related macular degeneration: a review of association
    • Thornton J., Edwards R., Mitchell P., et al. Smoking and age-related macular degeneration: a review of association. Eye 19 (2005) 935-944
    • (2005) Eye , vol.19 , pp. 935-944
    • Thornton, J.1    Edwards, R.2    Mitchell, P.3
  • 11
    • 0026439413 scopus 로고    scopus 로고
    • Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group. Arch Ophthalmol 1992;110:1701-8.
    • Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group. Arch Ophthalmol 1992;110:1701-8.
  • 12
    • 0344305692 scopus 로고    scopus 로고
    • Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts and fish intake
    • Seddon J.M., Cote J., and Rosner B. Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts and fish intake. Arch Ophthalmol 121 (2003) 1728-1737
    • (2003) Arch Ophthalmol , vol.121 , pp. 1728-1737
    • Seddon, J.M.1    Cote, J.2    Rosner, B.3
  • 13
    • 0038107065 scopus 로고    scopus 로고
    • Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor
    • Zhang C., Baffi J., Cousins S.W., et al. Oxidant-induced cell death in retinal pigment epithelium cells mediated through the release of apoptosis-inducing factor. J Cell Sci 116 (2003) 1915-1923
    • (2003) J Cell Sci , vol.116 , pp. 1915-1923
    • Zhang, C.1    Baffi, J.2    Cousins, S.W.3
  • 14
    • 68949092354 scopus 로고    scopus 로고
    • Randomized double-blind 2 × 2 trial of low-dose tamoxifen and fenretinide for breast cancer prevention in high-risk premenopausal women
    • Decensi A., Robertson C., Guerrieri-Gonzaga A., et al. Randomized double-blind 2 × 2 trial of low-dose tamoxifen and fenretinide for breast cancer prevention in high-risk premenopausal women. J Clin Oncol 27 August (23) (2009) 3749-3756
    • (2009) J Clin Oncol , vol.27 , Issue.August 23 , pp. 3749-3756
    • Decensi, A.1    Robertson, C.2    Guerrieri-Gonzaga, A.3
  • 15
    • 34248587416 scopus 로고    scopus 로고
    • New therapeutic targets in atrophic age-related macular degeneration
    • Petrukhin K. New therapeutic targets in atrophic age-related macular degeneration. Expert Opin Ther Targets 11 5 (2007) 625-639
    • (2007) Expert Opin Ther Targets , vol.11 , Issue.5 , pp. 625-639
    • Petrukhin, K.1
  • 16
    • 35448975681 scopus 로고    scopus 로고
    • Progress in defining the molecular biology of age related macular degeneration
    • Lotery A., and Trump D. Progress in defining the molecular biology of age related macular degeneration. Hum Genet 122 November (3-4) (2007) 219-236
    • (2007) Hum Genet , vol.122 , Issue.November 3-4 , pp. 219-236
    • Lotery, A.1    Trump, D.2
  • 17
    • 77950866441 scopus 로고    scopus 로고
    • Complement C3 inhibitor POT-4: pre-clinical safety of intra-vitreal and systemic administration
    • The Retina Society, Boston, September
    • Slakter J.S. Complement C3 inhibitor POT-4: pre-clinical safety of intra-vitreal and systemic administration. Oral presentation. The Retina Society, Boston, September (2007)
    • (2007) Oral presentation
    • Slakter, J.S.1
  • 18
    • 53249147453 scopus 로고    scopus 로고
    • NT-501: an ophthalmic implant of polymer-encapsulated ciliary neurotrophic factor-producing cells
    • Emerich D.F., and Thanos C.G. NT-501: an ophthalmic implant of polymer-encapsulated ciliary neurotrophic factor-producing cells. Curr Opin Mol Ther 10 October (5) (2008) 506-515
    • (2008) Curr Opin Mol Ther , vol.10 , Issue.October 5 , pp. 506-515
    • Emerich, D.F.1    Thanos, C.G.2
  • 19
    • 6944253464 scopus 로고    scopus 로고
    • Outcome after transplantation of autologous RPE in age related macular degeneration-a prospective trial
    • Binder S., Krebs I., Hilgrers H.D., et al. Outcome after transplantation of autologous RPE in age related macular degeneration-a prospective trial. Invest Ophthalmol Vis Sci 45 (2004) 4151-4160
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 4151-4160
    • Binder, S.1    Krebs, I.2    Hilgrers, H.D.3
  • 20
    • 0036756904 scopus 로고    scopus 로고
    • Gene therapy for genetic and acquired retinal disease
    • Chaum E., and Hatton M.P. Gene therapy for genetic and acquired retinal disease. Surv Ophthalmol 47 (2002) 449-469
    • (2002) Surv Ophthalmol , vol.47 , pp. 449-469
    • Chaum, E.1    Hatton, M.P.2
  • 21
    • 0026409933 scopus 로고
    • Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials
    • Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group. Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials. Arch Ophthalmol 109 (1991) 1109-1114
    • (1991) Arch Ophthalmol , vol.109 , pp. 1109-1114
  • 22
    • 0035009086 scopus 로고    scopus 로고
    • Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: Two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization-verteporfin in photodynamic therapy
    • Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization-verteporfin in photodynamic therapy report 2. Am J Ophthalmol 2001;131:541-60.
    • (2001) Am J Ophthalmol , vol.131 , pp. 541-560
  • 23
    • 0342632445 scopus 로고    scopus 로고
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials-Tap Report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol 1999;117:1329-45
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials-Tap Report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol 1999;117:1329-45.
  • 25
    • 33749445317 scopus 로고    scopus 로고
    • MARINA Study Group. Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld P.J., Brown D.M., Heier J.S., et al. MARINA Study Group. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 355 14 (2006) 1419-1431
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 26
    • 33749451356 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin for neovascular age-related macular degeneration
    • Brown D.M., Kaiser P.K., Michels M., et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 355 (2006) 1432-1444
    • (2006) N Engl J Med , vol.355 , pp. 1432-1444
    • Brown, D.M.1    Kaiser, P.K.2    Michels, M.3
  • 27
    • 0029781944 scopus 로고    scopus 로고
    • Variations in the clinical course of submacular hemorrhage
    • Berrocal M.H., Lewis M.L., and Flynn H.W. Variations in the clinical course of submacular hemorrhage. Am J Ophthalmol 122 (1996) 486-493
    • (1996) Am J Ophthalmol , vol.122 , pp. 486-493
    • Berrocal, M.H.1    Lewis, M.L.2    Flynn, H.W.3
  • 28
    • 0034994210 scopus 로고    scopus 로고
    • Treatment of subretinal hemorrhage with tissue plasminogen activator
    • Borillo J.L., and Regillo C.D. Treatment of subretinal hemorrhage with tissue plasminogen activator. Curr Opin Ophthalmol 12 (2001) 207-211
    • (2001) Curr Opin Ophthalmol , vol.12 , pp. 207-211
    • Borillo, J.L.1    Regillo, C.D.2
  • 29
    • 7444227954 scopus 로고    scopus 로고
    • Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: ophthalmic findings: SST report no. 11
    • Submacular Surgery Trials (SST) Research Group. Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: ophthalmic findings: SST report no. 11. Ophthalmology 111 11 (2004) 1967-1980
    • (2004) Ophthalmology , vol.111 , Issue.11 , pp. 1967-1980
    • Submacular Surgery Trials (SST) Research Group1
  • 30
    • 33947657878 scopus 로고    scopus 로고
    • The end of submacular surgery for age-related macular degeneration? A meta-analysis
    • Falkner C.I., Leitich H., Frommlet F., et al. The end of submacular surgery for age-related macular degeneration? A meta-analysis. Graefes Arch Clin Exp Ophthalmol 245 4 (2007) 490-501
    • (2007) Graefes Arch Clin Exp Ophthalmol , vol.245 , Issue.4 , pp. 490-501
    • Falkner, C.I.1    Leitich, H.2    Frommlet, F.3
  • 31
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • Reich S.J., Fosnot J., Kuoki A., et al. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 9 (2003) 210-216
    • (2003) Mol Vis , vol.9 , pp. 210-216
    • Reich, S.J.1    Fosnot, J.2    Kuoki, A.3
  • 32
    • 0037143764 scopus 로고    scopus 로고
    • VEGF-Trap: a VEGF blocker with potent antitumor effects
    • Holash J., Davis S., Papdopoulos N., et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci USA 99 17 (2002) 11393-11398
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.17 , pp. 11393-11398
    • Holash, J.1    Davis, S.2    Papdopoulos, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.