Imperfect oligodendrocytic and neuronal differentiation of glioblastoma cells

Folia Neuropathologica

Volumn 48, Issue 1, 2010, Pages 27-34

  Wolańczyk, Magdalena ^a   Hułas Bigoszewska, Krystyna ^a   Witusik Perkowska, Monika ^a   Papierz, Wielisław ^a   Jaskólski, Dariusz ^a   Liberski, Paweł P ^a   Rieske, Piotr ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Differentiation arrest; EGFR; GBM; Neural differentiation; Oligodendrocytic differentiation

Indexed keywords

4 AMINOBUTYRIC ACID CARRIER; BASIC FIBROBLAST GROWTH FACTOR; BIOLOGICAL MARKER; CATECHOLAMINE TRANSPORTER; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; THYROID HORMONE; TYROSINE 3 MONOOXYGENASE;

ARTICLE; CELL CYCLE ARREST; CELL LINEAGE; CULTURE MEDIUM; GENE AMPLIFICATION; GENE EXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NERVE CELL DIFFERENTIATION; NUCLEOTIDE SEQUENCE; OLIGODENDROGLIA; PHENOTYPE; SEQUENCE ANALYSIS;

EID: 77950839521     PISSN: 16414640     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Biernat W, Tohma Y, Yonekawa Y, Kleihues P, Ohgaki H. Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas. Acta Neuropathol 1997; 94: 303-309. (Pubitemid 27450108)
2. Bögler O, Wren D, Barnett SC, Land H, Noble M. Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells. Proc Natl Acad Sci U S A 1990; 87: 6368- 6372. (Pubitemid 120030303)
3. von Deimling A, von Ammon K, Schoenfeld D, Wiestler OD, Seizinger BR, Louis DN. Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol 1993; 3: 19-26. (Pubitemid 23046372)
4. Günther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria. Oncogene 2008; 27: 2897-2909. (Pubitemid 351620450)
5. Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, Steindler DA. Human cortical glial tumors contain neural stemlike cells expressing astroglial and neuronal markers in vitro. Glia 2002; 39: 193-206.
6. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007; 2: 97-109. (Pubitemid 47103521)
7. Ohgaki H, Eibl RH, Schwab M, Reichel MB, Mariani L, Gehring M, Petersen I, Höll T, Wiestler OD, Kleihues P. Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system. Mol Carcinog 1993; 8: 74-80. (Pubitemid 23296312)
8. Ricci-Vitiani L, Pallini R, Larocca LM, Lombardi DG, Signore M, Pierconti F, Petrucci G, Montano N, Maira G, De Maria R. Me senchymal differentiation of glioblastoma stem cells. Cell Death Differ 2008; 15: 1491-1498.
9. Rieske P, Azizi SA, Augelli B, Gaughan J, Krynska B. A population of human brain parenchymal cells express markers of glial, neuronal and early neural cells and differentiate into cells of neuronal and glial lineages. Eur J Neurosci 2007; 25: 31-37. (Pubitemid 46096220)
10. Rieske P, Golanska E, Zakrzewska M, Piastowski S, Hulas-Bigoszewska K, Wolańczyk M, Szybka M, Witusik-Perkowska M, Jaskolski D, Zakrzewski K, Biernat W, Krymska B, Liberski PP. Arrested neural and advanced mesenchymal differentiation of glioblastoma cells - comparative study with neural progenitors. BMC Cancer 2009; 9: 54.
11. Szybka M, Bartkowiak J, Zakrzewski K, Polis L, Liberski P, Kordek R. Microsatellite instability and expression of DNA mismatch repair genes in malignant astrocytic tumors from adult and pediatric patients. Clin Neuropathol 2003; 22: 180-186. (Pubitemid 36869992)
12. Witusik M, Gresner SM, Hulas-Bigoszewska K, Krynska B, Azizi SA, Liberski PP, Brown P, Rieske P. Neuronal and astrocytic cells, obtained after differentiation of human neural GFAP-positive progenitors, present heterogeneous expression of PrPc. Brain Res 2007; 1186: 65-73.