Fractional flow reserve: An indispensable diagnostic tool in the Cardiac Catheterisation Laboratory

Hellenic Journal of Cardiology

Volumn 51, Issue 2, 2010, Pages 133-141

  Hamilos, Michalis ^a   Peace, Aaron ^b   Kochiadakis, George ^a   Skalidis, Emmanuel ^a   Ntalianis, Argirios ^b   De Bruyne, Bernard ^b   Vardas, Panos ^a  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^b CARDIOVASCULAR CENTER   (Belgium)

Author keywords

Coronary angiography; Coronary atherosclerosis; Fractional flow reserve

Indexed keywords

ADENOSINE; ANTICOAGULANT AGENT; CONTRAST MEDIUM; HEPARIN; ISOSORBIDE DINITRATE; PAPAVERINE;

ACUTE CORONARY SYNDROME; ANGIOCARDIOGRAPHY; ANTICOAGULATION; BLOOD PRESSURE; CATHETER; CLINICAL ASSESSMENT TOOL; CLINICAL TRIAL; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY OBSTRUCTION; CORONARY ARTERY PRESSURE; CORONARY FLOW RESERVE; CORONARY STENT; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DISEASE SEVERITY; DRUG ELUTING STENT; FRACTIONAL FLOW RESERVE; HEART CATHETERIZATION; HEART INFARCTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; HEART MUSCLE REVASCULARIZATION; HEART OUTPUT; HEART RATE; HUMAN; HYPEREMIA; INTRACORONARY INFUSION; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; REVIEW; SENSITIVITY AND SPECIFICITY; STENT THROMBOSIS; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT OUTCOME; VASCULAR DISEASE; VASCULAR RESISTANCE; VASODILATATION;

BLOOD FLOW VELOCITY; CARDIAC CARE FACILITIES; CORONARY DISEASE; FRACTIONAL FLOW RESERVE, MYOCARDIAL; HEART CATHETERIZATION; HEMORHEOLOGY; HUMANS; LABORATORIES, HOSPITAL; VASCULAR RESISTANCE;

EID: 77950848912     PISSN: 10117970     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (53)

1. Topol EJ, Ellis SG, Cosgrove DM, et al. Analysis of coronary angioplasty practice in the United States with an insuranceclaims data base. Circulation. 1993; 87: 1489-1497.
2. Fisher LD, Judkins MP, Lesperance J, et al. Reproducibility of coronary arteriographic reading in the coronary artery surgery study (CASS). Cathet Cardiovasc Diagn. 1982; 8: 565-575. (Pubitemid 13170436)
3. Gould KL. Percent coronary stenosis: battered gold standard, pernicious relic or clinical practicality? J Am Coll Cardiol. 1988; 11: 886-888.
4. Seiler C, Kirkeeide RL, Gould KL. Basic structure-function relations of the epicardial coronary vascular tree. Basis of quantitative coronary arteriography for diffuse coronary artery disease. Circulation. 1992; 85: 1987-2003.
5. Gould KL, Lipscomb K, Hamilton GW. Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve. Am J Cardiol. 1974; 33: 87-94.
6. Kern MJ, Lerman A, Bech J-W, et al. Physiological assessment of coronary artery disease in the cardiac catheterization laboratory: a scientific statement from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology. Circulation. 2006; 114: 1321-1341.
7. Johnson PC. Autoregulation of blood flow. Circ Res. 1986; 59: 483.
8. Young MA, Vatner SF. Regulation of large coronary arteries. Circ Res. 1986; 59: 579.
9. Martin SE, Lenhard SD, Schmarkey LS, Offenbacher S, Odle BM. Adenosine regulates coronary blood flow during increased work and decreased supply. Am J Physiol. 1993; 264: H1438-46.
10. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980; 288: 373-376.
11. Chilian WM, Marcus ML. Effects of coronary and extravascular pressure on intramyocardial and epicardial blood velocity. Am J Physiol. 1985; 248: H170-8.
12. Austin RE Jr, Smedira NG, Squiers TM, Hoffman JL. Influence of cardiac contraction and coronary vasomotor tone on regional myocardial blood flow. Am J Physiol. 1994; 266: H2542-53.
13. McGinn AL, Wilson RF, Olivari MT, Homans DC, White CW. Coronary vasodilator reserve after human orthotopic cardiac transplantation. Circulation. 1988; 78: 1200-1209.
14. Erbel R, Ge J, Bockisch A, et al. Value of intracoronary ultrasound and Doppler in the differentiation of angiographically normal coronary arteries: a prospective study in patients with angina pectoris. Eur Heart J. 1996; 17: 880-889. (Pubitemid 26187177)
15. Gould KL, Kirkeeide RL, Buchi M. Coronary flow reserve as a physiologic measure of stenosis severity. J Am Coll Cardiol. 1990; 15: 459-474. (Pubitemid 20067508)
16. Fearon WF, Balsam LB, Farouque HMO, et al. Novel index for invasively assessing the coronary microcirculation. Circulation. 2003; 107: 3129-3132.
17. Fearon WF, Shah M, Ng M, et al. Predictive value of the index of microcirculatory resistance in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2008; 51: 560-565.
18. Sezer M, Oflaz H, Gören T, et al. Intracoronary streptokinase after primary percutaneous coronary intervention. N Engl J Med. 2007; 356: 1823-1834. (Pubitemid 46698463)
19. Melikian N, Vercauteren S, Fearon W, et al. Quantitative assessment of microvascular function in normal subjects and in patients with epicardial coronary atherosclerosis. Eurointervention. 2010, in press.
20. Pijls NH, van Son JA, Kirkeeide RL, De Bruyne B, Gould KL. Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty. Circulation. 1993; 87: 1354-1367. (Pubitemid 23110406)
21. de Bruyne B, Bartunek J, Sys SU, Pijls NH, Heyndrickx GR, Wijns W. Simultaneous coronary pressure and flow velocity measurements in humans. Feasibility, reproducibility, and hemodynamic dependence of coronary flow velocity reserve, hyperemic flow versus pressure slope index, and fractional flow reserve. Circulation. 1996; 94: 1842-1849.
22. Legalery P, Seronde M-F, Meneveau N, Schiele F, Bassand J-P. Measuring pressure-derived fractional flow reserve through four French diagnostic catheters. Am J Cardiol. 2003; 91: 1075-1078. (Pubitemid 36514922)
23. De Bruyne B, Pijls NH, Barbato E, et al. Intracoronary and intravenous adenosine 5'-triphosphate, adenosine, papaverine, and contrast medium to assess fractional flow reserve in humans. Circulation. 2003; 107: 1877-1883. (Pubitemid 36444128)
24. McGeoch RJ, Oldroyd KG. Pharmacological options for inducing maximal hyperaemia during studies of coronary physiology. Catheter Cardiovasc Interv. 2008; 71: 198-204.
25. De Bruyne B, Baudhuin T, Melin JA, et al. Coronary flow reserve calculated from pressure measurements in humans. Validation with positron emission tomography. Circulation. 1994; 89: 1013-1022.
26. Pijls NH, Van Gelder B, Van der Voort P et al. Fractional flow reserve. A useful index to evaluate the influence of an epicardial coronary stenosis on myocardial blood flow. Circulation. 1995; 92: 3183-3193.
27. Pijls NH, De Bruyne B, Peels K, et al. Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses. N Engl J Med. 1996; 334: 1703-1708. (Pubitemid 26193622)
28. De Bruyne B, Sarma J. Fractional flow reserve: a review. Heart. 2008; 94: 949-959.
29. Wijns W, De Bruyne B, Vanhoenacker PK. What does the clinical cardiologist need from noninvasive cardiac imaging: is it time to adjust practices to meet evolving demands? J Nucl Cardiol. 2007: 366-370.
30. Fard-Esfahani A, Assadi M, Saghari M, et al. The role of myocardial perfusion imaging in the evaluation of patients undergoing percutaneous transluminal coronary angioplasty. Hellenic J Cardiol. 2009; 50: 396-401.
31. Bech GJ, De Bruyne B, Pijls NH, et al. Fractional flow reserve to determine the appropriateness of angioplasty in moderate coronary stenosis: a randomized trial. Circulation. 2001; 103: 2928-2934. (Pubitemid 32578130)
32. Pijls NHJ, van Schaardenburgh P, Manoharan G, et al. Per- cutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study. J Am Coll Cardiol. 2007; 49: 2105-2111. (Pubitemid 46771047)
33. Lindstaedt M, Spiecker M, Perings C, et al. How good are experienced interventional cardiologists at predicting the functional significance of intermediate or equivocal left main coronary artery stenoses? Int J Cardiol. 2007; 120: 254-261.
34. Bech GJ, Droste H, Pijls NH, et al. Value of fractional flow reserve in making decisions about bypass surgery for equivocal left main coronary artery disease. Heart. 2001; 86: 547-552. (Pubitemid 32999868)
35. Lindstaedt M, Yazar A, Germing A, et al. Clinical outcome in patients with intermediate or equivocal left main coronary artery disease after deferral of surgical revascularization on the basis of fractional flow reserve measurements. Am Heart J. 2006; 152: 156.e1-9
36. Legutko J, Dudek D, Rzeszutko L, Wizimirski M, Dubiel JS. Fractional flow reserve assessment to determine the indications for myocardial revascularisation in patients with borderline stenosis of the left main coronary artery. Kardiol Pol. 2005; 63: 499-506. (Pubitemid 44283985)
37. Suemaru S, Iwasaki K, Yamamoto K, et al. Coronary pres- sure measurement to determine treatment strategy for equivocal left main coronary artery lesions. Heart Vessels. 2005; 20: 271-277. (Pubitemid 43013217)
38. Hamilos M, Muller O, Cuisset T, et al. Long-term clinical outcome after fractional flow reserve-guided treatment in patients with angiographically equivocal left main coronary artery stenosis. Circulation. 2009; 120: 1505-1512.
39. Lima RSL, Watson DD, Goode AR, et al. Incremental value of combined perfusion and function over perfusion alone by gated SPECT myocardial perfusion imaging for detection of severe three-vessel coronary artery disease. J Am Coll Cardiol. 2003; 42: 64-70.
40. Ragosta M, Bishop AH, Lipson LC, et al. Comparison be- tween angiography and fractional flow reserve versus singlephoton emission computed tomographic myocardial perfusion imaging for determining lesion significance in patients with multivessel coronary disease. Am J Cardiol. 2007; 99: 896-902. (Pubitemid 46483275)
41. Tonino PAL, De Bruyne B, Pijls NHJ, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009; 360: 213-224.
42. De Bruyne B, Pijls NH, Bartunek J, et al. Fractional flow reserve in patients with prior myocardial infarction. Circulation. 2001; 104: 157-162. (Pubitemid 32655831)
43. Marques KM, Knaapen P, Boellaard R, Lammertsma AA, Westerhof N, Visser FC. Microvascular function in viable myocardium after chronic infarction does not influence fractional flow reserve measurements. J Nucl Med. 2007; 48: 1987-1992. (Pubitemid 350232307)
44. Beleslin B, Ostojic M, Djordjevic-Dikic A, et al. The value of fractional and coronary flow reserve in predicting myocardial recovery in patients with previous myocardial infarction. Eur Heart J. 2008; 29: 2617-2624.
45. De Bruyne B, Pijls NH, Heyndrickx GR, Hodeige D, Kirkeeide R, Gould KL. Pressure-derived fractional flow reserve to assess serial epicardial stenoses: theoretical basis and animal validation. Circulation. 2000; 101: 1840-1847.
46. De Bruyne B, Hersbach F, Pijls NH, et al. Abnormal epicar- dial coronary resistance in patients with diffuse atherosclerosis but "Normal" coronary angiography. Circulation. 2001; 104: 2401-2406.
47. Pijls NH, De Bruyne B, Bech GJ, et al. Coronary pressure measurement to assess the hemodynamic significance of serial stenoses within one coronary artery: validation in humans. Circulation. 2000; 102: 2371-2377.
48. Pijls NHJ, Klauss V, Siebert U, et al. Coronary pressure mea- surement after stenting predicts adverse events at follow-up: a multicenter registry. Circulation. 2002; 105: 2950-2954. (Pubitemid 34693825)
49. Koo B-K, Kang H-J, Youn T-J, et al. Physiologic assessment of jailed side branch lesions using fractional flow reserve. J Am Coll Cardiol. 2005; 46: 633-637.
50. Koo BK, Park KW, Kang HJ, et al. Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve. Eur Heart J. 2008; 29: 726-732.
51. Aqel R, Zoghbi GJ, Hage F, Dell'Italia L, Iskandrian AE. Hemodynamic evaluation of coronary artery bypass graft lesions using fractional flow reserve. Catheter Cardiovasc Interv. 2008; 72: 479-485.
52. Bugiardini R, Bairey Merz CN. Angina with "normal" coronary arteries: a changing philosophy. JAMA. 2005; 293: 477-484.
53. Lin GA, Dudley RA, Lucas FL, Malenka DJ, Vittinghoff E, Redberg RF. Frequency of stress testing to document ischemia prior to elective percutaneous coronary intervention. JAMA. 2008; 300: 1765-1773.