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Volumn 148, Issue 1, 2010, Pages 11-21

2-Methoxyestradiol induces morpho-functional changes and impairs the microtubular system in mouse neuroblastoma and rat glioma cells

Author keywords

2 Methoxyestradiol; C1300 Neuroblastoma cells; C6 Glioma cells; Tubulin

Indexed keywords

2 METHOXYESTRADIOL; 2-METHOXYESTRADIOL; DRUG DERIVATIVE; ESTRADIOL; TUBULIN; TUBULIN MODULATOR;

EID: 77950844371     PISSN: 00039829     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (33)
  • 1
    • 0345258488 scopus 로고    scopus 로고
    • 2 on Proliferative Cells
    • Banerjee S.N., Sengupta K., Banerjee S., Saxena N.K., Banerjee S.K. 2-Methoxyestradiol exhibits a bipha- sic effect on VEGF-A in tumour cells and upregula- tion is mediated through ER-alpha: a possible signaling pathway associated with the impact of 2-ME2 on proliferative cells. Neoplasia, 5: 417-426, 2003. (Pubitemid 37475650)
    • (2003) Neoplasia , vol.5 , Issue.5 , pp. 417-426
    • Banerjee, S.N.1    Sengupta, K.2    Banerjee, S.3    Saxena, N.K.4    Banerjee, S.K.5
  • 3
    • 0024376552 scopus 로고
    • Inhibition of rat liver microsomal estrogen 2-hydroxylase by 2-methoxyestrogens
    • DOI 10.1016/0022-4731(89)90045-9
    • Brueggemeier R.W. and Singh U. Inhibition of rat liver microsomal estrogen 2-hydroxylase by 2-methoxyestrogens. J. Steroid Biochem., 33: 589-593, 1989. (Pubitemid 19255732)
    • (1989) Journal of Steroid Biochemistry , vol.33 , Issue.4 A , pp. 589-593
    • Brueggemeier, R.W.1    Singh, U.2
  • 5
    • 33646390930 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estra- diol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phos-phorylation Bcl-2
    • Bu S.Z., Huang Q., Jiang Y.M., Min H.B., Hou Y., Guo Z.Y., Wei J.F., Wang J.W., Ni X., Zheng S.S. p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estra- diol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phos-phorylation Bcl-2. Apoptosis, 11: 413-425, 2006.
    • (2006) Apoptosis , vol.11 , pp. 413-425
    • Bu, S.Z.1    Huang, Q.2    Jiang, Y.M.3    Min, H.B.4    Hou, Y.5    Guo, Z.Y.6    Wei, J.F.7    Wang, J.W.8    Ni, X.9    Zheng, S.S.10
  • 6
    • 21244482124 scopus 로고    scopus 로고
    • Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton
    • DOI 10.1007/s11060-004-2158-4
    • Chamaon K., Stojek J., Kanakis D., Braeuninger S., Kirches E., Krause G., Mawrin C., Dietzmann K. Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton. J. Neurooncol., 72: 11-26, 2005. (Pubitemid 41149171)
    • (2005) Journal of Neuro-Oncology , vol.72 , Issue.1 , pp. 11-16
    • Chamaon, K.1    Stojek, J.2    Kanakis, D.3    Braeuninger, S.4    Kirches, E.5    Krause, G.6    Mawrin, C.7    Dietzmann, K.8
  • 7
    • 0033959187 scopus 로고    scopus 로고
    • Tubulin carboxypepti- dase/microtubules association can be detected in the distal region of neuronal processes
    • Contin M.A. and Arce C.A. Tubulin carboxypepti- dase/microtubules association can be detected in the distal region of neuronal processes. Neurochem. Res., 25: 27-36, 2000.
    • (2000) Neurochem. Res. , vol.25 , pp. 27-36
    • Contin, M.A.1    Arce, C.A.2
  • 8
    • 0025899234 scopus 로고
    • Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in cultures
    • Cory A.H., Owen T.C., Barltrop J.A., Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in cultures. Cancer Commun., 3: 207-212, 1991.
    • (1991) Cancer Commun , vol.3 , pp. 207-212
    • Cory, A.H.1    Owen, T.C.2    Barltrop, J.A.3    Cory, J.G.4
  • 11
    • 0023371190 scopus 로고
    • Postpolymerization, detyrosination of a-tubulin: A mechanism for subcellular differenziation of microtubules
    • Gundersen G.G., Khawaja S., Bulinski J.C. Postpolymerization, detyrosination of a-tubulin: a mechanism for subcellular differenziation of microtubules. J. Cell Biol., 105: 251-264, 1987.
    • (1987) J. Cell Biol. , vol.105 , pp. 251-264
    • Gundersen, G.G.1    Khawaja, S.2    Bulinski, J.C.3
  • 12
    • 0030069601 scopus 로고    scopus 로고
    • Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers
    • DOI 10.1021/bi951559s
    • Hamel E., Lin C.M., Flynn E., D'Amato R.J. Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubu- lin and with tubulin polymers. Biochemistry, 35: 1304-1310, 1996. (Pubitemid 26050794)
    • (1996) Biochemistry , vol.35 , Issue.4 , pp. 1304-1310
    • Hamel, E.1    Lin, C.M.2    Flynn, E.3    D'Amato, R.J.4
  • 13
    • 0034699513 scopus 로고    scopus 로고
    • Superoxide dismutase as a target for selective killing of cancer cells
    • Huang P., Feng L., Oldham E.A., Keating M.J., Plunkett W. Superoxide dismutase as a target for selective killing of cancer cells. Nature, 407: 309-395, 2000.
    • (2000) Nature , vol.407 , pp. 309-395
    • Huang, P.1    Feng, L.2    Oldham, E.A.3    Keating, M.J.4    Plunkett, W.5
  • 15
    • 33749578369 scopus 로고    scopus 로고
    • 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules
    • DOI 10.1158/1535-7163.MCT-06-0113
    • Kamath K., Okouneva T., Larson G., Panda D., Wilson L., Jordan M.A. 2-methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Mol. Cancer Ther., 6: 2225-2233, 2006. (Pubitemid 44530459)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.9 , pp. 2225-2233
    • Kamath, K.1    Okouneva, T.2    Larson, G.3    Panda, D.4    Wilson, L.5    Jordan, M.A.6
  • 17
    • 0036645421 scopus 로고    scopus 로고
    • 2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of oestrogen receptors alpha and beta
    • LaVallee T.M., Zhan X.H., Herbstritt C.J., Kough E.C., Green S.J., Pribluda V.S. 2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of oestrogen receptors alpha and beta. Cancer Res., 62: 3691-3697, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 3691-3697
    • Lavallee, T.M.1    Zhan, X.H.2    Herbstritt, C.J.3    Kough, E.C.4    Green, S.J.5    Pribluda, V.S.6
  • 19
    • 4344659253 scopus 로고    scopus 로고
    • 2-Methoxyestradiol inhibits proliferation of normal and neoplastic glial cells, and induces cell death, in vitro
    • DOI 10.1016/j.canlet.2004.04.021, PII S0304383504003702
    • Lis A., Ciesielski M.J., Barone T.A., Scott B.E., Fenstermaker R.A., Plunkett R.J. 2-Methoxyestradiol inhibits proliferation of normal and neoplastic glial cells, and induces cell death, in vitro. Cancer Lett., 213: 57-65, 2004. (Pubitemid 39118534)
    • (2004) Cancer Letters , vol.213 , Issue.1 , pp. 57-65
    • Lis, A.1    Ciesielski, M.J.2    Barone, T.A.3    Scott, B.E.4    Fenstermaker, R.A.5    Plunkett, R.J.6
  • 21
    • 0031039519 scopus 로고    scopus 로고
    • Tubulin post-translational modifications: Enzymes and their mechanisms of action
    • MacRae T.H. Tubulin post-translational modifications: enzymes and their mechanisms of action. Eur. J. Biochem., 244: 265-278, 1997.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 265-278
    • MacRae, T.H.1
  • 22
    • 0018574156 scopus 로고
    • Impact of continuously administered catechol estrogens on uterine growth and luteinizing hormone secretion
    • Martucci C.P. and Fishman J. Impact of continuously administered catechol estrogens on uterine growth and luteinizing hormone secretion. Endocrinology, 105: 1288-1292, 1979. (Pubitemid 10164801)
    • (1979) Endocrinology , vol.105 , Issue.6 , pp. 1288-1292
    • Martucci, C.P.1    Fishman, J.2
  • 23
    • 0024580181 scopus 로고
    • Characteristics of microtubules at the different stages of neuronal differentiation and maturation
    • Meninger V. and Binet S. Characteristics of micro- tubules at the different stages of neuronal differentiation and maturation. Int. Rev. Cyt., 64: 21-79, 1989. (Pubitemid 19124968)
    • (1989) International Review of Cytology , vol.114 , pp. 21-79
    • Meininger, V.1    Binet, S.2
  • 24
    • 0021092708 scopus 로고
    • Microheterogeneity of tubulin proteins in neuronal and glial cells from the mouse brain in culture
    • Moura Neto V., Mallat M., Jeantet C., Prochiantzl A. Microheterogeneity of tubulin proteins in neuronal and glial cells from the mouse brain in culture. EMBO J., 8: 1243-1248, 1983.
    • (1983) EMBO J. , vol.8 , pp. 1243-1248
    • Moura Neto, V.1    Mallat, M.2    Jeantet, C.3    Prochiantzl, A.4
  • 25
    • 0029880479 scopus 로고    scopus 로고
    • The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro
    • DOI 10.1016/0024-3205(96)00116-6
    • Nakagawa-Yagi Y., Ogane N., Inoki Y., Kitoh N. The endogenous estrogen metabolite 2-methoxyestra-diol induces apoptotic neuronal cell death in vitro. Life Sci., 17: 1461-1467, 1996. (Pubitemid 26124374)
    • (1996) Life Sciences , vol.58 , Issue.17 , pp. 1461-1467
    • Nakagawa-Yagi, Y.1    Ogane, N.2    Inoki, Y.3    Kitoh, N.4
  • 26
    • 0141884323 scopus 로고    scopus 로고
    • Neuroprotective and neurotoxic effects of estrogens
    • DOI 10.1016/S0006-8993(03)03380-8
    • Picazo O., Azcoitia I., Garcia-Segura M. Neuroprotective and neurotoxic effects of estrogens. Brain Res., 990: 20-27, 2003. (Pubitemid 37244057)
    • (2003) Brain Research , vol.990 , Issue.1-2 , pp. 20-27
    • Picazo, O.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 27
    • 0023293040 scopus 로고
    • Microtubules containing acetylated α-tubulin in mammalian cells in culture
    • Piperno G., LeDizet M., Chang XJ. Microtubules containing acetylated α-tubulin in mammalian cells in culture. J. Cell Biol., 104: 289-302, 1987.
    • (1987) J. Cell Biol. , vol.104 , pp. 289-302
    • Piperno, G.1    Ledizet, M.2    Chang, X.J.3
  • 29
    • 0029990387 scopus 로고    scopus 로고
    • Microtubule stability decreases axon elongation but no axoplasm production
    • Rochlin M.W., Wickline K.M., Bridgman P.C. Microtubule stability decreases axon elongation but no axoplasm production. J. Neurosci., 16: 3236-3246, 1996.
    • (1996) J. Neurosci. , vol.16 , pp. 3236-3246
    • Rochlin, M.W.1    Wickline, K.M.2    Bridgman, P.C.3
  • 30
    • 0038011249 scopus 로고    scopus 로고
    • 2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis
    • Shimada K., Nakamura M., Ishida E., Kishi M., Konishi N. Roles of p38 and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestra-diol-induced p53 induction and apoptosis. Carcinogenesis, 24: 1067-1075, 2003. (Pubitemid 36827258)
    • (2003) Carcinogenesis , vol.24 , Issue.6 , pp. 1067-1075
    • Shimada, K.1    Nakamura, M.2    Ishida, E.3    Kishi, M.4    Konishi, N.5
  • 31
    • 0024373582 scopus 로고
    • The cytotoxic effects of estradiol-17beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and HeLa cells
    • DOI 10.1016/0022-4731(89)90455-X
    • Seegers J.C., Aveling M.L., Van Aswegen C.H., Cross M., Koch F., Joubert W.S. The cytotoxic effects of estradiol-17 beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and HeLa cells. J. Steroid Biochem., 6: 797-809, 1989. (Pubitemid 19192324)
    • (1989) Journal of Steroid Biochemistry , vol.32 , Issue.6 , pp. 797-809
    • Seegers, J.C.1    Aveling, M.-L.2    Van Aswegen, C.H.3    Cross, M.4    Koch, F.5    Joubert, W.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.