Estrogen-induced relaxation of the rat tail artery is attenuated in rats with pulmonary hypertension

Pharmacological Reports

Volumn 62, Issue 1, 2010, Pages 95-99

  Kocić, Ivan ^a   Szczepańska, Renata ^a   Wapniarska, Iga ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Endothelium; Estrogen; Nitric oxide; Pulmonary arterial hypertension; Rat; Tail artery; 1 receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ESTRADIOL; ESTROGEN; MONOCROTALINE; NITRIC OXIDE; PHENYLEPHRINE; PROSTANOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SENSITIVITY; MALE; MOLECULAR MECHANICS; NONHUMAN; PULMONARY HYPERTENSION; RAT; TAIL ARTERY; VASODILATATION;

EID: 77950842878     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(10)70246-2     Document Type: Article

References (19)

1. Araki H, Nishi K, Jougasaki M: Effects of thrombosis on vascular tone in rat mesenteric arteries with endothelium in vivo. Circ Res, 1990, 67, 312-318.
2. Bauersachs J, Widder JD: Endothelial disfunction in heart failure. Pharmacol Rep, 2008, 60, 119-126.
3. Chan HY, Yao X, Tsang SY, Chan FL, Lau CW, Huang Y. Different role of endothelium/nitric oxide in 17 estradiol-and progesterone-induced relaxation in rat arteries. Life Sci, 2001, 69, 1609-1617.
4. Chan HY, Yao X, Tsang SY, Bourreau JP, Chan FL, Hunag Y: Isoproterenol amplifies 17β-estradiol-mediated vasorelaxation: role of endothelium/nitric oxide and cyclic AMP. Cardiovasc Res, 2002, 53, 627-633.
5. Chataigneau T, Schini-Kerth VB: Vascular effects of ovariectomy and chronic oestrogen treatment in rats: controversy or experimental protocol diversity? Br J Pharmacol, 2005, 144, 161-163.
6. Duckles SP, Krause DN: Cerebrovascular effects of oestrogen: multiplicity of action. Clin Exp Pharmacol Physiol, 2007, 801-808.
7. Feletou M, Vanhoutte PM: EDHF: new therapeutic target. Pharm Res, 2004, 49, 565-580.
8. Garcia-Villalon AL, Buchholz JN, Krause DN, Duckles SP: Sex differences in the effects of 17β-estradiol on vascular adrenergic responses. Eur J Pharmacol, 1996, 314,339-345.
9. Gonzales RJ, Kanagy NL: Endothelium-independent relaxation of vascular smooth muscle by 17beta-estradiol. J Cardiovasc Pharmacol Ther, 1999, 4, 227-234.
10. Han G, Yu X, Lu L, Li S, Ma H, Zhu S, Cui X, White RE: Estrogen receptor mediates acute potassium channel stimulation in human coronary artery smooth muscle cells. J Pharmacol Exp Ther, 2006, 316, 1025-1030.
11. Kocić I, Gruchała-Niedoszytko M: Pinacidil relaxing effect on phenylephrine-precontracted guinea pig aorta was abolished by pretreatment with 17β-estradiol. Int J Cardiol, 2009, 133, 116-118.
12. Lahm T, Crisostomo PR, Markel TA, Wang M, Wang Y, Tan J, Meldrum DR: Selective estrogen receptor-α and estrogen receptor-β agonists rapidly decrease pulmonary artery vasoconstriction by a nitric oxide-dependent mechanism. Am J Physiol Regular Integr Comp Physiol, 2008,295, R1486-R1493.
13. Ma L, Robinson CP, Thadani U, Patterson E: Effect of 17β-estradiol in the rabbit: endothelium-dependent and independent mechanisms of vascular relaxation. J Cardiovasc Pharmacol, 1997, 30, 130-135.
14. Naeije R, Dewachter L: Animal models of pulmonary arterial hypertension. Rev Mal Respir, 2007, 24, 481-496.
15. Nicholas TE: A perfused rat tail artery preparation from the rat. J Pharm Pharmacol, 1969, 21, 826-832.
16. Shan J, Resnick M, Liu QY, Wu XC, Barbagallo M, Pang PK: Vascular effects of 17β-estradiol in male Sprague-Dawley rats. Circ Res, 1994, 266, 967-973.
17. Villar IC, Francis S, Webb A, Hobbs AJ, Ahluwalia A: Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int, 2006, 70, 840-853.
18. Ca channels through a cGMP-dependent mechanism. Circ Res, 1995, 77, 936-942.
19. + channels in human coronary artery smooth muscle cells. Cardiovasc Res, 2002, 53, 650-661.