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Volumn 31, Issue 2, 2010, Pages 112-119

Comprehensive review of olopatadine: The molecule and its clinical entities

Author keywords

Allergic conjunctivitis; Allergic rhinitis; Antihistamine; Mast cell stabilizer; Nasal allergy; Nasal antihistamine; Ocular allergy; Olopatadine

Indexed keywords

ANTIHISTAMINIC AGENT; ANTIINFLAMMATORY AGENT; AZELASTINE; EPINASTINE; LORATADINE; MOMETASONE FUROATE; OLOPATADINE; PATADAY; PATANASE; PLACEBO; STEROID; UNCLASSIFIED DRUG;

EID: 77950841759     PISSN: 10885412     EISSN: 15396304     Source Type: Journal    
DOI: 10.2500/aap.2010.31.3317     Document Type: Review
Times cited : (37)

References (47)
  • 4
    • 0009005916 scopus 로고
    • Effect of KW-4679, a novel antiallergic agent, on histamine H1 receptor
    • Abs O-83
    • Nonaka H, Ishii A, and Kase H. Effect of KW-4679, a novel antiallergic agent, on histamine H1 receptor. Jpn J Pharmacol 61(suppl 1):87, 1993 (Abs O-83).
    • (1993) Jpn J Pharmacol , vol.61 , Issue.SUPPL. 1 , pp. 87
    • Nonaka, H.1    Ishii, A.2    Kase, H.3
  • 5
    • 0029853560 scopus 로고    scopus 로고
    • Olopatadine (AL-4943A): Ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis
    • Sharif NA, Xu SX, and Yanni JM. Olopatadine (AL-4943A): Ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis. J Ocul Pharmacol 12:401-407, 1996.
    • (1996) J Ocul Pharmacol , vol.12 , pp. 401-407
    • Sharif, N.A.1    Xu, S.X.2    Yanni, J.M.3
  • 6
    • 0030218814 scopus 로고    scopus 로고
    • Histamine enhanced the TNF-α-induced expression of E-selectin and ICAM-1 on vascular endothelial cells
    • DOI 10.1006/cimm.1996.0205
    • Miki I, Kusano A, Ohta S, et al. Histamine enhanced the TNF- α-induced expression of E-selectin and ICAM-1 on vascular endothelial cells. Cell Immunol 171:285-288, 1996. (Pubitemid 26268486)
    • (1996) Cellular Immunology , vol.171 , Issue.2 , pp. 285-288
    • Miki, I.1    Kusano, A.2    Ohta, S.3    Hanai, N.4    Otoshi, M.5    Masaki, S.6    Sato, S.7    Ohmori, K.8
  • 7
    • 0032942496 scopus 로고    scopus 로고
    • Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs
    • Yanni JM, Weimer LK, Sharif NA, et al. Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs. Arch Opthalmol 117:643-647, 1999.
    • (1999) Arch Opthalmol , vol.117 , pp. 643-647
    • Yanni, J.M.1    Weimer, L.K.2    Sharif, N.A.3
  • 9
    • 0031449146 scopus 로고    scopus 로고
    • Comparative effects of topical ocular anti-allergy drugs on human conjunctival mast cells
    • Yanni JM, Miller ST, Gamache DA, et al. Comparative effects of topical ocular anti-allergy drugs on human conjunctival mast cells. Ann Allergy Asthma Immunol 79:541-545, 1997.
    • (1997) Ann Allergy Asthma Immunol , vol.79 , pp. 541-545
    • Yanni, J.M.1    Miller, S.T.2    Gamache, D.A.3
  • 10
    • 0000567036 scopus 로고
    • Effect of KW-4679, an novel antiallergic drug on histamine and leukotriene release from rat peritoneal exudates cells
    • Sasaki Y, Ikeda Y, Ikemura T, et al. Effect of KW-4679, an novel antiallergic drug on histamine and leukotriene release from rat peritoneal exudates cells. Clin Pharmacol Ther 5:1837-1849, 1995.
    • (1995) Clin Pharmacol Ther , vol.5 , pp. 1837-1849
    • Sasaki, Y.1    Ikeda, Y.2    Ikemura, T.3
  • 12
    • 0346880172 scopus 로고    scopus 로고
    • Interactions of olopatadine and selected antihistamines with model and natural membranes
    • Brockman HL, Mornsen MM, Knudtson JR, et al. Interactions of olopatadine and selected antihistamines with model and natural membranes. Ocul Immunol Inflamm 11:247-268, 2003.
    • (2003) Ocul Immunol Inflamm , vol.11 , pp. 247-268
    • Brockman, H.L.1    Mornsen, M.M.2    Knudtson, J.R.3
  • 14
    • 0035170468 scopus 로고    scopus 로고
    • Olopatadine inhibits anti-immunolglobulin E-stimulated conjunctival mast cell upregulation of ICAM-1 expression on conjunctival epithelial cells
    • Cook EB, Stahl JL, Barney NP, and Graziano FM. Olopatadine inhibits anti-immunolglobulin E-stimulated conjunctival mast cell upregulation of ICAM-1 expression on conjunctival epithelial cells. Ann Allergy Asthma Immunol 87:424-429, 2000.
    • (2000) Ann Allergy Asthma Immunol , vol.87 , pp. 424-429
    • Cook, E.B.1    Stahl, J.L.2    Barney, N.P.3    Graziano, F.M.4
  • 16
    • 35848937145 scopus 로고    scopus 로고
    • Duration of action of topical antiallergy drugs in a guinea pig model of histamine-induced conjunctival vascular permeability
    • DOI 10.1089/jop.2006.0138
    • Beauregard C, Stephens D, Leighann R, et al. Duration of action of topical antiallergy drugs in a guinea pig model of histamine-induced conjunctival vascular permeability. J Ocul Pharmacol Ther 23:315-320, 2007. (Pubitemid 350195055)
    • (2007) Journal of Ocular Pharmacology and Therapeutics , vol.23 , Issue.4 , pp. 315-320
    • Beauregard, C.1    Stephens, D.2    Roberts, L.3    Gamache, D.4    Yanni, J.5
  • 17
    • 1642336338 scopus 로고    scopus 로고
    • Ocular tissue distribution of olopatadine following a single topical ocular dose of a 0.2% olopatadine ophthalmic solution to male New Zealand white rabbits
    • Roy AK. Ocular tissue distribution of olopatadine following a single topical ocular dose of a 0.2% olopatadine ophthalmic solution to male New Zealand white rabbits. Alcon Internal Report 023:33:0502, 2002.
    • (2002) Alcon Internal Report 023:33:0502
    • Roy, A.K.1
  • 20
    • 0031661326 scopus 로고    scopus 로고
    • Evaluation of olopatadine, a new ophthalmic antiallergic agnet with dual activity, using conjunctival allergen challence
    • Abelson MB. Evaluation of olopatadine, a new ophthalmic antiallergic agnet with dual activity, using conjunctival allergen challence. Ann Allergy Asthma Immunol 81:211-218, 1998.
    • (1998) Ann Allergy Asthma Immunol , vol.81 , pp. 211-218
    • Abelson, M.B.1
  • 21
    • 0037361910 scopus 로고    scopus 로고
    • A randomized, double-blind, parallel-group comparison of olopatadine 0.1% Ophthalmic solution versus placebo for controlling the signs and symptoms of seasonal allergic conjunctivitis and rhinoconjunctivitis
    • DOI 10.1016/S0149-2918(03)80115-7
    • Abelson MB, and Turner D. A randomized, double-blind, parallel- group comparison of olopatadine 0.1% ophthalmic solution versus placebo for controlling the signs and symptoms of seasonal allergic conjunctivitis and rhinoconjunctivitis. Clin Ther 25:931-947, 2003. (Pubitemid 36459699)
    • (2003) Clinical Therapeutics , vol.25 , Issue.3 , pp. 931-947
    • Abelson, M.B.1    Turner, D.2
  • 22
    • 0032586308 scopus 로고    scopus 로고
    • Comparative evaluation of olopatadine ophthalmic solution (0.1%) versus ketorolac ophthalmic solution (0.5%) using the provocative antigen challenge model
    • Deschenes J, Discepola M, and Abelson M. Comparative evaluation of olopatadine ophthalmic solution (0.1%) versus ketorolac ophthalmic solution (0.5%) using the provocative antigen challenge model. Acta Ophthalmol Scand 77:47-52, 1999.
    • (1999) Acta Ophthalmol Scand , vol.77 , pp. 47-52
    • Deschenes, J.1    Discepola, M.2    Abelson, M.3
  • 24
    • 33845203842 scopus 로고    scopus 로고
    • Efficacy and response with olopatadine versus epinastine in ocular allergic symptoms: A post hoc analysis of data from a conjunctival allergen challenge study
    • DOI 10.1016/j.clinthera.2006.10.003, PII S0149291806002438
    • Finegold I, Granet DB, D'Arienzo PA, and Epstein AB. Efficacy and response with olopatadine versus epinastine in ocular allergic symptoms: A post hoc analysis of data from a conjunctival allergen challenge study. Clin Ther 28:1630-1680, 2006. (Pubitemid 44848366)
    • (2006) Clinical Therapeutics , vol.28 , Issue.10 , pp. 1630-1638
    • Finegold, I.1    Granet, D.B.2    D'Arienzo, P.A.3    Epstein, A.B.4
  • 25
    • 0032586307 scopus 로고    scopus 로고
    • The added benefit of local patanol therapy when combined with systemic Claritin for the inhibition of ocular itching in the conjunctival antigen challenge model
    • Abelson MB, and Lanier RQ. The added benefit of local patanol therapy when combined with systemic Claritin for the inhibition of ocular itching in the conjunctival antigen challenge model. Acta Ophthalmol Scand 77:53-56, 1999.
    • (1999) Acta Ophthalmol Scand , vol.77 , pp. 53-56
    • Abelson, M.B.1    Lanier, R.Q.2
  • 26
    • 0034978607 scopus 로고    scopus 로고
    • Olopatadine ophthalmic solution adjunctive to loratadine compared with loratadine alone in patients with active seasonal allergic conjunctivitis symptoms
    • Lanier BQ, Gross RD, Marks BB, et al. Olopatadine ophthalmic solution adjunctive to loratadine compared with loratadine alone in patients with active seasonal allergic conjunctivitis symptoms. Ann Allergy Asthma Immun 86:641-648, 2001.
    • (2001) Ann Allergy Asthma Immun , vol.86 , pp. 641-648
    • Lanier, B.Q.1    Gross, R.D.2    Marks, B.B.3
  • 27
    • 6344248682 scopus 로고    scopus 로고
    • Clinical efficacy of olopatadine hydrochloride ophthalmic solution 0.2% compared with placebo in patients with allergic conjunctivitis or rhino-conjunctivitis: A randomized, double-masked environmental study
    • Abelson MB, Gomes PJ, Vogelson CT, et al. Clinical efficacy of olopatadine hydrochloride ophthalmic solution 0.2% compared with placebo in patients with allergic conjunctivitis or rhino-conjunctivitis: A randomized, double-masked environmental study. Clin Ther 26:1237-1248, 2004.
    • (2004) Clin Ther , vol.26 , pp. 1237-1248
    • Abelson, M.B.1    Gomes, P.J.2    Vogelson, C.T.3
  • 28
    • 34548641129 scopus 로고    scopus 로고
    • Efficacy of olopatadine ophthalmic solution 0.2% in reducing signs and symptoms of allergic conjunctivitis
    • Abelson MB, Gomes PJ, Pasquine T, et al. Efficacy of olopatadine ophthalmic solution 0.2% in reducing signs and symptoms of allergic conjunctivitis. Allergy Asthma Proc 28:427-433, 2007.
    • (2007) Allergy Asthma Proc , vol.28 , pp. 427-433
    • Abelson, M.B.1    Gomes, P.J.2    Pasquine, T.3
  • 29
    • 18844393097 scopus 로고    scopus 로고
    • Effects of a new formulation of olopatadine ophthalmic solution on nasal symptoms relative to placebo in two studies involving subjects with allergic conjunctivitis or rhinoconjunctivitis
    • Abelson MB, Gomes PJ, Vogelson CT, et al. Effects of a new formulation of olopatadine ophthalmic solution on nasal symptoms relative to placebo in two studies involving subjects with allergic conjunctivitis or rhinoconjunctivitis. Curr Med Res Opin 21:683-691, 2005.
    • (2005) Curr Med Res Opin , vol.21 , pp. 683-691
    • Abelson, M.B.1    Gomes, P.J.2    Vogelson, C.T.3
  • 30
    • 34347262074 scopus 로고    scopus 로고
    • Efficacy and comfort of olopatadine 0.2% versus epinastine 0.05% ophthalmic solution for treating itching and redness induced by conjunctival allergen challenge
    • DOI 10.1185/030079907X188206
    • Mah FS, Rosenwasser LJ, Townsend WD, et al. Efficacy and comfort of olopoatadine 0.2% versus epinastine 0.05% ophthalmic solution for treating itching and redness induced by conjunctival allergen challenge. Curr Med Res Opin 23:1445-1452, 2007. (Pubitemid 46998452)
    • (2007) Current Medical Research and Opinion , vol.23 , Issue.6 , pp. 1445-1452
    • Mah, F.S.1    Rosenwasser, L.J.2    Townsend, W.D.3    Greiner, J.V.4    Bensch, G.5
  • 31
    • 41749103627 scopus 로고    scopus 로고
    • Perception and quality of life associated with the use of olopatadine 0.2% (Pataday) in patients with active allergic conjunctivitis
    • Scoper SV, Berdy GJ, Lichtenstein SJ, et al. Perception and quality of life associated with the use of olopatadine 0.2% (Pataday) in patients with active allergic conjunctivitis. Adv Ther 24:1221-1232, 2007.
    • (2007) Adv Ther , vol.24 , pp. 1221-1232
    • Scoper, S.V.1    Berdy, G.J.2    Lichtenstein, S.J.3
  • 32
    • 77950837530 scopus 로고    scopus 로고
    • Low frequency of treatment-related ocular adverse events associated with olopatadine 0.2% (Pataday) in clinical trials
    • Edwards MR, Pasquine T, Gross RD, and Robertson SM. Low frequency of treatment-related ocular adverse events associated with olopatadine 0.2% (Pataday) in clinical trials. Allergy Asthma Proc 28:249, 2007.
    • (2007) Allergy Asthma Proc , vol.28 , pp. 249
    • Edwards, M.R.1    Pasquine, T.2    Gross, R.D.3    Robertson, S.M.4
  • 33
    • 39749169725 scopus 로고    scopus 로고
    • Evaluation of the effects of olopatadine ophthalmic solution, 0.2% on the ocular surface of patients with allergic conjunctivitis and dry eye
    • DOI 10.1185/030079908X261078
    • Mah FS, O'Brien T, Kim T, and Torkildsen G. Evaluation of the effects of olopatadine ophthalmic solution, 0.2% on the ocular surface of patients with allergic conjunctivitis and dry eye. Curr Med Res Opin 24:441-447, 2008. (Pubitemid 351294393)
    • (2008) Current Medical Research and Opinion , vol.24 , Issue.2 , pp. 441-447
    • Mah, F.S.1    O'Brien, T.2    Kim, T.3    Torkildsen, G.4
  • 35
    • 61749103050 scopus 로고    scopus 로고
    • Use of olopatadine ophthalmic solution and reactivity of histamine skin testing
    • Jones JD, Temino VM, Dworski R, et al. Use of olopatadine ophthalmic solution and reactivity of histamine skin testing. Allergy Asthma Proc 29:636-639, 2008.
    • (2008) Allergy Asthma Proc , vol.29 , pp. 636-639
    • Jones, J.D.1    Temino, V.M.2    Dworski, R.3
  • 38
    • 36649009739 scopus 로고    scopus 로고
    • Onset and duration of action of nasal sprays in seasonal allergic rhinitis patients: Olopatadine hydrochloride versus mometasone furoate monohydrate
    • Patel D, Garardi R, Brubaker M, et al. Onset and duration of action of nasal sprays in seasonal allergic rhinitis patients: Olopatadine hydrochloride versus mometasone furoate monohydrate. Allergy Asthma Proc 28:592-599, 2007.
    • (2007) Allergy Asthma Proc , vol.28 , pp. 592-599
    • Patel, D.1    Garardi, R.2    Brubaker, M.3
  • 41
    • 38349110611 scopus 로고    scopus 로고
    • Comprehensive report of the efficacy, safety, quality of life, and work impact of olopatadine 0.6% and olopatadine 0.4% treatment in patients with seasonal allergic rhinitis
    • Fairchild CJ, Meltzer EO, Roland PS, et al. Comprehensive report of the efficacy, safety, quality of life, and work impact of olopatadine 0.6% and olopatadine 0.4% treatment in patients with seasonal allergic rhinitis. Allergy Asthma Proc 28:716-723, 2007.
    • (2007) Allergy Asthma Proc , vol.28 , pp. 716-723
    • Fairchild, C.J.1    Meltzer, E.O.2    Roland, P.S.3
  • 42
    • 33746615667 scopus 로고    scopus 로고
    • Improved quality of life among seasonal allergic rhinitis patients treated with olopatadine HCl nasal spray 0.4% and olopatadine HCl nasal spray 0.6% compared with vehicle placebo
    • Hampel FC, Ratner PH, Amar NJ, et al. Improved quality of life among seasonal allergic rhinitis patients treated with olopatadine HCl nasal spray 0.4% and olopatadine HCl nasal spray 0.6% compared with vehicle placebo. Allergy Asthma Proc 27:202-207, 2006.
    • (2006) Allergy Asthma Proc , vol.27 , pp. 202-207
    • Hampel, F.C.1    Ratner, P.H.2    Amar, N.J.3
  • 43
    • 60649089429 scopus 로고    scopus 로고
    • Effects of olopatadine hydrochloride nasal spray 0.6% in the treatment of seasonal allergic rhinitis: A phase III, multicenter, randomized, double-blind, active- and placebo-controlled study in adolescents and adults
    • Shah SR, Nayak A, Ratner P, et al. Effects of olopatadine hydrochloride nasal spray 0.6% in the treatment of seasonal allergic rhinitis: A phase III, multicenter, randomized, double-blind, active- and placebo-controlled study in adolescents and adults. Clin Ther 31:99-107, 2009.
    • (2009) Clin Ther , vol.31 , pp. 99-107
    • Shah, S.R.1    Nayak, A.2    Ratner, P.3
  • 44
    • 61749104342 scopus 로고    scopus 로고
    • Comparative study of sensory attributes of two antihistamine nasal sprays: Olopatadine 0.6% and azelastine 0.1%
    • Meltzer EO, Garadi R, Laforce C, et al. Comparative study of sensory attributes of two antihistamine nasal sprays: Olopatadine 0.6% and azelastine 0.1%. Allergy Asthma Proc 29:659-668, 2008.
    • (2008) Allergy Asthma Proc , vol.29 , pp. 659-668
    • Meltzer, E.O.1    Garadi, R.2    Laforce, C.3
  • 45
    • 66449123627 scopus 로고    scopus 로고
    • Pharmacokinetic characteristics and safety and tolerability of a reformulated azelastine hydrochloride nasal spray in patients with chronic rhinitis
    • Berger WE. Pharmacokinetic characteristics and safety and tolerability of a reformulated azelastine hydrochloride nasal spray in patients with chronic rhinitis. Expert Opin Drug Metab Toxicol 5:91-102, 2009.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 91-102
    • Berger, W.E.1
  • 46
    • 68249157077 scopus 로고    scopus 로고
    • Comparison of olopatadine 0.6% nasal spray versus fluticasone propionate 50 mcg in the treatment of seasonal allergic rhinitis
    • Kaliner MA, Storms W, Tilles S, et al. Comparison of olopatadine 0.6% nasal spray versus fluticasone propionate 50 mcg in the treatment of seasonal allergic rhinitis. Allergy Asthma Proc 30:259-262, 2009.
    • (2009) Allergy Asthma Proc , vol.30 , pp. 259-262
    • Kaliner, M.A.1    Storms, W.2    Tilles, S.3


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