Crystal structure and comparative functional analyses of a Mycobacterium Aldo-Keto reductase

Journal of Molecular Biology

Volumn 398, Issue 1, 2010, Pages 26-39

  Scoble, Judith ^a   McAlister, Adrian D ^a   Fulton, Zara ^a   Troy, Sally ^a   Byres, Emma ^a   Vivian, Julian P ^a   Brammananth, Rajini ^a   Wilce, Matthew C J ^a   Le Nours, Jérôme ^a   Zaker Tabrizi, Leyla ^a   Coppel, Ross L ^a   Crellin, Paul K ^a   Rossjohn, Jamie ^a   Beddoe, Travis ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Aldo keto reductase; Isoniazid; Mycobacterium; NADPH dependent enzyme

Indexed keywords

ALDO KETO REDUCTASE 5H1; BACTERIAL ENZYME; ISONIAZID; OXIDOREDUCTASE; PROTEIN RV2971; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME STRUCTURE; HYDROLYSIS; MYCOBACTERIUM; PRIORITY JOURNAL; PROTEIN FOLDING;

BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 77950858807     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.02.021     Document Type: Article

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