Chromatographic determination of radiochemical purity Replacement of ITLC SG;Chromatographische Bestimmung der radiochemischen Reinheit von RadiopharmakeAlternativen zu ITLC SG

NuklearMedizin

Volumn 49, Issue 2, 2010, Pages 73-77

  Wunderlich, G ^a   Herrling, P ^a   Zurn A ^b   Anders, P ^b   Kotzerke, J ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b ROTOP Pharmaka AG   (Germany)

Author keywords

99mtc; ITLC; Quality control; Radiochemical purity; Radiopharmaceuticals

Indexed keywords

ALBUMIN TC 99M COLLOID; AMERSCAN MDP; CARDIOTOP; CYSTEINE ETHYL ESTER TC 99M; GALLIUM 68; GRANULOZYT; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; IBRITUMOMAB TIUXETAN; INDIUM CHLORIDE IN 111; LUTETIUM 177; MACROALBUMON; MACROSALB TC 99M; MEDRONATE TECHNETIUM TC 99M; MERTIATIDE TC 99M; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MICROSPHERE TC 99M; MONOCLONAL ANTIBODY TC 99M; NANOCIS; NANOCOLL TC 99M; PENTETATE TECHNETIUM TC 99M; PENTETREOTIDE; PENTETREOTIDE IN 111; PERTECHNETIC ACID TC 99M; RADIOPHARMACEUTICAL AGENT; RHENIUM SULFIDE COLLOID TC 99M; ROTOP B 20; ROTOP DTPA; ROTOP MAG 3; ROTOP NEUROSPECT; SUCCIMER TC 99M; TECHNESCAN LYOMAA; TECHNESCAN MAG 3; TECHNETIUM 99M; TEKTROTYD; TETROFOSMIN TC 99M; UNCLASSIFIED DRUG; YTTRIUM 90;

ARTICLE; DRUG PURITY; DRUG QUALITY; QUALITY CONTROL; RADIOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

CHROMATOGRAPHY, THIN LAYER; GLASS; ORGANOPHOSPHORUS COMPOUNDS; RADIOISOTOPES; RADIOPHARMACEUTICALS; TECHNETIUM;

EID: 77950844752     PISSN: 00295566     EISSN: None     Source Type: Journal    
DOI: 10.3413/nukmed-0279     Document Type: Article

References (8)

1. 99mTc-pertechnetate. J Nucl Med 1974; 15: 266-269.
2. Brandau W. Guidelines for radiation protection in medicine - radiopharmaceutical quality control. German Society of Nuclear Medicine. Nuklearmedizin 1994; 33: 118-124.
3. 99mTc-EDDA-HYNIC-DPhel, Tyr3]-octreotide. Appl Radiat Isot 2006; 64: 194-200.
4. 68Ga-DOTATOC PET/CT examinations. Nuklearmedizin 2009; 48: 201-207.
5. Millar AM, Beattie, LA, Craig F, O'Brien LM. An evaluation of GMCF-SA as a replacement for ITLCSG when measuring the levels of radiochemical impurities in Tc radiopharmaceuticals by thinlayer chromatography. J Lab Comp Radiopharm 2009; 52: 538-542.
6. Theobald AE. Quality Control of Radiopharmaceuticals. In: Sampson CB (ed). Textbook of Radiopharmcy. Amsterdam: Gordon and Breach Science Publishers 1999; 145-185.
7. th ed. 2007. www.edqm.eu/enVThe-European- Pharmacopoeia-6th-Edition-681.
8. Richtlinie Strahlenschutz in der Medizin vom 22. April 2002. Hrsg. Bundesministerium für Umwelt, Naturschutz und Reaktorsicherheit. www.bmu.de/strahlenschutz/doc/5613.php.